ternatin
4H-1-benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7,8-trimethoxy-
Identification
| Name | ternatin |
| IUPAC | 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7,8-trimethoxychromen-4-one |
| CAS Number | 571-71-1 |
| FDA UNII | G60G0VQS3I |
| Molecular Formula | C19 H18 O8 |
| Molecular Weight | 374.34606000 |
| Nikkaji Number | J94.561G |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 100.4 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ternatin usage levels up to | not for fragrance use. |
| Recommendation for ternatin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
4H-1-
benzopyran-4-one, 5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7,8-trimethoxy-
4',5-
dihydroxy-3,3',7,8-tetramethoxyflavone
5-
hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7,8-trimethoxychromen-4-one
ternatin (flavonoid)
PubMed:
Protective Role of Ternatin Anthocyanins and Quercetin Glycosides from Butterfly Pea (Clitoria ternatea Leguminosae) Blue Flower Petals against Lipopolysaccharide (LPS)-Induced Inflammation in Macrophage Cells.
PubMed:
Structural basis for acceptor-substrate recognition of UDP-glucose: anthocyanidin 3-O-glucosyltransferase from Clitoria ternatea.
PubMed:
Crystal structure of UDP-glucose:anthocyanidin 3-O-glucosyltransferase from Clitoria ternatea.
PubMed:
Effects of bioflavonoid ternatin on liver regeneration and oxidative stress in rats.
PubMed:
Ternatin, a cyclic peptide isolated from mushroom, and its derivative suppress hyperglycemia and hepatic fatty acid synthesis in spontaneously diabetic KK-A(y) mice.
PubMed:
Ternatin pretreatment attenuates testicular injury induced by torsion/detorsion in Wistar rats.
PubMed:
(-)-Ternatin inhibits adipogenesis and lipid metabolism in 3T3-L1 cells.
PubMed:
Importance of the backbone conformation of (-)-ternatin in its fat-accumulation inhibitory activity against 3T3-L1 adipocytes.
PubMed:
Structure-based hybridization of the bioactive natural products rhizonin A and ternatin leading to a selective fat-accumulation inhibitor against 3T3-L1 adipocytes.
PubMed:
Chemodiversity of exudate flavonoids in Cassinia and Ozothamnus (Asteraceae, Gnaphalieae).
PubMed:
Design, synthesis, and biological evaluation of biotin-labeled (-)-ternatin, a potent fat-accumulation inhibitor against 3T3-L1 adipocytes.
PubMed:
Whole structure-activity relationships of the fat-accumulation inhibitor (-)-ternatin: recognition of the importance of each amino acid residue.
PubMed:
Biological activity, structural features, and synthetic studies of (-)-ternatin, a potent fat-accumulation inhibitor of 3T3-L1 adipocytes.
PubMed:
Synthesis and inhibitory effect on fat accumulation of (-)-ternatin derivatives modified in the beta-OH-D-Leu(7) moiety.
PubMed:
Purification and characterization of UDP-glucose: anthocyanin 3',5'-O-glucosyltransferase from Clitoria ternatea.
PubMed:
Convergent synthesis and in vivo inhibitory effect on fat accumulation of (-)-ternatin, a highly N-methylated cyclic peptide.
PubMed:
Identification of diverse microbial metabolites as potent inhibitors of HIV-1 Tat transactivation.
PubMed:
Identification of delphinidin 3-O-(6''-O-malonyl)-beta-glucoside-3'-O-beta-glucoside, a postulated intermediate in the biosynthesis of ternatin C5 in the blue petals of Clitoria ternatea (butterfly pea).
PubMed:
Ternatin, a flavonoid, prevents cyclophosphamide and ifosfamide-induced hemorrhagic cystitis in rats.
PubMed:
Ternatin, an anti-inflammatory flavonoid, inhibits thioglycolate-elicited rat peritoneal neutrophil accumulation and LPS-activated nitric oxide production in murine macrophages.
PubMed:
New erythroxane-type diterpenoids from Fagonia boveana (Hadidi) Hadidi & Graf.
PubMed:
Antiproliferative effects of compounds derived from plants of Northeast Brazil.
PubMed:
Inhibition by the bioflavonoid ternatin of aflatoxin B1-induced lipid peroxidation in rat liver.
PubMed:
Investigations on the gastroprotective and antidiarrhoeal properties of ternatin, a tetramethoxyflavone from Egletes viscosa.
PubMed:
Inhibition of lipid peroxidation by ternatin, a tetramethoxyflavone from Egletes viscosa L.
PubMed:
Five new anthocyanins, ternatins A3, B4, B3, B2, and D2, from Clitoria ternatea flowers.
PubMed:
Biologically active flavonoids and terpenoids from Egletes viscosa.
PubMed:
Protective effect of ternatin, a flavonoid isolated from Egletes viscosa less., in experimental liver injury.
PubMed:
Molecular structures of two crystalline forms of the cyclic heptapeptide antibiotic ternatin, cyclo[-beta-OH-D-Leu-D-Ile-(NMe)Ala-(NMe)Leu-Leu-(NMe)Ala-D-(NMe)Ala-].
PubMed:
Anti-anaphylactic and anti-inflammatory effects of ternatin, a flavonoid isolated from Egletes viscosa Less.
PubMed:
[Chemical and chemotaxonomic studies of pterophyten. LXIV. Chemical studies on the contents of Sceptridium ternatum var. ternatum].