magnoshinin
naphthalene, 1,2-dihydro-5,7,8-trimethoxy-2,3-dimethyl-1-(2,4,5-trimethoxyphenyl)-, trans-(+-)-
Identification
| Name | magnoshinin |
| IUPAC | (1R,2S)-5,7,8-trimethoxy-2,3-dimethyl-1-(2,4,5-trimethoxyphenyl)-1,2-dihydronaphthalene |
| CAS Number | 86702-02-5 |
| FDA UNII | Search |
| Molecular Formula | C24 H30 O6 |
| Molecular Weight | 414.49830000 |
| Nikkaji Number | J473.395I |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 514.40 °C. @ 760.00 mm Hg (est) |
| Flash Point | 396.00 °F. TCC ( 202.30 °C. ) (est) |
| logP (o/w) | 5.090 (est) |
| Soluble in | water, 0.07742 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for magnoshinin usage levels up to | not for fragrance use. |
| Recommendation for magnoshinin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
trans-(±)-1,2-
dihydro-5,7,8-trimethoxy-2,3-dimethyl-1-(2,4,5-trimethoxyphenyl) naphthalene
naphthalene, 1,2-dihydro-5,7,8-trimethoxy-2,3-dimethyl-1-(2,4,5-trimethoxyphenyl)-, trans-(+-)-
(1R,2S)-5,7,8-
trimethoxy-2,3-dimethyl-1-(2,4,5-trimethoxyphenyl)-1,2-dihydronaphthalene
PubMed:
Inhibitory effects of anti-rheumatic drugs containing magnosalin, a compound from 'Shin-i' (Flos magnoliae), on the proliferation of synovial cells in rheumatoid arthritis models.
PubMed:
Inhibitory effect of magnosalin derived from Flos magnoliae on tube formation of rat vascular endothelial cells during the angiogenic process.
PubMed:
Inhibitory effects of magnoshinin and magnosalin, compounds from "Shin-i" (Flos magnoliae), on the competence and progression phases in proliferation of subcultured rat aortic endothelial cells.
PubMed:
Selective inhibition by magnosalin and magnoshinin, compounds from "Shin-i" (Flos magnoliae), of adjuvant-induced angiogenesis and granuloma formation in the mouse pouch.
PubMed:
Selective inhibition by magnosalin and magnoshinin, compounds from 'shin-i' (Flos magnoliae), of adjuvant-induced angiogenesis and granuloma formation in the mouse pouch.
PubMed:
Anti-Inflammatory Effect of Neolignans Newly Isolated from the Crude Drug "Shin-i" (Flos Magnoliae).