atractylon

3,8a-dimethyl-5-methylene-4,4a,6,7,8,9-hexahydrobenzo(f)benzofuran

CAS: 6989-21-5 C15 H20 O MW: 216.32360000

Identification

Nameatractylon
CAS Number6989-21-5
FDA UNIISearch
Molecular FormulaC15 H20 O
Molecular Weight216.32360000
MDL NumberMFCD00210477
Nikkaji NumberJ356.270K

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 285.00 to 286.00 °C. @ 760.00 mm Hg
Flash Point 251.00 °F. TCC ( 121.67 °C. )
logP (o/w) 5.570
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for atractylon usage levels up tonot for fragrance use.
Recommendation for atractylon flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

atractylodes macrocephala protium heptaphyllum (aubl.) march leaf oil brazil @ 1.00% Data

Synonyms

atractylone 3,8a- dimethyl-5-methylene-4,4a,6,7,8,9-hexahydrobenzo(f)benzofuran 3,8a- dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzoxole (4aS-trans)-4,4a,5,6,7,8,8a,9- octahydro-3,8a-dimethyl-5-methylene naphtho(2,3-b)furan (4aS,8aR)-3,8a- dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran PubMed: Differentiation of essential oils in Atractylodes lancea and Atractylodes koreana by gas chromatography with mass spectrometry. PubMed: Antiviral activities of atractylon from Atractylodis Rhizoma. PubMed: Quantitative and fingerprinting analysis of Atractylodes rhizome based on gas chromatography with flame ionization detection combined with chemometrics. PubMed: Anti-inflammatory and Antinociceptive Constituents of Atractylodes japonica Koidzumi. PubMed: Traditional herbal medicine for the control of tropical diseases. PubMed: Chemical composition and major odor-active compounds of essential oil from PINELLIA TUBER (dried rhizome of Pinellia ternata) as crude drug. PubMed: [Verification of processing theory of "reducing ketone and dryness, and increasing ester and effect" for bran-fried atractylodes]. PubMed: [UFLC/Q-TOF-MS based analysis on material base of atractylodis macrocephalae rhizoma stir-fried with wheat bran]. PubMed: [Screening and identification of an endophytic fungus from Atractylodes lancea which utilizes volatile oil selectively]. PubMed: [Study on processing technology and processing principles of atractrylodis macrocephalae rhizoma]. PubMed: Anti-Oxidative Abilities of Essential Oils from Atractylodes ovata Rhizome. PubMed: Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis. PubMed: Gastroprotective activity of atractylenolide III from Atractylodes ovata on ethanol-induced gastric ulcer in vitro and in vivo. PubMed: Quantitative determination of atractylon in Atractylodis Rhizoma and Atractylodis Lanceae Rhizoma by 1H-NMR spectroscopy. PubMed: Intestinal permeability of sesquiterpenes in the caco-2 cell monolayer model. PubMed: Identification of volatile compounds of Atractylode lancea rhizoma using supercritical fluid extraction and GC-MS. PubMed: [Simultaneous determination of atractylenolide III, atractylenolide I and atractylon in Artactylodis macrocephala using microbore liquid chromatography]. PubMed: [Studies on volatile oil from Atractylodes macrocephala with different distill methods]. PubMed: [Fingerprint of volatile oil of Atractylodes lancea by GC-MS]. PubMed: Toxicity of atractylon and atractylenolide III Identified in Atractylodes ovata rhizome to Dermatophagoides farinae and Dermatophagoides pteronyssinus. PubMed: Analysis of the sesquiterpenoids in processed Atractylodis Rhizoma. PubMed: Preparative isolation and purification of atractylon and atractylenolide III from the Chinese medicinal plant atractylodes macrocephala by high-speed counter-current chromatography. PubMed: Composition of the essential oil of rootstock from Cimicifuga simplex. PubMed: Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (+/-)-biatractylolide and (+/-)-biepiasterolide. PubMed: Cytotoxic activity of sesquiterpenoids from Atractylodes ovata on leukemia cell lines. PubMed: 5-Lipoxygenase and cyclooxygenase-1 inhibitory active compounds from Atractylodes lancea. PubMed: Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants. PubMed: A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis. PubMed: [Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes]. PubMed: Restriction fragment length polymorphisms of rDNA and variation of essential oil composition in Atractylodes plants. PubMed: Specific inhibition of Na+,K(+)-ATPase activity by atractylon, a major component of byaku-jutsu, by interaction with enzyme in the E2 state. PubMed: Inhibitory effect of atractylon on tert-butyl hydroperoxide induced DNA damage and hepatic toxicity in rat hepatocytes. PubMed: Atractylodis Rhizoma extract and its component, atractylon, inhibit tumor promotion in mouse skin two-stage carcinogenesis. PubMed: [Imaging analysis of antiulcer action and the active constituent of Atractylodis rhizoma]. PubMed: Clonal Propagation of Atractylodes japonica and A. ovata by Tip Tissue Culture and the Atractylon Content of Clonally Propagated Plants. PubMed: [Exploration on baking conditions for Atractylodes macrocephala Kloidz in qiweibaizhusan bags]. PubMed: Mechanism of antihepatotoxic activity of atractylon, I: Effect on free radical generation and lipid peroxidation. PubMed: Antihepatotoxic principles of Atractylodes rhizomes. PubMed: STUDIES ON THE CONSTITUENTS OF ATRACTYLODES. IX. STRUCTURE AND AUTOXIDATION OF ATRACTYLON. PubMed: Structure and autoxidation of atractylon.