methyl lactoside
beta-D-glucopyranoside, methyl 4-O-beta-D-galactopyranosyl-
Identification
| Name | methyl lactoside |
| CAS Number | 7216-69-5 |
| FDA UNII | 868YEO5270 |
| Molecular Formula | C13 H24 O11 |
| Molecular Weight | 356.32548000 |
| MDL Number | MFCD00079443 |
| Nikkaji Number | J259.295I |
Regulatory
Physical Properties
| Food Chemicals Codex Listed | No |
| Boiling Point | 648.70 °C. @ 760.00 mm Hg (est) |
| Flash Point | 655.00 °F. TCC ( 346.10 °C. ) (est) |
| logP (o/w) | -3.160 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for methyl lactoside usage levels up to | not for fragrance use. |
| Recommendation for methyl lactoside flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2S,3R,4S,5R,6R)-2-[(2R,3S,4R,5R,6R)-4,5-
dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
beta-D-
glucopyranoside, methyl 4-O-beta-D-galactopyranosyl-
methyl alpha-lactoside
methyl-beta-D-lactoside
methyl-beta-dextro-lactoside
methyl-beta-lactoside
PubMed:
Methyl 4-O-beta-D-galactopyranosyl alpha-D-mannopyranoside methanol 0.375-solvate.
PubMed:
Methyl beta-allolactoside [methyl beta-D-galactopyranosyl-(1-->6)-beta-D-glucopyranoside] monohydrate.
PubMed:
Synthesis of Lewis X and three Lewis X trisaccharide analogues in which glucose and rhamnose replace N-acetylglucosamine and fucose, respectively.
PubMed:
DFT and NMR studies of 2JCOH, 3JHCOH, and 3JCCOH spin-couplings in saccharides: C-O torsional bias and H-bonding in aqueous solution.
PubMed:
Methyl 4-O-beta-L-galactopyranosyl-beta-D-glucopyranoside (methyl beta-L-lactoside).
PubMed:
Methyl 4-O-beta-D-galactopyranosyl alpha-D-glucopyranoside (methyl alpha-lactoside).
PubMed:
Synthesis of O-galactosyl aldoximes as potent LacNAc-mimetic galectin-3 inhibitors.
PubMed:
Aspergillus aculeatus beta-1,4-galactanase: substrate recognition and relations to other glycoside hydrolases in clan GH-A.
PubMed:
Different architecture of the combining site of the two chicken galectins revealed by chemical mapping studies with synthetic ligand derivatives.
PubMed:
Studies of the bound conformations of methyl alpha-lactoside and methyl beta-allolactoside to ricin B chain using transferred NOE experiments in the laboratory and rotating frames, assisted by molecular mechanics and dynamics calculations.
PubMed:
Substrate specificity of small-intestinal lactase: study of the steric effects and hydrogen bonds involved in enzyme-substrate interaction.
PubMed:
The use of CVFF and CFF91 force fields in conformational analysis of carbohydrate molecules. Comparison with AMBER molecular mechanics and dynamics calculations for methyl alpha-lactoside.
PubMed:
The use of the AMBER force field in conformational analysis of carbohydrate molecules: determination of the solution conformation of methyl alpha-lactoside by NMR spectroscopy, assisted by molecular mechanics and dynamics calculations.
PubMed:
Probing hydrogen-bonding interactions of bovine heart galectin-1 and methyl beta-lactoside by use of engineered ligands.
PubMed:
Involvement of the glucose moiety in the molecular recognition of methyl beta-lactoside by ricin: synthesis, conformational analysis, and binding studies of different derivatives at the C-3 region.
PubMed:
NMR spectroscopy of hydroxyl protons in supercooled carbohydrates.
PubMed:
Syntheses of all the possible monomethyl ethers and several deoxyhalo analogues of methyl beta-lactoside as ligands for the Ricinus communis lectins.
PubMed:
The conformation of the monomethyl ethers of methyl beta-lactoside in D2O and Me2SO-d6 solutions.
PubMed:
A convenient synthesis of N-acetyllactosamine derivatives from lactal.
PubMed:
Hydrogen-bonding pattern of methyl beta-lactoside binding to the Ricinus communis lectins.
PubMed:
The function of the 5-hydroxymethyl group of lactose in enzymatic hydrolysis with beta-galactosidase from E. coli.
PubMed:
Substrate specificity of small-intestinal lactase. Assessment of the role of the substrate hydroxyl groups.
PubMed:
Studies of the molecular recognition of synthetic methyl beta-lactoside analogues by Ricinus communis agglutinin.
PubMed:
The interaction of elderberry (Sambucus sieboldiana) bark lectin and sialyloligosaccharides as detected by 1H-NMR.
PubMed:
N.m.r. studies of the conformation of analogues of methyl beta-lactoside in methyl sulfoxide-d6.
PubMed:
Thio and epidithio derivatives of methyl beta-lactoside.
PubMed:
Studies on the molecular recognition of synthetic methyl beta-lactoside analogs by ricin, a cytotoxic plant lectin.
PubMed:
Derivatives of methyl beta-lactoside as substrates for and inhibitors of beta-D-galactosidase from E. coli.
PubMed:
Conformation of methyl beta-lactoside bound to the ricin B-chain: interpretation of transferred nuclear Overhauser effects facilitated by spin simulation and selective deuteration.
PubMed:
Effect of lactose derivatives on metastatic potential of B16 melanoma cells.
PubMed:
Glycolipid membrane surface structure: orientation, conformation, and motion of a disaccharide headgroup.
PubMed:
Binding of disaccharides by peanut agglutinin as studied by ultraviolet difference spectroscopy.
PubMed:
Carbon-13 nuclear magnetic resonance studies on lectin-carbohydrate interactions: binding of specifically carbon-13-labeled methyl beta-D-lactoside to peanut agglutinin.