grosheimin

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4-beta-H-guaia-10(14),11(13)-dien-12-oic acid, 6-alpha,8-alpha-dihydroxy-3-oxo-, 12,6-lactone

CAS: 22489-66-3 C15 H18 O4 MW: 262.30526000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namegrosheimin
CAS Number22489-66-3
FDA UNIIML3SLU81RH
Molecular FormulaC15 H18 O4
Molecular Weight262.30526000
Nikkaji NumberJ15.323K

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 480.70 °C. @ 760.00 mm Hg (est)
Flash Point 362.00 °F. TCC ( 183.20 °C. ) (est)
logP (o/w) 0.270 (est)
Soluble in water, 5.68e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for grosheimin usage levels up tonot for fragrance use.
Recommendation for grosheimin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

cynara scolymus

Synonyms

azuleno(4,5-b)furan-2,8(3H,4H)-dione, octahydro-4-hydroxy-9-methyl-3,6-bis(methylene)-, (3aR-(3aalpha,4alpha,6aalpha,9alpha,9aalpha,9bbeta))- grossheimin 4-beta-H- guaia-10(14),11(13)-dien-12-oic acid, 6-alpha,8-alpha-dihydroxy-3-oxo-, 12,6-lactone (3aR,4S,6aR,9S,9aR,9bR)-4- hydroxy-9-methyl-3,6-dimethylidene-3a,4,5,6a,7,9,9a,9b-octahydroazuleno[4,5-b]furan-2,8-dione PubMed: Phytotoxicity of cardoon (Cynara cardunculus) allelochemicals on standard target species and weeds. PubMed: Studies on the constituents of whole plants of Youngia japonica. PubMed: Anti-hyperlipidemic sesquiterpenes and new sesquiterpene glycosides from the leaves of artichoke (Cynara scolymus L.): structure requirement and mode of action. PubMed: New cytotoxic guaianolides and derivatives from Grosheimia macrocephala. PubMed: Sesquiterpene lactones. 8. Cytostatic activity of grosheimin. PubMed: Sesquiterpene lactones. X. Isolation of grosheimin from the herb of Venidium decurens less.