Identification

Namevanillyl isobutyrate
IUPAC(4-formyl-2-methoxyphenyl) 2-methylpropanoate
CAS Number20665-85-4
EINECS243-956-6
FDA UNIIC55654RCNR
Molecular FormulaC12 H14 O4
Molecular Weight222.24038000
MDL NumberMFCD00169858
Nikkaji NumberJ120.486F

Regulatory

JECFA Food Flavoring891 vanillin isobutyrate
DG SANTE Food Flavourings09.811 vanillin isobutyrate
FEMA Number3754
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)20665-85-4 ; VANILLIN ISOBUTYRATE

Physical Properties

Appearance colorless to yellow clear liquid (est)
Assay 98.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.13200 to 1.14000 @ 25.00 °C., 1.13200 to 1.14200 @ 20.00 °C.
Pounds per Gallon - (est). 9.419 to 9.486
Pounds per Gallon - est. 9.430 to 9.514
Refractive Index 1.52000 to 1.52600 @ 20.00 °C.
Boiling Point 165.00 to 166.00 °C. @ 2.00 mm Hg
Acid Value 2.00 max. KOH/g
Vapor Pressure 0.001000 mmHg @ 25.00 °C. (est)
Flash Point > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w) 1.980 (est)
Soluble in alcohol

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength medium
Substantivity > 400 hour(s) at 100.00 %
Odor Description
at 100.00 %.
Vanilla, Sweet, Fruity
sweet balsam vanilla
Heavy, sweet, vanilla, nutmeg
sweet aromatic, floral; characteristic vanilla and cocoa
Sweet, vanilla, creamy with notes of white chocolate and caramel
Odor sample from Takasago International Corp
Taste Description
sweet vanilla powdery chocolate creamy buttery fruity cheesy
sweet aromatic, slightly vanilla, fruity
sweet aromatic vanilla fruity

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Oral/Parenteral Toxicitygavage-rat LD50 [sex: M,F] 4755 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for vanillyl isobutyrate usage levels up to2.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)55.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)0.04 (μg/capita/day)
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum-
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings-
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

Alfrebro LLC/ Archer Daniels Midland Company

Let's get reacquainted

Building great taste with aroma chemicals, extracts, and distillates

View All Website 513-539-7373 sforbis@alfrebro.com

Augustus Oils Ltd

The Premier Supplier

Augustus Oils Ltd, in harmony with nature - to present it at its best...

View All Website +44 (0)1420 590555 essentials@augustus-oils.ltd.uk

Beijing Lys Chemicals Co, LTD.

From Grams to Tons

Fine chemical high-tech company which contains R&D, production, and sales.

View All Website 86-10-68418738 jiayanyong@lyschem.com

Berje Inc.

Where the world comes to its senses

Where the world comes to its senses - Berjé is a global distributor of Essential Oils and Aromatic Chemicals.

View All Website 973-748-8980 tlauzurica@berjeinc.com

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Charkit Chemical Corporation

The Specialty Chemical Specialists

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Indukern, S.A. F&F Ingredients Division

Commitment to quality

Idukern F&F Ingredients is your partner for the fragrance and flavor ingredients.

View All Website +34 93 506 91 00 info@indukern.es

Jiangyin Healthway International Trade Co., Ltd

Independent Ingredients Supplier

We provide custom synthesis and contract manufacturing from milligrams to metric tonnes.

View All Website 86-510-86023169 info@healthwaychem.com

Lluch Essence S.L.

A family company dedicated to sales and distribution

Flexibility, availability, price and quality.

View All Website 34 93 379 38 49 web@lluche.com

M&U International LLC

Steady supply & demand

Meeting customers increasing demands at home as well as abroad.

View All Website 908-359-9000 sales@mu-intel.com

Moellhausen S.P.A.

THE CHEMISTRY OF EMOTIONS

Innovation and commitment in the name of excellence.

View All Website +39 039.685.6262

O'Laughlin Industries Inc.

Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics

Leading the Flavor and Fragrance Industry since 1980.

