ermanin
5,7-dihydroxy-3,4'-dimethoxyflavone
Identification
| Name | ermanin |
| IUPAC | 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)chromen-4-one |
| CAS Number | 20869-95-8 |
| EINECS | 244-093-8 |
| FDA UNII | 850D90YJN3 |
| Molecular Formula | C17 H14 O6 |
| Molecular Weight | 314.29378000 |
| MDL Number | MFCD00017440 |
| Nikkaji Number | J94.500E |
| XlogP3 | 2.50 (est) |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 552.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 404.00 °F. TCC ( 206.90 °C. ) (est) |
| logP (o/w) | 2.400 (est) |
| Soluble in | water, 191.7 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for ermanin usage levels up to | not for fragrance use. |
| Recommendation for ermanin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4H-1-
benzopyran-4-one, 5,7-dihydroxy-3-methoxy-2-(4-methoxyphenyl)-
chrysin, 3,4'-dimethoxy-
5,7-
dihydroxy-3-methoxy-2-(4-methoxy-phenyl)-chromen-4-one
5,7-
dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4-benzopyrone
5,7-
dihydroxy-3-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
5,7-
dihydroxy-3-methoxy-2-(4-methoxyphenyl)chromen-4-one
5,7-
dihydroxy-3,4'-dimethoxyflavone
3,4'-
dimethoxychrysin
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Targeting PknB, an eukaryotic-like serine/threonine protein kinase of Mycobacterium tuberculosis with phytomolecules.
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New Sesquiterpenoids and Anti-Platelet Aggregation Constituents from the Rhizomes of Curcuma zedoaria.
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Anti-HIV-1 diterpenoids from leaves and twigs of Polyalthia sclerophylla.
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In vitro antileishmanial, antiplasmodial and cytotoxic activities of phenolics and triterpenoids from Baccharis dracunculifolia D. C. (Asteraceae).
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Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids isolated from Tanacetum microphyllum.
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Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti-inflammatory mediators in LPS-stimulated mouse peritoneal macrophages.
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Phytotoxic compounds from Flourensia cernua.
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Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia.
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Effects of compounds extracted from Tanacetum microphyllum on arachidonic acid metabolism in cellular systems.
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Isolation of two flavonoids from Tanacetum microphyllum as PMA-induced ear edema inhibitors.