idebenone

2,5-cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-

CAS: 58186-27-9 C19 H30 O5 MW: 338.44410000

Identification

Nameidebenone
IUPAC2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
CAS Number58186-27-9
FDA UNIIHB6PN45W4J
Molecular FormulaC19 H30 O5
Molecular Weight338.44410000
MDL NumberMFCD00274552
Nikkaji NumberJ22.706D
Beilstein2001459

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 497.30 °C. @ 760.00 mm Hg (est)
Flash Point 338.00 °F. TCC ( 170.10 °C. ) (est)
logP (o/w) 3.490 (est)
Soluble in water, 11.48 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesantioxidants

No sensory data available

Safety Information

Oral/Parenteral Toxicityunreported-mammal (species unspecified) LD50 > 1000 mg/kg
Dermal Toxicitysubcutaneous-mouse LD50 > 10000 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantioxidants
Recommendation for idebenone usage levels up tonot for fragrance use.
Recommendation for idebenone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

CV 2619 2,5- cyclohexadiene-1,4-dione, 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl- hydroxydecyl ubiquinone 6-(10- hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone 2-(10- hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione PubMed: Pharmacokinetic properties and metabolism of idebenone. PubMed: A comparison of the relative antioxidant potency of L-ergothioneine and idebenone. PubMed: Enhancement of nitroxide-reducing activity in rats after chronic administration of vitamin E, vitamin C, and idebenone examined by an in vivo electron spin resonance technique. PubMed: Idebenone improves learning and memory impairment induced by cholinergic or serotonergic dysfunction in rats. PubMed: Effects of idebenone on neurological deficits following cerebrovascular lesions in stroke-prone spontaneously hypertensive rats. PubMed: [Effect of idebenone on scopolamine-induced impairment of short-term memory in rats].