scopadulciol

Export Excel

6-benzoyl-12-methyl-13-oxo-9(12)-9(12)-dihomo-18-podocarpanol

CAS: 136565-26-9 C27 H36 O4 MW: 424.58072000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namescopadulciol
IUPAC(1R,2R,6R,7S,8S,10R,13R)-6-(hydroxymethyl)-2,6,13-trimethyl-12-oxotetracyclo[11.2.1.01,10.02,7]hexadec-8-yl benzoate
CAS Number136565-26-9
FDA UNIISearch
Molecular FormulaC27 H36 O4
Molecular Weight424.58072000

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 0.06813 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for scopadulciol usage levels up tonot for fragrance use.
Recommendation for scopadulciol flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

6- benzoyl-12-methyl-13-oxo-9(12)-9(12)-dihomo-18-podocarpanol (1R,2R,6R,7S,8S,10R,13R)-6-( hydroxymethyl)-2,6,13-trimethyl-12-oxotetracyclo[11.2.1.01,10.02,7]hexadec-8-yl benzoate PubMed: Scopadulciol, Isolated from Scoparia dulcis, Induces β-Catenin Degradation and Overcomes Tumor Necrosis Factor-Related Apoptosis Ligand Resistance in AGS Human Gastric Adenocarcinoma Cells. PubMed: Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis. PubMed: Investigation on traditional medicines of Guarany Indio and studies on diterpenes from Scoparia dulcis. PubMed: [Studies on evaluation of natural products for antiviral effects and their applications]. PubMed: The role of a HSV thymidine kinase stimulating substance, scopadulciol, in improving the efficacy of cancer gene therapy. PubMed: Evaluation of scopadulciol-related molecules for their stimulatory effect on the cytotoxicity of acyclovir and ganciclovir against Herpes simplex virus type 1 thymidine kinase gene-transfected HeLa cells. PubMed: Cytotoxic diterpenes from Scoparia dulcis. PubMed: Scopadulciol, an inhibitor of gastric H+, K(+)-ATPase from Scoparia dulcis, and its structure-activity relationships.