nootkatol

2,3,4,4a,5,6,7,8-octahydro-4,4a-dimethyl-6-(1-methylvinyl)-2-naphthol

CAS: 53643-07-5 C15 H24 O MW: 220.35548000

Identification

Namenootkatol
IUPAC4,4a-dimethyl-6-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-naphthalen-2-ol
CAS Number53643-07-5
EINECS258-681-7
FDA UNIISearch
Molecular FormulaC15 H24 O
Molecular Weight220.35548000
Nikkaji NumberJ296.007I

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 316.00 to 317.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000033 mmHg @ 25.00 °C. (est)
Flash Point 268.00 °F. TCC ( 131.20 °C. ) (est)
logP (o/w) 4.680 (est)
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for nootkatol usage levels up tonot for fragrance use.
Recommendation for nootkatol flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

alpinia oxyphylla Miquel cherry brazilian cherry leaf orange fruit

Synonyms

4,4a- dimethyl-6-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-naphthalen-2-ol 2,3,4,4a,5,6,7,8- octahydro-4,4a-dimethyl-6-(1-methylvinyl)-2-naphthol PubMed: Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris. PubMed: Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris. PubMed: Valencene oxidase CYP706M1 from Alaska cedar (Callitropsis nootkatensis). PubMed: Challenges and pitfalls of P450-dependent (+)-valencene bioconversion by Saccharomyces cerevisiae. PubMed: Constituents of south Indian vetiver oils. PubMed: Biologically important eremophilane sesquiterpenes from alaska cedar heartwood essential oil and their semi-synthetic derivatives. PubMed: A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. PubMed: Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system. PubMed: Antimicrobial activity of extractable conifer heartwood compounds toward Phytophthora ramorum. PubMed: Changes in heartwood chemistry of dead yellow-cedar trees that remain standing for 80 years or more in southeast Alaska. PubMed: Bioconversion of (+)-valencene in submerged cultures of the ascomycete Chaetomium globosum. PubMed: Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3. PubMed: Structural determination of nootkatol, a new sesquiterpene isolated from Alpinia oxyphylla Miquel possessing calcium-antagonistic activity. PubMed: Regioselective biotransformation of valencene in cell suspension cultures of Citrus sp.