thiocyanic acid

hydrogen rhodanide

CAS: 463-56-9 C N S MW: 58.08300000

Identification

Namethiocyanic acid
IUPACthiocyanic acid
CAS Number463-56-9
FDA UNIIA5KWW7N91V
Molecular FormulaC N S
Molecular Weight58.08300000
MDL NumberMFCD00011428
Nikkaji NumberJ402B

Regulatory

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 146.00 to 147.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure 4.733000 mmHg @ 25.00 °C. (est)
Flash Point 108.00 °F. TCC ( 42.10 °C. ) (est)
logP (o/w) 0.429 (est)
Soluble in water, 4.361e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for thiocyanic acid usage levels up tonot for fragrance use.
Recommendation for thiocyanic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

mushroom PMC

Synonyms

amthio hydrogen rhodanide hydrogen thiocyanate weedazol tl PubMed: New data on photochemistry of the interstellar molecule: HNCS. Identification of the SHCN complex. PubMed: Avidity of IgG antibodies against meningococcal serogroup a polysaccharide and correlations with bactericidal activity in sera from meningitis patients and controls from Ethiopia. PubMed: Development of ultrasound-assisted emulsification microextraction for determination of thiocynate ion in human urine and saliva samples. PubMed: Assessment of IgG avidity against pertussis toxin and filamentous hemagglutinin via an adapted enzyme-linked immunosorbent assay (ELISA) using ammonium thiocyanate. PubMed: On-line detection of root-induced volatiles in Brassica nigra plants infested with Delia radicum L. root fly larvae. PubMed: Ion association in aqueous solutions probed through vibrational energy transfers among cation, anion, and water molecules. PubMed: Standardisation of metalloimmunoassay protocols for assessment of silver nanoparticle antibody conjugates. PubMed: Synthesis and bioactivity of pyrazole acyl thiourea derivatives. PubMed: Phytotoxicity of thiocyanate to rice seedlings. PubMed: Microscale chemistry-based design of eco-friendly, reagent-saving and efficient pharmaceutical analysis: a miniaturized Volhard's titration for the assay of sodium chloride. PubMed: Multicomponent reactions of ammonium thiocyanate, acyl chlorides, alkyl bromides, and enaminones: a facile one-pot synthesis of thiophenes. PubMed: Long-term conservation of HCV RNA at 4 degrees C using a new RNA stabilizing solution. PubMed: Synthesis of functionalized 1,2,4-triazole-3-thiones from ammonium isothiocyanate, acid chlorides, and arylhydrazines. PubMed: Extraction of high-quality epidermal RNA after ammonium thiocyanate-induced dermo-epidermal separation of 4 mm human skin biopsies. PubMed: A partial exploration of the potential energy surfaces of SCN and HSCN: implications for the enzyme-mediated detoxification of cyanide. PubMed: [Fluorescence spectra study of a new toxic protein from Malania oleifera]. PubMed: Isolation of the key intermediates in the catalyst-free conversion of oxiranes to thiiranes in water at ambient temperature. PubMed: A one-pot synthesis of functionalized thiazoles from acid chlorides, secondary amines, ethyl bromopyruvate, and ammonium thiocyanate. PubMed: Comparison of antioxidant and free radical scavenging activities of the essential oils from flowers and fruits of Otostegia persica Boiss. PubMed: Vibrational spectroscopic study of ionic association in poly(ethylene oxide)-NH4SCN polymer electrolytes. PubMed: Study of velocity and shear stress distributions in the impeller passages and the volute of a bio-centrifugal ventricular assist device. PubMed: Trace level determination of molybdenum in environmental and biological samples using surfactant-mediated liquid-liquid extraction. PubMed: Study of the interactions of sodium thiocyanate, potassium thiocyanate and ammonium thiocyanate in water+N,N-dimethylformamide mixtures by Raman spectroscopy. PubMed: Ultrasound-assisted thiocyanation of aromatic and heteroaromatic compounds using ammonium thiocyanate and DDQ. PubMed: Avidity of the immunoglobulin G response to a Neisseria meningitidis group C polysaccharide conjugate vaccine as measured by inhibition and chaotropic enzyme-linked immunosorbent assays. PubMed: Rapid, high-quality and epidermal-specific isolation of RNA from human skin. PubMed: Spectrophotometric determination of trazodone, amineptine and amitriptyline hydrochlorides through ion-pair formation with molybdenum and thiocyanate. PubMed: A novel one-pot, four component