oxypeucadanin

7H-furo[3,2-g][1]benzopyran-7-one, 4-[(3,3-dimethyloxiranyl)methoxy]-

CAS: 737-52-0 C16 H14 O5 MW: 286.28358000

Identification

Nameoxypeucadanin
IUPAC4-[(3,3-dimethyloxiran-2-yl)methoxy]furo[3,2-g]chromen-7-one
CAS Number737-52-0
FDA UNIIAL8MV76MSB
Molecular FormulaC16 H14 O5
Molecular Weight286.28358000
Nikkaji NumberJ277.665K

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 469.50 °C. @ 760.00 mm Hg (est)
Flash Point 460.00 °F. TCC ( 237.70 °C. ) (est)
logP (o/w) 1.740 (est)
Soluble in water, 97.9 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for oxypeucadanin usage levels up tonot for fragrance use.
Recommendation for oxypeucadanin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

carrot root lemon fruit oil lemon oil parsley fruit parsley leaf

Synonyms

4-((3,3- dimethyl oxiranyl)methoxy)-7H-furo(3,2-g)(1)benzopyran-7-one 4-[(3,3- dimethyl-2-oxiranyl)methoxy]-7H-furo[3,2-g]chromen-7-one 4-(3,3- dimethyl-oxiranylmethoxy)-furo[3,2-g]chromen-7-one 4-[(3,3- dimethyloxiran-2-yl)methoxy]furo[3,2-g]chromen-7-one 7H- furo(3,2-g)(1)benzopyran-7-one, 4-((3,3-dimethyloxiranyl)methoxy)- 7H- furo[3,2-g][1]benzopyran-7-one, 4-[(3,3-dimethyloxiranyl)methoxy]- oxy peucedanin oxy peucedarin PubMed: [Chemical constituents contained in seeds of Notopterygium franchetii]. PubMed: Development of a rapid resolution liquid chromatographic method combined with chemometrics for quality control of Angelicae dahuricae radix. PubMed: Insights into structure-activity relationship of GABAA receptor modulating coumarins and furanocoumarins. PubMed: Effects of oxypeucedanin on global gene expression and MAPK signaling pathway in mouse neuroblastoma Neuro-2A cells. PubMed: Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study. PubMed: An efficient approach for the isolation, identification and evaluation of antimicrobial plant components on an analytical scale, demonstrated by the example of Radix imperatoriae. PubMed: Coumarins from Angelica lucida L.--antibacterial activities. PubMed: Simultaneous determination of five coumarins in Angelicae dahuricae Radix by HPLC/UV and LC-ESI-MS/MS. PubMed: Anti-tumor activity of oxypeucedanin from Ostericum koreanum against human prostate carcinoma DU145 cells. PubMed: High-performance liquid chromatographic method for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma. PubMed: Preparative isolation of imperatorin, oxypeucedanin and isoimperatorin from traditional Chinese herb "bai zhi"Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook using multidimensional high-speed counter-current chromatography. PubMed: Nonvolatiles of commercial lime and grapefruit oils separated by high-speed countercurrent chromatography. PubMed: The antimycobacterial constituents of dill (Anethum graveolens). PubMed: [Determination of coumarins content in Radix Angelicae dahuricae by HPLC and UV]. PubMed: Effects of oxypeucedanin on hKv1.5 and action potential duration. PubMed: Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas. PubMed: Furocoumarins from Angelica dahurica with hepatoprotective activity on tacrine-induced cytotoxicity in Hep G2 cells. PubMed: Inhibitors of 5alpha -reductase type I in LNCaP cells from the roots of Angelica koreana. PubMed: Simultaneous determination of byak-angelicin and oxypeucedanin hydrate in rat plasma by column-switching high-performance liquid chromatography with ultraviolet detection. PubMed: [Determination of coumarins in radix Angelicae Dahuricae before and after processing]. PubMed: [Reverse-phase HPLC determination of coumarins in the traditional Chinese drug bai-zhi (Angelica dahurica forma bai-zhi)]. PubMed: [Pharmacological studies on oxypeucedanin]. PubMed: Furanocoumarins from Maquira calophylla. PubMed: Structure-activity relationship in the toxicity of some naturally occurring coumarins-chalepin, imperatorin and oxypeucedanine.