labdane F2
ent-8-hydroxylabda-13(16),14-diene
Identification
| Name | labdane F2 |
| IUPAC | (1R,2S,4aR,8aR)-2,5,5,8a-tetramethyl-1-(3-methylidenepent-4-enyl)-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol |
| CAS Number | 89900-49-2 |
| FDA UNII | Search |
| Molecular Formula | C20 H34 O |
| Molecular Weight | 290.49018000 |
| Nikkaji Number | J442.338K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 368.00 to 369.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 323.00 °F. TCC ( 161.40 °C. ) (est) |
| logP (o/w) | 6.741 (est) |
| Soluble in | water, 0.03955 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for labdane F2 usage levels up to | not for fragrance use. |
| Recommendation for labdane F2 flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
ent-8-
hydroxylabda-13(16),14-diene
(1R,2S,4aR,8aR)-2,5,5,8a-
tetramethyl-1-(3-methylidenepent-4-enyl)-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol
PubMed:
A novel diterpenoid labdane from Sideritis javalambrensis inhibits eicosanoid generation from stimulated macrophages but enhances arachidonate release.
PubMed:
Non-cytotoxic inhibition of macrophage eicosanoid biosynthesis and effects on leukocyte functions and reactive oxygen species of two novel anti-inflammatory plant diterpenoids.
PubMed:
Novel anti-inflammatory plant labdanes: comparison of in vitro properties with aspirin and indomethacin.