eriodictyol
luteolin
Identification
| Name | eriodictyol |
| IUPAC | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one |
| CAS Number | 491-70-3 |
| EINECS | 207-741-0 |
| FDA UNII | KUX1ZNC9J2 |
| Molecular Formula | C15 H10 O6 |
| Molecular Weight | 286.23990000 |
| MDL Number | MFCD00017309 |
| Nikkaji Number | J1.554G |
| Beilstein | 0292084 |
| XlogP3 | 1.40 (est) |
Regulatory
Physical Properties
| Appearance | yellow crystalline powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 329.00 to 330.00 °C. @ 760.00 mm Hg |
| Boiling Point | 616.00 to 617.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 463.00 °F. TCC ( 239.50 °C. ) (est) |
| logP (o/w) | 2.695 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intraperitoneal-mouse LD50 180 mg/kg |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | cosmetic agents |
| Recommendation for eriodictyol usage levels up to | not for fragrance use. |
| baked goods | 20.00000 |
| beverages(nonalcoholic) | 20.00000 |
| beverages(alcoholic) | 20.00000 |
| breakfast cereal | 20.00000 |
| cheese | - |
| chewing gum | 50.00000 |
| condiments / relishes | - |
| confectionery froastings | 20.00000 |
| egg products | - |
| fats / oils | - |
| fish products | - |
| frozen dairy | 20.00000 |
| fruit ices | - |
| gelatins / puddings | 20.00000 |
| granulated sugar | - |
| gravies | - |
| hard candy | 20.00000 |
| imitation dairy | 20.00000 |
| instant coffee / tea | 20.00000 |
| jams / jellies | - |
| meat products | - |
| milk products | 20.00000 |
| nut products | - |
| other grains | - |
| poultry | - |
| processed fruits | - |
| processed vegetables | - |
| reconstituted vegetables | - |
| seasonings / flavors | 50.00000 |
| snack foods | 20.00000 |
| soft candy | - |
| soups | 20.00000 |
| sugar substitutes | 20.00000 |
| sweet sauces | 20.00000 |
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Potential Uses
Natural Occurrence
Synonyms
c.i. 75590
ci 75590
2-(3,4-
dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone
2-(3,4-
dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
2-(3,4-
dihydroxyphenyl)-5,7-dihydroxychromen-4-one
eriodictyol
luteolin
natural yellow 2
3',4',5,7-
tetrahydroxyflavanone
PubMed:
Identification of bisprenylated benzoic acid derivatives from yerba santa (Eriodictyon ssp.) using sensory-guided fractionation.
J-Stage:
Inhibitory Effect of Eriodictyol on IgE/Ag-Induced Type I Hypersensitivity
PubMed:
New bitter-masking compounds: hydroxylated benzoic acid amides of aromatic amines as structural analogues of homoeriodictyol.
PubMed:
Bioactive Compounds from Culinary Herbs Inhibit a Molecular Target for Type 2 Diabetes Management, Dipeptidyl Peptidase IV.
PubMed:
Feijoa sellowiana Berg fruit juice: anti-inflammatory effect and activity on superoxide anion generation.
PubMed:
Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis.
PubMed:
Hexanoyl-lysine as an oxidative-injured marker - application of development of functional food.
PubMed:
Food ingredient extracts of Cyclopia subternata (Honeybush): variation in phenolic composition and antioxidant capacity.
PubMed:
Screening natural antioxidants in peanut shell using DPPH-HPLC-DAD-TOF/MS methods.
PubMed:
Flavonoid deactivation of excited state flavins: reaction monitoring by mass spectrometry.
PubMed:
Analysis of hydrolyzable tannins and other phenolic compounds in emblic leafflower (Phyllanthus emblica L.) fruits by high performance liquid chromatography-electrospray ionization mass spectrometry.
PubMed:
Effect of eriodictyol on glucose uptake and insulin resistance in vitro.
PubMed:
Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis.
PubMed:
Neuroprotective and anti-inflammatory effects of flavonoids isolated from Rhus verniciflua in neuronal HT22 and microglial BV2 cell lines.
PubMed:
Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity.
PubMed:
Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads.
PubMed:
Bioactive polyphenols in leaves, stems, and berries of Saskatoon (Amelanchier alnifolia Nutt.) cultivars.
PubMed:
Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes.
PubMed:
Protective effect of Calamintha officinalis Moench leaves against alcohol-induced gastric mucosa injury in rats. Macroscopic, histologic and phytochemical analysis.
