tremetone
ethanone, 1-(2,3-dihydro-2-(1-methylethenyl)-5-benzofuranyl)-, (R)- (9CI)
Identification
| Name | tremetone |
| IUPAC | 1-[(2R)-2-prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl]ethanone |
| CAS Number | 4976-25-4 |
| FDA UNII | 451MA27V7H |
| Molecular Formula | C13 H14 O2 |
| Molecular Weight | 202.25298000 |
| Nikkaji Number | J8.791B |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Soluble in | water, 42.93 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for tremetone usage levels up to | not for fragrance use. |
| Recommendation for tremetone flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
(R)-1-(2,3-
dihydro-2-(1-methyl ethenyl)-5-benzofuranyl) ethanone
(R)-1-(2,3-
dihydro-2-(1-methylethenyl)-5-benzofuranyl)ethanone
ethanone, 1-(2,3-dihydro-2-(1-methylethenyl)-5-benzofuranyl)-, (R)- (9CI)
ketone, 2,3-dihydro-2-isopropenyl-5-benzofuranyl methyl (8CI)
1-[(2R)-2-
prop-1-en-2-yl-2,3-dihydro-1-benzofuran-5-yl]ethanone
tremeton
PubMed:
Toxicity of white snakeroot (Ageratina altissima) and chemical extracts of white snakeroot in goats.
PubMed:
A survey of tremetone, dehydrotremetone, and structurally related compounds in Isocoma spp. (goldenbush) in the southwestern United States.
PubMed:
Physiological and serum biochemical changes associated with rayless goldenrod (Isocoma pluriflora) poisoning in goats.
PubMed:
Experimental rayless goldenrod (Isocoma pluriflora) toxicosis in horses.
PubMed:
Chemical composition, antimicrobial and antioxidant properties of the volatile oil and methanol extract of Xenophyllum poposum.
PubMed:
Evaluation of analgesic activities of tremetone derivatives isolated from the Chilean altiplano medicine Parastrephia lepidophylla.
PubMed:
Evaluation of drying methods and toxicity of rayless goldenrod ( Isocoma pluriflora ) and white snakeroot ( Ageratina altissima ) in goats.
PubMed:
Development of a gas chromatography-mass spectrometry technique to diagnose white snakeroot (Ageratina altissima) poisoning in a cow.
PubMed:
Tremetone and structurally related compounds in white snakeroot ( Ageratina altissima ): a plant associated with trembles and milk sickness.
PubMed:
Quantitative method for the measurement of three benzofuran ketones in rayless goldenrod (Isocoma pluriflora) and white snakeroot (Ageratina altissima) by high-performance liquid chromatography (HPLC).
PubMed:
Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone.
PubMed:
Seasonal pasture myopathy in horses in the midwestern United States: 14 cases (1998-2005).
PubMed:
New dihydrobenzofurans and triterpenoids from roots of Microglossa pyrifolia.
PubMed:
Anti-inflammatory activity of acetophenones from Ophryosporus axilliflorus.
PubMed:
Growth-inhibitory activities of benzofuran and chromene derivatives toward Tenebrio molitor.
PubMed:
Phytogrowth-inhibitory and antifungal constituents of Helianthella quinquenervis.
PubMed:
Isolation of the major component in white snakeroot that is toxic after microsomal activation: possible explanation of sporadic toxicity of white snakeroot plants and extracts.
PubMed:
Natural plant toxicants in milk: a review.
PubMed:
Eupatoriopicrin 19-O-Linolenoate and Other Constituents from Eupatorium cannabium.
PubMed:
Weitere Phloroglucin- und alpha-Pyron-Derivate aus Helichrysum-Arten.
PubMed:
THE SYNTHESIS AND PHARMACOLOGICAL ACTION OF TREMETONE.