kakkalide

4H-1- benzopyran-4-one, 5-hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-((6-O-b-D-xylopranosyl-b-D-glucopyranosyl)oxy)- 5- hydroxy-6-methoxy-3-(4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one PubMed: Screening for in vitro metabolites of kakkalide and irisolidone in human and rat intestinal bacteria by ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry. PubMed: Metabolic profile of irisolidone in rats obtained by ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry. PubMed: Metabolism and excretion of kakkalide and its metabolites in rat urine, bile, and feces as determined by HPLC/UV and LC/MS/MS. PubMed: Kakkalide ameliorates endothelial insulin resistance by suppressing reactive oxygen species-associated inflammation. PubMed: Cloning and characterization of ginsenoside Ra1-hydrolyzing beta-D-xylosidase from Bifidobacterium breve K-110. PubMed: Metabolism of ginsenoside Rb1 by human intestinal microflora and cloning of its metabolizing β-D-glucosidase from Bifidobacterium longum H-1. PubMed: Pharmacokinetics of kakkalide and its main metabolites in rat plasma determined by HPLC-DAD and LC-MSn. PubMed: Kakkalide and its metabolite irisolidone ameliorate carrageenan-induced inflammation in mice by inhibiting NF-κB pathway. PubMed: [Primary studies on chemical constituents from butanol extraction of the thorny elaeagnus leaf and their cytotoxicity]. PubMed: Simultaneous analysis of isoflavones and saponins in Pueraria flowers using HPLC coupled to an evaporative light scattering detector and isolation of a new isoflavone diglucoside. PubMed: Inhibitory activity of isoflavones of Pueraria flowers on nitric oxide production from lipopolysaccharide-activated primary rat microglia. PubMed: Isolation and identification of urinary metabolites of kakkalide in rats. PubMed: Cardioprotective effect of 'methylamine irisolidone', a new compound, in hypoxia/reoxygenation injury in cultured rat cardiac myocytes. PubMed: Aldose reductase inhibitors from Viola hondoensis W. Becker et H Boss. PubMed: Protective effect of irisolidone, a metabolite of kakkalide, against hydrogen peroxide induced cell damage via antioxidant effect. PubMed: Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana. PubMed: Anti-inflammatory mechanisms of isoflavone metabolites in lipopolysaccharide-stimulated microglial cells. PubMed: Estrogenic effect of main components kakkalide and tectoridin of Puerariae Flos and their metabolites. PubMed: Hepatoprotective effects of irisolidone on tert-butyl hyperoxide-induced liver injury. PubMed: Protective effects of kakkalide from Flos puerariae on ethanol-induced lethality and hepatic injury are dependent on its biotransformation by human intestinal microflora. PubMed: Study of substance changes in flowers of Pueraria thunbergiana Benth. during storage. PubMed: Effects of naturally occurring isoflavones on prostaglandin E2 production. PubMed: Pharmacological studies on Puerariae flos III: protective effects of kakkalide on ethanol-induced lethality and acute hepatic injury in mice.