synthesis of some densely functionalized pyrroles. PubMed: Electrothermal atomic absorption spectrometric-determination of cobalt in human serum and urine. PubMed: [Study of molybdenum (V) thiocyanate complexes in the acidic aqueous solution]. PubMed: [Simultaneous determination of ammonium thiocyanate and its isomeride by dual wavelength multiplication subtractive spectrophotometry]. PubMed: Taming of a poison: biosynthesis of the NiFe-hydrogenase cyanide ligands. PubMed: On the in vitro antioxidative properties of melatonin. PubMed: In vitro antioxidant properties of dantrolene sodium. PubMed: Use of diffuse reflectance spectrometry in spot test reactions for quantitative determination of cations in water. PubMed: Identification of amino acid residues in CD81 critical for interaction with hepatitis C virus envelope glycoprotein E2. PubMed: Antioxidant properties of a North American ginseng extract. PubMed: Comparison of physical chemical properties of llama VHH antibody fragments and mouse monoclonal antibodies. PubMed: Spectrophotometric study of diclofenac-Fe(III) complex. PubMed: A method for preparation of amino acid thiohydantoins from free amino acids activated by acetyl chloride for development of protein C-terminal sequencing. PubMed: Evaluation of the allergic/irritant potential of air pollutants: detection of proteins modified by volatile organic compounds from oilseed rape (Brassica napus ssp. oleifera) using electrospray ionization-mass spectrometry. PubMed: The role of pH in modified ELISA procedures used for the estimation of functional antibody affinity. PubMed: Formation of proline thiohydantoin with ammonium thiocyanate: progress towards a viable C-terminal amino-acid-sequencing procedure. PubMed: Ammonium thiocyanate for detaching antibodies from histological specimens. PubMed: Serum HCG beta-core fragment is masked by associated macromolecules. PubMed: [Status of immunological reactivity in workers engaged in the production of thiourea, ammonium rhodanate and cobalt and manganese salts]. PubMed: Investigation of penbutolol-iron (III) complex and its spectrophotometric determination in tablets. PubMed: [Characteristics of toxicokinetics of ammonium thiocyanate]. PubMed: [Effect of ammonium thiocyanate and thiourea on the immune system]. PubMed: [Validation of the tentative safety levels of thiourea and ammonium thiocyanate in the air]. PubMed: [Method of determining ammonium thiocyanate]. PubMed: [Data providing a basis for the maximum allowable concentration of ammonium thiocyanate in workplace air]. PubMed: Swelling and contraction of the mitochondrial matrix. II. Quantitative application of the light scattering technique to solute transport across the inner membrane. PubMed: Determination of isocyano groups on polymer supports by bromination. PubMed: SCN-and HSCN transport through lipid bilayer membranes. A model for SCN- inhibition of gastric acid secretion. PubMed: Biochemical identification of pharmacologically and functionally distinct GABA receptors in rat brain. PubMed: Dermatitis from ivy (Hedera canariensis variegata). PubMed: Synthesis of phospholipids in microstructures, prepared by the interaction of ammonium thiocyanate, minerals, calcium acetate, potassium dihydrogen phosphate, and formaldehyde. PubMed: Determination of sulphur by electrolytic hydrogenation. PubMed: Use of thiocyanic acid to form 2-thiohydantoins at the carboxyl terminus of proteins. PubMed: [Investigations of the reaction kinetics in the formation of 7-chloro-2N-nitrosomethylamino-5-phenyl-3H-1,4-benzodiazepine-4-oxide (author's transl)]. PubMed: [Thiocyanic acid derivatives of activated methylene compounds. 14. Studies on acylenamines]. PubMed: Solvent extraction behaviour of thiocyanic acid. PubMed: Studies on digitalis glycosides. XXIV. Ring opening reaction of 14,15-epoxide with thiocyanic acid, and preparation of 3-beta-hydroxy-14-beta,15-beta-epithio-5-beta-card-20(22)-enolide. PubMed: Chromatography on ion exchange papers. XIX. Ion exchange of metal ions in thiocyanic acid. PubMed: [Schiff bases of 4-rhodananiline and their fungistatic properties (part 1). Part 2. On organic thiocyanic acid derivatives]. PubMed: [Thiocyanic acid in the salivary balance of persons with dentures]. PubMed: [Effect of a fixed thiocyanic acid (orthromin) on Jensen sarcoma in white rat]. PubMed: A synthesis of amine salts of thiocyanic acid. PubMed: [Not Available].