javanicin
1,4-naphthalenedione, 5,8-dihydroxy-6-methoxy-2-methyl-3-(2-oxopropyl)-
Identification
| Name | javanicin |
| IUPAC | 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione |
| CAS Number | 476-45-9 |
| FDA UNII | YNR51WFW2R |
| Molecular Formula | C15 H14 O6 |
| Molecular Weight | 290.27178000 |
| Nikkaji Number | J5.976E |
| Beilstein | 2296055 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 208.00 °C. @ 760.00 mm Hg |
| Boiling Point | 616.50 °C. @ 760.00 mm Hg (est) |
| Flash Point | 456.00 °F. TCC ( 235.70 °C. ) (est) |
| logP (o/w) | 1.510 (est) |
| Soluble in | water, 222.2 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 500 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for javanicin usage levels up to | not for fragrance use. |
| Recommendation for javanicin flavor usage levels up to | not for flavor use. |
BOC Sciences
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Potential Uses
Natural Occurrence
Synonyms
3-
acetonyl-5,8-dihydroxy-6-methoxy-2-methyl-1,4-naphthoquinone
5,8-
dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione
1,4-
naphthalenedione, 5,8-dihydroxy-6-methoxy-2-methyl-3-(2-oxopropyl)-
1,4-
naphthoquinone, 3-acetonyl-5,8-dihydroxy-6-methoxy-2-methyl-
PubMed:
Bioactive dihydronaphthoquinone derivatives from Fusarium solani.
PubMed:
Screening and evaluation of new inhibitors of hepatic glucose production.
PubMed:
Javanicin, an antibacterial naphthaquinone from an endophytic fungus of neem, Chloridium sp.
PubMed:
[Biosynthesis of naphthoquinone pigments by fungi of the genus Fusarium].
PubMed:
Fungal quinone pigments as oxidizers and inhibitors of mitochondrial NADH:ubiquinone reductase.
PubMed:
Studies on the constituents of Indonesian Picrasma javanica. III. Structures of new quassinoids, javanicins A, C and D.
PubMed:
NAPHTHAQUINONE BIOSYNTHESIS IN MOULDS: THE MECHANISM FOR FORMATION OF JAVANICIN.
PubMed:
Production of antibiotics by fungi; javanicin; an antibacterial pigment from Fusarium javanicum.