apigenin dimethyl ether
5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone
Identification
| Name | apigenin dimethyl ether |
| IUPAC | 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)chromen-4-one |
| CAS Number | 5128-44-9 |
| EINECS | 225-867-4 |
| FDA UNII | Search |
| Molecular Formula | C17 H14 O5 |
| Molecular Weight | 298.29458000 |
| XlogP3 | 2.40 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 515.00 to 516.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 380.00 °F. TCC ( 193.30 °C. ) (est) |
| logP (o/w) | 3.444 (est) |
| Soluble in | water, 19.57 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for apigenin dimethyl ether usage levels up to | not for fragrance use. |
| Recommendation for apigenin dimethyl ether flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
apigenin dimethylether
genkwanin 4'-methyl ether
5-
hydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone
5-
hydroxy-7-methoxy-2-(4-methoxyphenyl)chromen-4-one
PubMed:
Isolation and characterization of an antifungal compound 5-hydroxy-7,4'-dimethoxyflavone from Combretum zeyheri.
PubMed:
A new bioactive monoterpene-flavonoid from Satureja khuzistanica.
PubMed:
Effect on oxidative stress, glucose uptake level and lipid droplet content by Apigenin 7, 4'-dimethyl ether isolated from Piper longum L.
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Novel C-xylosylflavones from the leaves and flowers of Iris gracilipes.
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Flavone composition and antihypercholesterolemic and antihyperglycemic activities of Chrysanthemum coronarium L.
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Further characterization of foliar flavonoids in Crossostephium chinense and their geographic variation.
PubMed:
[Phenolic compounds from Caesalpinia minax].
PubMed:
[Study on chemical constituents of Ixeris chinensis].
PubMed:
A new highly hydroxylated triterpene from Salvia atropatana Bunge.
PubMed:
A new triterpene from Salvia xanthocheila Boiss.
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Flavones and Flavone Glycosides from Salvia macrosiphon Boiss.
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The effect of "Teucrium polium L." extracts on insulin release from in situ isolated perfused rat pancreas in a newly modified isolation method: the role of Ca2+ and K+ channels.
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Anticomplementary principles of a Chinese multiherb remedy for the treatment and prevention of SARS.
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Antioxidant compounds of propolis determined by capillary electrophoresis-mass spectrometry.
PubMed:
[Studies on the flavonoids from whole herbs of Seriphidium terrae-albae].
PubMed:
[Studies on flavonoids from herb of Artemisia ordosica].
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[Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation].
PubMed:
External flavonoid aglycones from Veronica chamaedrys L. (Scrophulariaceae).
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The role of lipophilic and polar flavonoids in the classification of temperate members of the Anthemideae.
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Aquiledine and isoaquiledine, novel flavonoid alkaloids from Aquilegia ecalcarata.
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New prenylflavones from the leaves of Epimedium saggitatum.
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Chemical constituents of Artemisia arborescens and the effect of the aqueous extract on rat isolated smooth muscle.
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A biologically active lipophilic flavonol from Tanacetum parthenium.
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Methylated C-glycosylflavones as taxonomic markers in orchids of the subtribe Ornithocephalinae.
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Terpenoids from Salvia sclarea.
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Synthesis, characterization, and antibacterial activity of transition metal complexes with 5-hydroxy-7,4'-dimethoxyflavone.
PubMed:
A flavone with antiinflammatory activity from the roots of Rhus undulata.