deoxynupharidine
4-(furan-3-yl)-1,7-dimethyloctahydro-2h-quinolizine
Identification
| Name | deoxynupharidine |
| CAS Number | 1143-54-0 |
| FDA UNII | Search |
| Molecular Formula | C15 H23 N O |
| Molecular Weight | 233.35451000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 308.34 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point | 285.00 °F. TCC ( 140.30 °C. ) (est) |
| logP (o/w) | 5.045 (est) |
| Soluble in | water, 40.54 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for deoxynupharidine usage levels up to | not for fragrance use. |
| Recommendation for deoxynupharidine flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
desoxynupharidine
4-(
furan-3-yl)-1,7-dimethyl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine
4-(
furan-3-yl)-1,7-dimethyloctahydro-2h-quinolizine
(1R-(1alpha,4beta,7beta,9aalpha))-4-(3-
furanyl) octahydro-1,7-dimethyl-2H-quinolizine
nupharidine, deoxy-
PubMed:
Vinylogous Mukaiyama-Michael Reactions of Dihydropyridinones.
PubMed:
Development of a flexible approach to Nuphar alkaloids via two enantiospecific piperidine-forming reactions.
PubMed:
Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
PubMed:
A concise asymmetric route to Nuphar alkaloids. A formal synthesis of (-)-deoxynupharidine.
PubMed:
Dimeric sesquiterpene thioalkaloids with potent immunosuppressive activity from the rhizome of Nuphar pumilum: structural requirements of nuphar alkaloids for immunosuppressive activity.
PubMed:
[Effect of deoxynupharidine on immune function in vitro].
PubMed:
Actions of desoxynupharidine hydrochloride in the central nervous system of cats (II).
PubMed:
Actions of desoxynupharidine hydrochloride in the central nervous system of experimental animals (I).
PubMed:
Preparation and in vitro antifungal activities of some quinolizidine derived hemiaminals and beta-tert-amino sulfides.
PubMed:
[Studies on 1-azabicyclo compounds. XXIII. Mercuric acetate oxidation of deoxynupharidine (author's transl)].
PubMed:
[Syntheses of deoxynupharidine derivatives].
PubMed:
Constituents of rhizoma Nupharis. XXV. Formation of dehydro-deoxynupharidine from nupharidine.
PubMed:
Constituents of Rhizoma Nupharis. XXI. Structure of dehydro-deoxynupharidine.
PubMed:
Dehydro-deoxynupharidine: a new alkaloid of Nuphar japonicum DC.
PubMed:
Constituents of rhizoma nupharis. 18. Synthesis of alkaloids from Nuphar japonicum DC. I. Synthesis of rac-deoxynupharidine.
PubMed:
[Constituents of rhizoma nupharis. XVII. The absolute configuration of deoxynupharidine. (1)].