oxypeucadanin
7H-furo[3,2-g][1]benzopyran-7-one, 4-[(3,3-dimethyloxiranyl)methoxy]-
Identification
| Name | oxypeucadanin |
| IUPAC | 4-[(3,3-dimethyloxiran-2-yl)methoxy]furo[3,2-g]chromen-7-one |
| CAS Number | 737-52-0 |
| FDA UNII | AL8MV76MSB |
| Molecular Formula | C16 H14 O5 |
| Molecular Weight | 286.28358000 |
| Nikkaji Number | J277.665K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 469.50 °C. @ 760.00 mm Hg (est) |
| Flash Point | 460.00 °F. TCC ( 237.70 °C. ) (est) |
| logP (o/w) | 1.740 (est) |
| Soluble in | water, 97.9 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for oxypeucadanin usage levels up to | not for fragrance use. |
| Recommendation for oxypeucadanin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
4-((3,3-
dimethyl oxiranyl)methoxy)-7H-furo(3,2-g)(1)benzopyran-7-one
4-[(3,3-
dimethyl-2-oxiranyl)methoxy]-7H-furo[3,2-g]chromen-7-one
4-(3,3-
dimethyl-oxiranylmethoxy)-furo[3,2-g]chromen-7-one
4-[(3,3-
dimethyloxiran-2-yl)methoxy]furo[3,2-g]chromen-7-one
7H-
furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)-
7H-
furo[3,2-g][1]benzopyran-7-one, 4-[(3,3-dimethyloxiranyl)methoxy]-
oxy
peucedanin
oxy
peucedarin
PubMed:
[Chemical constituents contained in seeds of Notopterygium franchetii].
PubMed:
Development of a rapid resolution liquid chromatographic method combined with chemometrics for quality control of Angelicae dahuricae radix.
PubMed:
Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins.
PubMed:
Effects of oxypeucedanin on global gene expression and MAPK signaling pathway in mouse neuroblastoma Neuro-2A cells.
PubMed:
Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study.
PubMed:
An efficient approach for the isolation, identification and evaluation of antimicrobial plant components on an analytical scale, demonstrated by the example of Radix imperatoriae.
PubMed:
Coumarins from Angelica lucida L.--antibacterial activities.
PubMed:
Simultaneous determination of five coumarins in Angelicae dahuricae Radix by HPLC/UV and LC-ESI-MS/MS.
PubMed:
Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells.
PubMed:
High-performance liquid chromatographic method for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma.
PubMed:
Preparative isolation of imperatorin, oxypeucedanin and isoimperatorin from traditional Chinese herb "bai zhi"Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook using multidimensional high-speed counter-current chromatography.
PubMed:
Nonvolatiles of commercial lime and grapefruit oils separated by high-speed countercurrent chromatography.
PubMed:
The antimycobacterial constituents of dill (Anethum graveolens).
PubMed:
[Determination of coumarins content in Radix Angelicae dahuricae by HPLC and UV].
PubMed:
Effects of oxypeucedanin on hKv1.5 and action potential duration.
PubMed:
Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas.
PubMed:
Furocoumarins from Angelica dahurica with hepatoprotective activity on tacrine-induced cytotoxicity in Hep G2 cells.
PubMed:
Inhibitors of 5alpha -reductase type I in LNCaP cells from the roots of Angelica koreana.
PubMed:
Simultaneous determination of byak-angelicin and oxypeucedanin hydrate in rat plasma by column-switching high-performance liquid chromatography with ultraviolet detection.
PubMed:
[Determination of coumarins in radix Angelicae Dahuricae before and after processing].
PubMed:
[Reverse-phase HPLC determination of coumarins in the traditional Chinese drug bai-zhi (Angelica dahurica forma bai-zhi)].
PubMed:
[Pharmacological studies on oxypeucedanin].
PubMed:
Furanocoumarins from Maquira calophylla.
PubMed:
Structure-activity relationship in the toxicity of some naturally occurring coumarins-chalepin, imperatorin and oxypeucedanine.