View All Website (973) 376-4600 olcorphk@hkstar.com

Penta International Corporation

Chemistry innovation

At Penta, our products and services help businesses do business better.

View All Website (973) 740-2300 lisaa@pentamfg.com

Prodasynth

PRODUCTEUR PAR ESSENCE

Chemical specialist in manufacturing, distributing and sourcing of tailor-made ingredients for the Flavour & Fragrance industry.

View All Website (33) 4 93 09 00 11 info@prodasynth.com

Sigma-Aldrich

Complete Supply Chain

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View All Website 800-244-1173 ff@sial.com

SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

Sunaux International

Buy With Confidence

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View All Website 0512-57995626 johnjft@sunaux.com

Synerzine, Inc.

Innovation. Customization. Aroma Ingredients.

Synerzine is a leading supplier of flavor and fragrance ingredients.

View All Website (404) 524-6744 info@synerzine.com

Taytonn ASCC Pte Ltd

Supplying Asia Pacific

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View All Website + 65 - 6861 8113 info@taytonnascc.com

TCI AMERICA

Moving Your Chemistry Forward

We continuously strive to advance our technology.

View All Website 1-800-423-8616 Sales-US@TCIchemicals.com;

The John D. Walsh Company, Inc

Suppliers Since 1942

Supplying the fragrance and flavor industry with high quality products.

View All Website 973-962-1400 info@johndwalsh.com

The Lermond Company

Your Sourcing Resource

The Lermond family has been sourcing raw materials for the flavor and fragrance industry for nearly 7 decades.

View All Website 201-896-3300 info@lermond.com

Tianjin Danjun International Trade Co., LTD.

Quality Products

We know the Chinese chemical market well.

View All Website +86-15822601686 songshasha@danjunchem.com

Qingdao Free Trade Zone United International Co Ltd

Quality Products

A partner in your supply chain solution.

View All Website +86-532-83893699 info@unitedint.com

Ernesto Ventós S.A.

Leaders in essence

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Vigon International

Passion for Simplicity

Manufacturer and supplier of high quality flavor and fragrance ingredients.

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WholeChem, LLC

Connecting Innovators To the Building Blocks Of the Universe

Custom manufacturer and distributor of specialty ingredients. We make global local.

View All Website +1 (262) 995.8668 info@wholechem.com

Potential Uses

FR balsam FR butterscotch FL caramel FR chocolate FR cream FL soda cream soda FR toffee FR vanilla

Natural Occurrence

not found in nature

Synonyms

iso butavan (Givaudan) iso butyl lignate iso butyric acid ester with vanillin 4- formyl-2-(methyloxy)phenyl 2-methylpropanoate 4- formyl-2-methoxyphenyl 2-methylpropanoate 4- formyl-2-methoxyphenyl isobutyrate (4- formyl-2-methoxyphenyl) 2-methylpropanoate 4- hydroxy-3-methoxybenzaldehyde 2-methyl propionate 4- hydroxy-3-methoxybenzaldehyde isobutyrate 4- hydroxy-m-anisaldehyde 2-methylpropionate 4- hydroxy-m-anisaldehyde isobutyrate 4- hydroxy-meta-anisaldehyde 2-methyl propionate 4- hydroxy-meta-anisaldehyde isobutyrate 3- methoxy-4-isobutyryl benzaldehyde 2- methyl propanoic acid 4-formyl-2-methoxyphenyl ester propanoic acid, 2-methyl-, 4-formyl-2-methoxyphenyl ester vanillin iso butyrate vanillin isobutyrate vanillin isobutyrate natural vanillin-iso-butyrate vanillinisobutyrate PubMed: Experience influences elemental and configural perception of certain binary odour mixtures in newborn rabbits. PubMed: A comprehensive evaluation of the toxicology of cigarette ingredients: aromatic carbonyl compounds. PubMed: Fate of key odorants in Sauternes wines through aging. PubMed: Similarities in the aroma chemistry of Gewürztraminer variety wines and lychee (Litchi chinesis sonn.) fruit.