PubMed:
Functional expression of geraniol 10-hydroxylase reveals its dual function in the biosynthesis of terpenoid and phenylpropanoid.
PubMed:
Free fruit at workplace intervention increases total fruit intake: a validation study using 24âh dietary recall and urinary flavonoid excretion.
PubMed:
Depsides and other polar constituents from Origanum dictamnus L. and their in vitro antimicrobial activity in clinical strains.
PubMed:
Antioxidant activity and phenolic profile of pistachio (Pistacia vera L., variety Bronte) seeds and skins.
PubMed:
Phenolic compounds in cherry ( Prunus avium ) heartwood with a view to their use in cooperage.
PubMed:
Identification of bisprenylated benzoic acid derivatives from yerba santa (Eriodictyon ssp.) using sensory-guided fractionation.
PubMed:
Effect of pre-drying treatments and storage on color and phenolic composition of green honeybush (Cyclopia subternata) herbal tea.
PubMed:
Identification of compounds in adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) seed hull extracts that inhibit lipopolysaccharide-induced inflammation in RAW 264.7 macrophages.
PubMed:
Effects of phenolic compounds on the browning of cooked barley.
PubMed:
Bioavailability of C-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas.
PubMed:
Mangiferin and hesperidin metabolites are absorbed from the gastrointestinal tract of pigs after oral ingestion of a Cyclopia genistoides (honeybush tea) extract.
PubMed:
Aspalathin, a flavonoid in Aspalathus linearis (rooibos), is absorbed by pig intestine as a C-glycoside.
PubMed:
Analysis of flavonoids in propolis and Ginkgo biloba by micellar electrokinetic capillary chromatography.
PubMed:
Dietary flavonoid sources in Australian adults.
PubMed:
Characterization of phenolic compounds in rooibos tea.
PubMed:
Evaluation of natural antioxidants of Leuzea carthamoides as a result of a screening study of 88 plant extracts from the European Asteraceae and Cichoriaceae.
PubMed:
Alterations of flavonoid biosynthesis in young grapevine (Vitis vinifera L.) leaves, flowers, and berries induced by the dioxygenase inhibitor prohexadione-Ca.
PubMed:
Transepithelial transport of flavanone in intestinal Caco-2 cell monolayers.
PubMed:
Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry.
PubMed:
Identification and quantification of flavonoids of Mexican oregano (Lippia graveolens) by LC-DAD-ESI/MS analysis.
PubMed:
Kinetic model for the antiradical activity of the isolated p-catechol group in flavanone type structures using the free stable radical 2,2-diphenyl-1-picrylhydrazyl as the antiradical probe.
PubMed:
New bitter-masking compounds: hydroxylated benzoic acid amides of aromatic amines as structural analogues of homoeriodictyol.
PubMed:
Pistachio skin phenolics are destroyed by bleaching resulting in reduced antioxidative capacities.
PubMed:
Polar constituents from the aerial parts of Origanum vulgare L. Ssp. hirtum growing wild in Greece.
PubMed:
Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction.
PubMed:
Evaluation of bitter masking flavanones from Herba Santa (Eriodictyon californicum (H. and A.) Torr., Hydrophyllaceae).
PubMed:
Isolation and structure elucidation of phenolic antioxidants from Tamarind (Tamarindus indica L.) seeds and pericarp.
PubMed:
The pig caecum model: a suitable tool to study the intestinal metabolism of flavonoids.
PubMed:
Screening of free radical scavenging compounds in water extracts of Mentha samples using a postcolumn derivatization method.
PubMed:
Bioguided isolation and identification of the nonvolatile antioxidant compounds from fennel (Foeniculum vulgare Mill.) waste.
PubMed:
Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.
PubMed:
Inhibitory effect of some flavonoids on tumor necrosis factor-alpha production in lipopolysaccharide-stimulated mouse macrophage cell line J774.1.
PubMed:
Effect of the rootstock and interstock grafted in lemon tree (Citrus limon (L.) Burm.) on the flavonoid content of lemon juice.
PubMed:
Inhibitory effects of several flavonoids on E-selectin expression on human umbilical vein endothelial cells stimulated by tumor necrosis factor-alpha.
PubMed:
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of heteropolyflavan-3-ols and glucosylated heteropolyflavans in sorghum [Sorghum bicolor (L.) Moench].
PubMed:
In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids.
PubMed:
Identification and antioxidant activity of flavonoid metabolites in plasma and urine of eriocitrin-treated rats.
PubMed:
Japanese intake of flavonoids and isoflavonoids from foods.