atractylon
3,8a-dimethyl-5-methylene-4,4a,6,7,8,9-hexahydrobenzo(f)benzofuran
Identification
| Name | atractylon |
| CAS Number | 6989-21-5 |
| FDA UNII | Search |
| Molecular Formula | C15 H20 O |
| Molecular Weight | 216.32360000 |
| MDL Number | MFCD00210477 |
| Nikkaji Number | J356.270K |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 285.00 to 286.00 °C. @ 760.00 mm Hg |
| Flash Point | 251.00 °F. TCC ( 121.67 °C. ) |
| logP (o/w) | 5.570 |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for atractylon usage levels up to | not for fragrance use. |
| Recommendation for atractylon flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
atractylone
3,8a-
dimethyl-5-methylene-4,4a,6,7,8,9-hexahydrobenzo(f)benzofuran
3,8a-
dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzoxole
(4aS-trans)-4,4a,5,6,7,8,8a,9-
octahydro-3,8a-dimethyl-5-methylene naphtho(2,3-b)furan
(4aS,8aR)-3,8a-
dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzofuran
PubMed:
Differentiation of essential oils in Atractylodes lancea and Atractylodes koreana by gas chromatography with mass spectrometry.
PubMed:
Antiviral activities of atractylon from Atractylodis Rhizoma.
PubMed:
Quantitative and fingerprinting analysis of Atractylodes rhizome based on gas chromatography with flame ionization detection combined with chemometrics.
PubMed:
Anti-inflammatory and Antinociceptive Constituents of Atractylodes japonica Koidzumi.
PubMed:
Traditional herbal medicine for the control of tropical diseases.
PubMed:
Chemical composition and major odor-active compounds of essential oil from PINELLIA TUBER (dried rhizome of Pinellia ternata) as crude drug.
PubMed:
[Verification of processing theory of "reducing ketone and dryness, and increasing ester and effect" for bran-fried atractylodes].
PubMed:
[UFLC/Q-TOF-MS based analysis on material base of atractylodis macrocephalae rhizoma stir-fried with wheat bran].
PubMed:
[Screening and identification of an endophytic fungus from Atractylodes lancea which utilizes volatile oil selectively].
PubMed:
[Study on processing technology and processing principles of atractrylodis macrocephalae rhizoma].
PubMed:
Anti-Oxidative Abilities of Essential Oils from Atractylodes ovata Rhizome.
PubMed:
Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis.
PubMed:
Gastroprotective activity of atractylenolide III from Atractylodes ovata on ethanol-induced gastric ulcer in vitro and in vivo.
PubMed:
Quantitative determination of atractylon in Atractylodis Rhizoma and Atractylodis Lanceae Rhizoma by 1H-NMR spectroscopy.
PubMed:
Intestinal permeability of sesquiterpenes in the caco-2 cell monolayer model.
PubMed:
Identification of volatile compounds of Atractylode lancea rhizoma using supercritical fluid extraction and GC-MS.
PubMed:
[Simultaneous determination of atractylenolide III, atractylenolide I and atractylon in Artactylodis macrocephala using microbore liquid chromatography].
PubMed:
[Studies on volatile oil from Atractylodes macrocephala with different distill methods].
PubMed:
[Fingerprint of volatile oil of Atractylodes lancea by GC-MS].
PubMed:
Toxicity of atractylon and atractylenolide III Identified in Atractylodes ovata rhizome to Dermatophagoides farinae and Dermatophagoides pteronyssinus.
PubMed:
Analysis of the sesquiterpenoids in processed Atractylodis Rhizoma.
PubMed:
Preparative isolation and purification of atractylon and atractylenolide III from the Chinese medicinal plant atractylodes macrocephala by high-speed counter-current chromatography.
PubMed:
Composition of the essential oil of rootstock from Cimicifuga simplex.
PubMed:
Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (+/-)-biatractylolide and (+/-)-biepiasterolide.
PubMed:
Cytotoxic activity of sesquiterpenoids from Atractylodes ovata on leukemia cell lines.
PubMed:
5-Lipoxygenase and cyclooxygenase-1 inhibitory active compounds from Atractylodes lancea.
PubMed:
Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants.
PubMed:
A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.
PubMed:
[Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes].
PubMed:
Restriction fragment length polymorphisms of rDNA and variation of essential oil composition in Atractylodes plants.
PubMed:
Specific inhibition of Na+,K(+)-ATPase activity by atractylon, a major component of byaku-jutsu, by interaction with enzyme in the E2 state.
PubMed:
Inhibitory effect of atractylon on tert-butyl hydroperoxide induced DNA damage and hepatic toxicity in rat hepatocytes.
PubMed:
Atractylodis Rhizoma extract and its component, atractylon, inhibit tumor promotion in mouse skin two-stage carcinogenesis.
PubMed:
[Imaging analysis of antiulcer action and the active constituent of Atractylodis rhizoma].
PubMed:
Clonal Propagation of Atractylodes japonica and A. ovata by Tip Tissue Culture and the Atractylon Content of Clonally Propagated Plants.
PubMed:
[Exploration on baking conditions for Atractylodes macrocephala Kloidz in qiweibaizhusan bags].
PubMed:
Mechanism of antihepatotoxic activity of atractylon, I: Effect on free radical generation and lipid peroxidation.
PubMed:
Antihepatotoxic principles of Atractylodes rhizomes.
PubMed:
STUDIES ON THE CONSTITUENTS OF ATRACTYLODES. IX. STRUCTURE AND AUTOXIDATION OF ATRACTYLON.
PubMed:
Structure and autoxidation of atractylon.