eremanthin
vanillosmin
Identification
| Name | eremanthin |
| IUPAC | (3aS,6aR,9aR,9bS)-6-methyl-3,9-dimethylidene-4,6a,7,8,9a,9b-hexahydro-3aH-azuleno[5,4-d]furan-2-one |
| CAS Number | 37936-58-6 |
| FDA UNII | Search |
| Molecular Formula | C15 H18 O2 |
| Molecular Weight | 230.30686000 |
| Nikkaji Number | J17.120D |
Regulatory
Physical Properties
| Assay | 80.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 288.00 to 290.00 °C. @ 760.00 mm Hg |
| Flash Point | 326.00 °F. TCC ( 163.33 °C. ) |
| logP (o/w) | 1.530 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for eremanthin usage levels up to | not for fragrance use. |
| Recommendation for eremanthin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
eremanthine
(3aS,6aR,9aR,9bS)-6-
methyl-3,9-dimethylidene-4,6a,7,8,9a,9b-hexahydro-3aH-azuleno[5,4-d]furan-2-one
(3aS-(3aalpha, 6aalpha,9aalpha,9bbeta))- 3a,4,6a,7,8,9,9a,9b-
octahydro-6-methyl-3,9-bis(methylene) azuleno(4,5-b)furan-2(3H)-one
vanillosmin
PubMed:
Antimicrobial activity of sesquiterpene lactones isolated from traditional medicinal plant, Costus speciosus (Koen ex.Retz.) Sm.
PubMed:
Antioxidant activity of costunolide and eremanthin isolated from Costus speciosus (Koen ex. Retz) Sm.
PubMed:
Antidiabetic and antilipidemic effect of eremanthin from Costus speciosus (Koen.)Sm., in STZ-induced diabetic rats.
PubMed:
Guaianolides as immunomodulators. Synthesis and biological activities of dehydrocostus lactone, mokko lactone, eremanthin, and their derivatives.
PubMed:
Genotoxicity of the natural cercaricides "sucupira" oil and eremanthine in mammalian cells in vitro and in vivo.