magnosalin
benzene, 1,1'-(3,4-dimethyl-1,2-cyclobutanediyl)bis(2,4,5-trimethoxy-
Identification
| Name | magnosalin |
| CAS Number | 73036-51-8 |
| FDA UNII | Search |
| Molecular Formula | C24 H32 O6 |
| Molecular Weight | 416.51424000 |
| Nikkaji Number | J1.311.075A |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 499.20 °C. @ 760.00 mm Hg (est) |
| Flash Point | 382.00 °F. TCC ( 194.20 °C. ) (est) |
| logP (o/w) | 5.526 (est) |
| Soluble in | water, 0.02977 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for magnosalin usage levels up to | not for fragrance use. |
| Recommendation for magnosalin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
benzene, 1,1'-(3,4-dimethyl-1,2-cyclobutanediyl)bis(2,4,5-trimethoxy-
1-[2,3-
dimethyl-4-(2,4,5-trimethoxyphenyl)cyclobutyl]-2,4,5-trimethoxybenzene
heterotropan
PubMed:
Synthesis of cyclobutane lignans via an organic single electron oxidant-electron relay system.
PubMed:
Two neolignans from Perilla frutescens and their inhibition of nitric oxide synthase and tumor necrosis factor-alpha expression in murine macrophage cell line RAW 264.7.
PubMed:
Synthesis of a magnosalin derivative, 4-(3,4,5-trimethoxyphenyl)-6-(2,4,5-trimethoxyphenyl)-2-diethylaminopyrimidine, and the anti-angiogenic and anti-rheumatic effect on mice by oral administration.
PubMed:
Lignans from Mosla scabra.
PubMed:
Inhibitory effects of anti-rheumatic drugs containing magnosalin, a compound from 'Shin-i' (Flos magnoliae), on the proliferation of synovial cells in rheumatoid arthritis models.
PubMed:
Inhibitory effect of magnosalin derived from Flos magnoliae on tube formation of rat vascular endothelial cells during the angiogenic process.
PubMed:
Inhibitory effects of magnoshinin and magnosalin, compounds from "Shin-i" (Flos magnoliae), on the competence and progression phases in proliferation of subcultured rat aortic endothelial cells.
PubMed:
Selective inhibition by magnosalin and magnoshinin, compounds from "Shin-i" (Flos magnoliae), of adjuvant-induced angiogenesis and granuloma formation in the mouse pouch.
PubMed:
Selective inhibition by magnosalin and magnoshinin, compounds from 'shin-i' (Flos magnoliae), of adjuvant-induced angiogenesis and granuloma formation in the mouse pouch.
PubMed:
Anti-Inflammatory Effect of Neolignans Newly Isolated from the Crude Drug "Shin-i" (Flos Magnoliae).