halazuchrome B

valtrate

CAS: 18296-44-1 C22 H30 O8 MW: 422.47470000

Identification

Namehalazuchrome B
IUPAC[(1S,6S,7R,7aS)-4-(acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-methylbutanoate
CAS Number18296-44-1
EINECS242-174-2
FDA UNIIL3JQ035X9B
Molecular FormulaC22 H30 O8
Molecular Weight422.47470000
Nikkaji NumberJ14.326J

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 8.463 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for halazuchrome B usage levels up tonot for fragrance use.
Recommendation for halazuchrome B flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

radix valerianae mexicanae

Synonyms

4- acetoxymethyl-1,6,7,7a-tetrahydro-1,6-bis(isovaleryloxy)cyclopenta(c)pyran-7-spiro-2'-oxiran [(1S,6S,7R,7aS)-4-( acetyloxymethyl)-1-(3-methylbutanoyloxy)spiro[6,7a-dihydro-1H-cyclopenta[c]pyran-7,2'-oxirane]-6-yl] 3-methylbutanoate baldrisedon 1,7a- dihydro-1,6-dihydroxyspiro(cyclopenta(c)pyran-7-(6H),2'-oxirane)-4-methanol 4-acetate 1,6-diisovalerate valepotriate valtrate valtratum PubMed: Flexible and powerful strategy for qualitative and quantitative analysis of valepotriates in Valeriana jatamansi Jones using high-performance liquid chromatography with linear ion trap Orbitrap mass spectrometry. PubMed: Three minor valepotriate isomers from Valeriana jatamansi and their cytotoxicity. PubMed: Mass spectrometric profiling of valepotriates possessing various acyloxy groups from Valeriana jatamansi. PubMed: Development of a LC-MS-MS Method for Quantification of Valtrate and Its Application to Pharmacokinetic Study. PubMed: Nucleo-cytoplasmic transport as a therapeutic target of cancer. PubMed: The anxiolytic effects of valtrate in rats involves changes of corticosterone levels. PubMed: [Mass spectrum characterization of five valepotriates by electrospray ionization tandem mass spectrometry]. PubMed: Valeriana jatamansi constituent IVHD-valtrate as a novel therapeutic agent to human ovarian cancer: in vitro and in vivo activities and mechanisms. PubMed: Nuclear export of proteins and drug resistance in cancer. PubMed: Effect of storage time and conditions on the diene valepotriates content of the extract of Valeriana glechomifolia obtained by supercritical carbon dioxide. PubMed: In vitro effect of valepotriates isolated from Valeriana glechomifolia on rat P-type ATPases. PubMed: Controlling protein transport by small molecules. PubMed: Anti-influenza viral effects of novel nuclear export inhibitors from Valerianae Radix and Alpinia galanga. PubMed: Concise synthesis of 5,6-dihydrovaltrate leading to enhanced Rev-export inhibitory congener. PubMed: Bioisostere of valtrate, anti-HIV principle by inhibition for nuclear export of Rev. PubMed: [Study on quality specification of Rhizoma et Radix Valeriana Jatamansi]. PubMed: Sorbifolivaltrates A-D, diene valepotriates from Valeriana sorbifolia(1). PubMed: A new iridoid tetraester from Valeriana jatamansi. PubMed: Preserved pharmacological activity of hepatocytes-treated extracts of valerian and St. John's wort. PubMed: Control of development and valepotriate production by auxins in micropropagated Valeriana glechomifolia. PubMed: New Rev-transport inhibitor with anti-HIV activity from Valerianae Radix. PubMed: Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial. PubMed: Quantitative determination of valepotriates from Valeriana native to South Brazil. PubMed: Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp.procera. PubMed: Cytotoxic potential of valerian constituents and valerian tinctures. PubMed: Production of valepotriates by hairy root cultures of Centranthus ruber DC. PubMed: Effect of valepotriates on the behavior of rats in the elevated plus-maze during diazepam withdrawal. PubMed: Effects of a prolonged administration of valepotriates in rats on the mothers and their offspring. PubMed: High-yield production of valepotriates by hairy root cultures of Valeriana officnalis L. var. sambucifolia Mikan. PubMed: Valerian-derived sedative agents. I. On the structure and spectral assignment of the constituents of valmane using the selective INEPT nuclear magnetic resonance technique. PubMed: Effects of thiol compounds versus the cytotoxicity of valepotriates on cultured hepatoma cells. PubMed: Bacterial mutagenicity of the tranquilizing constituents of Valerianaceae roots. PubMed: In vitro mutagenicity of valepotriates. PubMed: The Structure of New Valepotriates from Tissue Cultures of Valeriana wallichii. PubMed: Influence of valtrate/isovaltrate on the hematopoiesis and metabolic liver activity in mice in vivo. PubMed: [In vivo effect of valtrate/isovaltrate on bone marrow cells and the metabolic activity of the liver in mice]. PubMed: [The effects of valtrate on the EEG of the isolated, perfused rat brain]. PubMed: [Effect of valeprotriate on spontaneous motor activity in mice]. PubMed: Valepotriate content in different in vitro cultures of Valerianaceae and characterization of Valeriana officinalis L. callus during a growth period. PubMed: Antispasmodic effects of valeriana compounds: an in-vivo and in-vitro study on the guinea-pig ileum. PubMed: Separation of valtrate and isovaltrate by means of preparative liquid chromatography. PubMed: HPCL Separation and quantitative determination of valepotriates from Valeriana kilimandascharica. PubMed: [Autonomic disorders in general practice. Possibilities of drug therapy with Baldrisedon]. PubMed: [Pharmacological studies of Centranthus ruber]. PubMed: [Determination of valtrate in drugs].