5,7-dihydroxy-3,4'-dimethoxyflavone

CAS: 20869-95-8 C17 H14 O6 MW: 314.29378000

Identification

Nameermanin
IUPAC5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)chromen-4-one
CAS Number20869-95-8
EINECS244-093-8
FDA UNII850D90YJN3
Molecular FormulaC17 H14 O6
Molecular Weight314.29378000
MDL NumberMFCD00017440
Nikkaji NumberJ94.500E
XlogP32.50 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 552.00 °C. @ 760.00 mm Hg (est)
Flash Point 404.00 °F. TCC ( 206.90 °C. ) (est)
logP (o/w) 2.400 (est)
Soluble in water, 191.7 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for ermanin usage levels up tonot for fragrance use.
Recommendation for ermanin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

4H-1- benzopyran-4-one, 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)- chrysin, 3,4'-dimethoxy- 5,7- dihydroxy-3-methoxy-2-(4-methoxy-phenyl)-chromen-4-one 5,7- dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4-benzopyrone 5,7- dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one 5,7- dihydroxy-3-methoxy-2-(4-methoxyphenyl)chromen-4-one 5,7- dihydroxy-3,4'-dimethoxyflavone 3,4'- dimethoxychrysin PubMed: Targeting PknB, an eukaryotic-like serine/threonine protein kinase of Mycobacterium tuberculosis with phytomolecules. PubMed: New Sesquiterpenoids and Anti-Platelet Aggregation Constituents from the Rhizomes of Curcuma zedoaria. PubMed: Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla. PubMed: In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae). PubMed: Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum. PubMed: Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti-inflammatory mediators in LPS-stimulated mouse peritoneal macrophages. PubMed: Phytotoxic compounds from Flourensia cernua. PubMed: Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia. PubMed: Effects of compounds extracted from Tanacetum microphyllum on arachidonic acid metabolism in cellular systems. PubMed: Isolation of two flavonoids from Tanacetum microphyllum as PMA-induced ear edema inhibitors.