magnosalin

benzene, 1,1'-(3,4-dimethyl-1,2-cyclobutanediyl)bis(2,4,5-trimethoxy-

CAS: 73036-51-8 C24 H32 O6 MW: 416.51424000

Identification

Namemagnosalin
CAS Number73036-51-8
FDA UNIISearch
Molecular FormulaC24 H32 O6
Molecular Weight416.51424000
Nikkaji NumberJ1.311.075A

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 499.20 °C. @ 760.00 mm Hg (est)
Flash Point 382.00 °F. TCC ( 194.20 °C. ) (est)
logP (o/w) 5.526 (est)
Soluble in water, 0.02977 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for magnosalin usage levels up tonot for fragrance use.
Recommendation for magnosalin flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

cubeb

Synonyms

benzene, 1,1'-(3,4-dimethyl-1,2-cyclobutanediyl)bis(2,4,5-trimethoxy- 1-[2,3- dimethyl-4-(2,4,5-trimethoxyphenyl)cyclobutyl]-2,4,5-trimethoxybenzene heterotropan PubMed: Synthesis of cyclobutane lignans via an organic single electron oxidant-electron relay system. PubMed: Two neolignans from Perilla frutescens and their inhibition of nitric oxide synthase and tumor necrosis factor-alpha expression in murine macrophage cell line RAW 264.7. PubMed: Synthesis of a magnosalin derivative, 4-(3,4,5-trimethoxyphenyl)-6-(2,4,5-trimethoxyphenyl)-2-diethylaminopyrimidine, and the anti-angiogenic and anti-rheumatic effect on mice by oral administration. PubMed: Lignans from Mosla scabra. PubMed: Inhibitory effects of anti-rheumatic drugs containing magnosalin, a compound from 'Shin-i' (Flos magnoliae), on the proliferation of synovial cells in rheumatoid arthritis models. PubMed: Inhibitory effect of magnosalin derived from Flos magnoliae on tube formation of rat vascular endothelial cells during the angiogenic process. PubMed: Inhibitory effects of magnoshinin and magnosalin, compounds from "Shin-i" (Flos magnoliae), on the competence and progression phases in proliferation of subcultured rat aortic endothelial cells. PubMed: Selective inhibition by magnosalin and magnoshinin, compounds from "Shin-i" (Flos magnoliae), of adjuvant-induced angiogenesis and granuloma formation in the mouse pouch. PubMed: Selective inhibition by magnosalin and magnoshinin, compounds from 'shin-i' (Flos magnoliae), of adjuvant-induced angiogenesis and granuloma formation in the mouse pouch. PubMed: Anti-Inflammatory Effect of Neolignans Newly Isolated from the Crude Drug "Shin-i" (Flos Magnoliae).