ginkgetin

ginkgetin 7''-O-b-D-glucopyranoside

CAS: 481-46-9 C32 H22 O10 MW: 566.51934000

Identification

Nameginkgetin
CAS Number481-46-9
FDA UNIIHY5EZW8269
Molecular FormulaC32 H22 O10
Molecular Weight566.51934000
Nikkaji NumberJ92.485G

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 863.70 °C. @ 760.00 mm Hg (est)
Flash Point 549.00 °F. TCC ( 287.20 °C. ) (est)
logP (o/w) 4.450 (est)
Soluble in water, 0.002419 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for ginkgetin usage levels up tonot for fragrance use.
Recommendation for ginkgetin flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

ginkgo biloba

Synonyms

4H-1- benzopyran-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)- 3''',8- biflavone, 4',5,5'',7-tetrahydroxy-4''',7''-dimethoxy- 5,7- dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 5,7- dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one 5,7- dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one 7,4'- dimethyl amentoflavone 7,4'- dimethylamentoflavone ginkgetin 7''-O-b-D-glucopyranoside PubMed: Neuroprotective biflavonoids of Chamaecyparis obtusa leaves against glutamate-induced oxidative stress in HT22 hippocampal cells. PubMed: Ginkgetin induces apoptosis via activation of caspase and inhibition of survival genes in PC-3 prostate cancer cells. PubMed: Two new nonacosanetriols from Ginkgo biloba sarcotesta. PubMed: Biflavonoids from Caper (Capparis spinosa L.) fruits and their effects in inhibiting NF-kappa B activation. PubMed: Target-guided isolation and purification of antioxidants from Selaginella sinensis by offline coupling of DPPH-HPLC and HSCCC experiments. PubMed: A new dilactone from the seeds of Gaultheria yunnanensis. PubMed: [Structrue identification of biflavones and determination of Taxol from Taxus Madia]. PubMed: Inhibition of arachidonate release from rat peritoneal macrophage by biflavonoids. PubMed: Biochemical pharmacology of biflavonoids: implications for anti-inflammatory action. PubMed: Seco-terpenoids and other constituents from Elateriospermum tapos. PubMed: Anti-inflammatory activity of the synthetic C-C biflavonoids. PubMed: Anti-influenza virus activity of biflavonoids. PubMed: Effects of anti-inflammatory biflavonoid, ginkgetin, on chronic skin inflammation. PubMed: Biflavonoids inhibited phosphatase of regenerating liver-3 (PRL-3). PubMed: Osteoblast differentiation stimulating activity of biflavonoids from Cephalotaxus koreana. PubMed: Inhibition of cGMP-phosphodiesterase-5 by biflavones of Ginkgo biloba. PubMed: Comparative antiplasmodial, leishmanicidal and antitrypanosomal activities of several biflavonoids. PubMed: Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. PubMed: Biflavones from Chamaecyparis obtusa. PubMed: Biflavonoids from Brazilian pine Araucaria angustifolia as potentials protective agents against DNA damage and lipoperoxidation. PubMed: Biflavone glucosides from Ginkgo biloba yellow leaves. PubMed: Neuroprotective effects of naturally occurring biflavonoids. PubMed: Flavonoids from Metasequoia glyptostroboides. PubMed: [The effects of ginaton on cochlear microcirculation]. PubMed: Antifungal activity of biflavones from Taxus baccata and Ginkgo biloba. PubMed: Flavonoids differentially inhibit guinea pig epidermal cytosolic phospholipase A2. PubMed: Effects of Ginkgetin from Ginkgo biloba Leaves on cyclooxygenases and in vivo skin inflammation. PubMed: Biflavones of Ginkgo biloba stimulate lipolysis in 3T3-L1 adipocytes. PubMed: Effect of biflavones of Ginkgo biloba against UVB-induced cytotoxicity in vitro. PubMed: Effects of prenylated flavonoids and biflavonoids on lipopolysaccharide-induced nitric oxide production from the mouse macrophage cell line RAW 264.7. PubMed: Studies on the cytotoxic mechanisms of ginkgetin in a human ovarian adenocarcinoma cell line. PubMed: The effects of two new antagonists of secretory PLA2 on TNF, iNOS, and COX-2 expression in activated macrophages. PubMed: Inhibition of rat adjuvant-induced arthritis by ginkgetin, a biflavone from ginkgo biloba leaves. PubMed: Inhibition of cAMP-phosphodiesterase by biflavones of Ginkgo biloba in rat adipose tissue. PubMed: Effects of naturally-occurring flavonoids and biflavonoids on epidermal cyclooxygenase and lipoxygenase from guinea-pigs. PubMed: [HPLC determination of six flavonoid constituents in Ginkgo biloba leaves]. PubMed: Selective cytotoxicity of ginkgetin from Selaginella moellendorffii. PubMed: Effects of flavonoids of Ginkgo biloba on proliferation of human skin fibroblast. PubMed: Suppression of mouse lymphocyte proliferation in vitro by naturally-occurring biflavonoids. PubMed: Mechanism of action of the antiherpesvirus biflavone ginkgetin. PubMed: Effects of some compounds isolated fromCelaenodendron mexicanum standl (euphorbiaceae) on seeds and phytopathogenic fungi. PubMed: HPLC Separation and Quantitative Determination of Biflavones in Leaves from Ginkgo biloba.