hyperoside

quercetin 3-O-b-D-galactopyranoside

CAS: 482-36-0 C21 H20 O12 MW: 464.38080000

Identification

Namehyperoside
CAS Number482-36-0
EINECS207-580-6
FDA UNII8O1CR18L82
Molecular FormulaC21 H20 O12
Molecular Weight464.38080000
MDL NumberMFCD00016933
Nikkaji NumberJ12.400A
Beilstein5784795

Regulatory

FDA/DG SANTE Petitions, Reviews, NoticesGRN 530

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 872.63 °C. @ 760.00 mm Hg (est)
Flash Point 585.00 °F. TCC ( 307.50 °C. ) (est)
logP (o/w) -0.111 (est)
Soluble in water, 2.782e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfood additive
Recommendation for hyperoside usage levels up tonot for fragrance use.
Recommendation for hyperoside flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

allspice anise star anise plant apple fruit juice apple heart wood apple peel PMC apple pericarp apple plant apricot fruit bilberry fruit bilberry fruit juice bilberry leaf blueberry plant buckwheat seed buckwheat testa cacao plant caraway seed celery plant chamomile sweet false chamomile plant cherry sour cherry plant chicory leaf chicory plant chicory shoot clove fruit cranberry fruit dill leaf elder black elder plant grape leaf guava leaf horseradish leaf loquat shoot lotus indian lotus flower pepper black pepper fruit sorrel garden sorrel leaf spinach shoot st. john's wort tarragon shoot tea leaf walnut english walnut leaf

