xanthohumol

(E)-1-(2,4- dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl)-3-(4-hydroxyphenyl)-2-propen-1-one (E)-1-[2,4- dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one 2- propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)- 2- propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)- PubMed: Pharmacokinetics of Prenylated Hop Phenols in Women Following Oral Administration of a Standardized Extract of Hops. PubMed: Hop-derived prenylflavonoids are substrates and inhibitors of the efflux transporter breast cancer resistance protein (BCRP/ABCG2). PubMed: Xanthohumol, a Prenylated Chalcone from Beer Hops, Acts as an α-Glucosidase Inhibitor in Vitro. PubMed: Xanthohumol modulates inflammation, oxidative stress, and angiogenesis in type 1 diabetic rat skin wound healing. PubMed: Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops. PubMed: Xanthohumol modulates the expression of osteoclast-specific genes during osteoclastogenesis in RAW264.7 cells. PubMed: Curcumin analogue identified as hyaluronan export inhibitor by virtual docking to the ABC transporter MRP5. PubMed: Electrochemical versus spectrophotometric assessment of antioxidant activity of hop (Humulus lupulus L.) products and individual compounds. PubMed: Simultaneous determination of prenylflavonoid and hop bitter acid in beer lee by HPLC-DAD-MS. PubMed: Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice. PubMed: Analytical condition setting a crucial step in the quantification of unstable polyphenols in acidic conditions: analyzing prenylflavanoids in biological samples by liquid chromatography-electrospray ionization triple quadruple mass spectrometry. PubMed: Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo. PubMed: Xanthohumol and it's emerging anti-neoplastic effects: beyond it's role in breast carcinomas. PubMed: Xanthohumol, a prenylated chalcone from Humulus lupulus L., inhibits cholesteryl ester transfer protein. PubMed: Prenylated chalcone xanthohumol associates with histones in breast cancer cells--a novel target identified by a monoclonal antibody. PubMed: Xanthohumol prevents carbon tetrachloride-induced acute liver injury in rats. PubMed: Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats. PubMed: Neuroprotective effects of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus), in ischemic stroke of rats. PubMed: Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration. PubMed: Protective effects of xanthohumol against the genotoxicity of heterocyclic aromatic amines MeIQx and PhIP in bacteria and in human hepatoma (HepG2) cells. PubMed: Xanthohumol uptake and intracellular kinetics in hepatocytes, hepatic stellate cells, and intestinal cells. PubMed: Xanthohumol-supplemented beer modulates angiogenesis and inflammation in a skin wound healing model. Involvement of local adipocytes. PubMed: Novel application of square-wave adsorptive-stripping voltammetry for the determination of xanthohumol in spent hops. PubMed: Computational analysis for hepatic safety signals of constituents present in botanical extracts widely used by women in the United States for treatment of menopausal symptoms. PubMed: Inhibitors of hyaluronan export from hops prevent osteoarthritic reactions. PubMed: Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ). PubMed: Disposition of hop prenylflavonoids in human breast tissue. PubMed: Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism. PubMed: Xanthohumol feeding does not impair organ function and homoeostasis in mice. PubMed: Recovery and metabolism of xanthohumol in germ-free and human microbiota-associated rats. PubMed: Selective inhibition of prenylated flavonoids from Sophora flavescens against BACE1 and cholinesterases. PubMed: Triggering of dendritic cell apoptosis by xanthohumol. PubMed: Determination of xanthohumol in beer based on cloud point extraction coupled with high performance liquid chromatography. PubMed: Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis. PubMed: Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes. PubMed: Inhibition of suicidal erythrocyte death by xanthohumol. PubMed: Xanthohumol from hop (Humulus lupulus L.) is an efficient inhibitor of monocyte chemoattractant protein-1 and tumor necrosis factor-alpha release in LPS-stimulated RAW 264.7 mouse macrophages and U937 human monocytes. PubMed: Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer. PubMed: LC-MS/MS quantitation of hop-derived bitter compounds in beer using the ECHO technique. PubMed: Xanthohumol influences preadipocyte differentiation: implication of antiproliferative and apoptotic effects. PubMed: Antimutagenicity of hops (Humulus lupulus L.): bioassay-directed fractionation and isolation of xanthohumol. PubMed: Enantioseparation of isoxanthohumol in beer by hydroxypropyl-gamma-cyclodextrin-modified micellar electrokinetic chromatography. PubMed: Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells. PubMed: Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women. PubMed: Relevance of organic farming and effect of climatological conditions on the formation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol in hop (Humulus lupulus L.). PubMed: Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity. PubMed: Optimization of conditions for supercritical fluid extraction of flavonoids from hops (Humulus lupulus L.). PubMed: Xanthohumol kills B-chronic lymphocytic leukemia cells by an apoptotic mechanism. PubMed: Xanthohumol, a new all-rounder? PubMed: Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice. PubMed: Enrichment of xanthohumol in the brewing process. PubMed: Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites. PubMed: A safety study of oral xanthohumol administration and its influence on fertility in Sprague Dawley rats. PubMed: In vitro phase II metabolism of xanthohumol by human UDP-glucuronosyltransferases and sulfotransferases. PubMed: Xanthohumol stimulates iodide uptake in rat thyroid-derived FRTL-5 cells. PubMed: Xanthohumol does not affect the composition of rat intestinal microbiota. PubMed: Biosynthetic (14)C-labelling of xanthohumol in hop cones. PubMed: Activation of proestrogens from hops (Humulus lupulus L.) by intestinal microbiota; conversion of isoxanthohumol into 8-prenylnaringenin. PubMed: Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). PubMed: Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway. PubMed: In vitro free radical and ONOO- scavengers from Sophora flavescens. PubMed: Cloning and molecular analysis of the regulatory factor HlMyb1 in hop (Humulus lupulus L.) and the potential of hop to produce bioactive prenylated flavonoids. PubMed: Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matrices. PubMed: Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.). PubMed: Identification, quantitation and biological activity of phytoestrogens in a dietary supplement for breast enhancement. PubMed: Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes. PubMed: Prenylflavonoids from hops inhibit the metabolic activation of the carcinogenic heterocyclic amine 2-amino-3-methylimidazo[4, 5-f]quinoline, mediated by cDNA-expressed human CYP1A2. PubMed: Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro. PubMed: Fate of xanthohumol and related prenylflavonoids from hops to beer. PubMed: Antiproliferative and cytotoxic effects of prenylated flavonoids from hops (Humulus lupulus) in human cancer cell lines.