kolavenic acid

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cleroda-3,13E-dien-15-oic acid

CAS: 25436-90-2 C20 H32 O2 MW: 304.47344000
All Ingredients Aromatic Ingredients CAS Numbers Found in Nature

Identification

Namekolavenic acid
CAS Number25436-90-2
FDA UNIISearch
Molecular FormulaC20 H32 O2
Molecular Weight304.47344000
Nikkaji NumberJ34.240H

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 416.08 °C. @ 760.00 mm Hg (est)
Flash Point 591.00 °F. TCC ( 310.80 °C. ) (est)
logP (o/w) 7.088 (est)
Soluble in water, 0.01576 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for kolavenic acid usage levels up tonot for fragrance use.
Recommendation for kolavenic acid flavor usage levels up tonot for flavor use.

No supplier data available

Potential Uses

None Found

Natural Occurrence

found in nature

Synonyms

cleroda-3,13E-dien-15-oic acid (1S-(1alpha(E),2beta,4abeta,8aalpha))-3- methyl-5-(1,2,3,4,4a,7,8,8a-octahydro-1,2,4a,5-tetramethyl-1-naphthalenyl)-2-pentenoic acid (E)-5-[(1S,2R,4aR,8aR)-1,2,4a,5- tetramethyl-2,3,4,7,8,8a-hexahydronaphthalen-1-yl]-3-methylpent-2-enoic acid PubMed: Clerodane diterpenes isolated from Polyalthia longifolia induce apoptosis in human leukemia HL-60 cells. PubMed: An unusual bisnor-clerodane diterpenoid from Polyalthia simiarum. PubMed: Antimicrobial activity of various parts of Polyalthia longifolia var. pendula: isolation of active principles from the leaves and the berries. PubMed: Evaluation of insecticidal activity of diterpenes and lignans from Aristolochia malmeana against Anticarsia gemmatalis. PubMed: (-)-kolavenic Acid. PubMed: Hypotensive activity and toxicology of constituents from root bark of Polyalthia longifolia var. pendula. PubMed: Antifungal clerodane diterpenes from Macaranga monandra (L) Muell. et Arg. (Euphorbiaceae). PubMed: New antimicrobial alkaloids from the roots of Polyalthia longifolia var. pendula. PubMed: Cytotoxic clerodane diterpenes from Polyalthia longifolia.