Synonyms

4H-1- benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(b-D-galactopyranosyloxy)-5,7-dihydroxy- 2-(3,4- dihydroxyphenyl)-3-(beta-dextro-galactopyranosyl oxy)-5,7-dihydroxy-4H-1-benzopyran-4-one 2-(3,4- dihydroxyphenyl)-3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one 2-(3,4- dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 2-(3,4- dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl b-D-galactopyranoside hydroside hyperasid hyperin hyperosid hyperozide quercetin 3-b-D-galactopyranoside quercetin 3-D-galactoside quercetin 3-O-b-D-galactopyranoside quercetin-3-D-galactoside PubMed: Modeling of the total antioxidant capacity of rooibos (Aspalathus linearis) tea infusions from chromatographic fingerprints and identification of potential antioxidant markers. PubMed: Purification and characterization of flavonoids from the leaves of Zanthoxylum bungeanum and correlation between their structure and antioxidant activity. PubMed: Phytochemical profiles and antioxidant and antimicrobial activities of the leaves of Zanthoxylum bungeanum. PubMed: Ionic liquid-based one-step micellar extraction of multiclass polar compounds from hawthorn fruits by ultrahigh-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry. PubMed: Flavonol glycosides and other phenolic compounds in buds and leaves of different varieties of black currant (Ribes nigrum L.) and changes during growing season. PubMed: Hyperoside and anthocyanin content of ten different pomegranate cultivars. PubMed: Quantification of individual phenolic compounds' contribution to antioxidant capacity in apple: a novel analytical tool based on liquid chromatography with diode array, electrochemical, and charged aerosol detection. PubMed: Hyperoside downregulates the receptor for advanced glycation end products (RAGE) and promotes proliferation in ECV304 cells via the c-Jun N-terminal kinases (JNK) pathway following stimulation by advanced glycation end-products in vitro. PubMed: Comparative analysis of Tunisian wild Crataegus azarolus (yellow azarole) and Crataegus monogyna (red azarole) leaf, fruit, and traditionally derived syrup: phenolic profiles and antioxidant and antimicrobial activities of the aqueous-acetone extracts. PubMed: Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6. PubMed: Determination of hyperin in seed of Cuscuta chinensis Lam. by enhanced chemiluminescence of CdTe quantum dots on calcein/K3Fe(CN)6 system. PubMed: Potent α-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris. PubMed: Polyphenolics composition of the leaves of Zanthoxylum bungeanum Maxim. grown in Hebei, China, and their radical scavenging activities. PubMed: Development of a validated HPLC method for the simultaneous determination of flavonoids in Cuscuta chinensis Lam. by ultra-violet detection. PubMed: Quantitative and Chemical Fingerprint Analysis for the Quality Evaluation of Receptaculum Nelumbinis by RP-HPLC Coupled with Hierarchical Clustering Analysis. PubMed: Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside. PubMed: Variation in phenolic content and antioxidant activity of fermented rooibos herbal tea infusions: role of production season and quality grade. PubMed: Inhibitory activity of coumarins from Artemisia capillaris against advanced glycation endproduct formation. PubMed: Hepatoprotection with a chloroform extract of Launaea procumbens against CCl4-induced injuries in rats. PubMed: Assessment of flavonoids contents and in vitro antioxidant activity of Launaea procumbens. PubMed: A review of the chemistry of the genus Crataegus. PubMed: Chemical composition and hepatoprotective effects of polyphenol-rich extract from Houttuynia cordata tea. PubMed: Between species diversity of Hypericum perforatum and H. maculatum by the content of bioactive compounds. PubMed: Pretreatment with the total flavone glycosides of Flos Abelmoschus manihot and hyperoside prevents glomerular podocyte apoptosis in streptozotocin-induced diabetic nephropathy. PubMed: Phenolic composition in different genotypes of Guabiju fruits (Myrcianthes pungens) and their potential as antioxidant and antichemotactic agents. PubMed: Comparative analysis of the chemical composition and antioxidant activity of red (Psidium cattleianum) and yellow (Psidium cattleianum var. lucidum) strawberry guava fruit. PubMed: Phenolic compounds in hawthorn (Crataegus grayana) fruits and leaves and changes during fruit ripening. PubMed: Quantitative analysis of phenolic compounds in Chinese hawthorn (Crataegus spp.) fruits by high performance liquid chromatography-electrospray ionisation mass spectrometry. PubMed: Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat. PubMed: Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki. PubMed: Edible neotropical blueberries: antioxidant and compositional fingerprint analysis. PubMed: Extraction and identification of three major aldose reductase inhibitors from Artemisia montana. PubMed: Consumption of polyphenol concentrate with dietary fructo-oligosaccharides enhances cecal metabolism of quercetin glycosides in rats. PubMed: Highly variable contents of phenolics in St. John's Wort products affect their transport in the human intestinal Caco-2 cell model: pharmaceutical and biopharmaceutical rationale for product standardization. PubMed: Synergetic effect and structure-activity relationship of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors from Crataegus pinnatifida Bge. PubMed: Isolation and purification of three flavonoid glycosides from the leaves of Nelumbo nucifera (Lotus) by high-speed counter-current chromatography. PubMed: Protective effects of leaf extract of Zanthoxylum ailanthoides on oxidation of low-density lipoprotein and accumulation of lipid in differentiated THP-1 cells. PubMed: Anti-inflammatory, gastroprotective, free-radical-scavenging, and antimicrobial activities of hawthorn berries ethanol extract. PubMed: Bioactive constituent production in St. John's Wort in vitro hairy roots. Regenerated plant lines. PubMed: Effect of Albizia julibrissin water extracts on low-density lipoprotein oxidization. PubMed: Phenolic compounds, organic acids profiles and antioxidative properties of beefsteak fungus (Fistulina hepatica). PubMed: Quantification of the polyphenols and triterpene acids in chinese hawthorn fruit by high-performance liquid chromatography. PubMed: Comparison of methods for the exhaustive extraction of hypericins, flavonoids, and hyperforin from Hypericum perforatum L. PubMed: Approach to novel functional foods for stress control 5. Antioxidant activity profiles of antidepressant herbs and their active components. PubMed: An improved method for the quantitation of flavonoids in Herba Leonuri by capillary electrophoresis. PubMed: Inhibitors of the epidermal growth factor receptor in apple juice extract. PubMed: Herbal drug quality and phytochemical composition of Hypericum perforatum L. affected by ash yellows phytoplasma infection. PubMed: Antifungal activity of camptothecin, trifolin, and hyperoside isolated from Camptotheca acuminata. PubMed: Antioxidant activity of a flavonoid-rich extract of Hypericum perforatum L. in vitro. PubMed: The type of sugar moiety is a major determinant of the small intestinal uptake and subsequent biliary excretion of dietary quercetin glycosides. PubMed: Unfermented rooibos tea: quantitative characterization of flavonoids by HPLC-UV and determination of the total antioxidant activity. PubMed: Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (Hawthorn) subjected to drought and cold stress.