lidocaine hydrochloride
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, hydrochloride (1:1)
Identification
| Name | lidocaine hydrochloride |
| IUPAC | 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride |
| CAS Number | 73-78-9 |
| EINECS | 200-803-8 |
| FDA UNII | EC2CNF7XFP |
| Molecular Formula | C14 H23 Cl N2 O |
| Molecular Weight | 270.80251000 |
| MDL Number | MFCD00150329 |
| Beilstein | 3917968 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 350.80 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000043 mmHg @ 25.00 °C. (est) |
| Flash Point | 331.00 °F. TCC ( 166.00 °C. ) (est) |
| logP (o/w) | 2.359 (est) |
| Soluble in | water, 1473 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | intravenous-child TDLo 60 mg/kg/1H |
| Dermal Toxicity | subcutaneous-mouse LD50 163 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements', 'BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD\nVASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION', 'LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION\nBEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for lidocaine hydrochloride usage levels up to | not for fragrance use. |
| Recommendation for lidocaine hydrochloride flavor usage levels up to | not for flavor use. |
American International Chemical, Inc.
Consistent sources
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Penta International Corporation
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Potential Uses
Natural Occurrence
Synonyms
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, chloride, hydrogen salt (1:1)
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, hydrochloride (1:1)
acetamide, 2-(diethylamino)-N-(2,6-dimethylphenyl)-, monohydrochloride
2',6'-
acetoxylidide, 2-(diethylamino)-, hydrochloride
2',6'-
acetoxylidide, 2-(diethylamino)-, monohydrochloride
anestacon hydrochloride
a-
diethylamino-2,6-acetoxylidine hydrochloride
2-
diethylamino-2',6'-acetoxylidide hydrochloride
diethylamino)-2',6'-acetoxylidide monohydrochloride
2-(
diethylamino)-n-(2,6-dimethylphenyl)-acetamide hydrochloride
2-(
diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride
2-(
diethylamino)-N-(2,6-dimethylphenyl)acetamide monohydrochloride
2-(
diethylamino)-N-(2,6-dimethylphenyl)acetamide, hydrochloride (1:1)
2-(
diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride
2-(
diethylamino)-N-(2,6-dimethylphenyl)acetamidhydrochlorid
N-(
diethylaminoacetyl)-2,6-dimethylaniline hydrochloride
N-(2,6-
dimethylphenyl)-N(2),N(2)-diethylglycinamide hydrochloride
N-(2,6-
dimethylphenyl)-N2,N2-diethylglycinamide hydrochloride
duncaine hydrochloride
gravocain hydrochloride
isicaine hydrochloride
leostesin hydrochloride
lidocain hydrochloride
lidocaine HCl
lidothesin hydrochloride
lignocaine hydrochloride
linocaine hydrochloride
metaclopramide hydrochloride
rucaina hydrochloride
xilina hydrochloride
xycaine hydrochloride
xylestesin hydrochloride
xylocaine hydrochloride
xylocaine MPF
xylocitin hydrochloride
xylotox hydrochloride
PubMed:
Study on patients who underwent suspected diagnosis of allergy to amide-type local anesthetic agents by the leukocyte migration test.
PubMed:
Efficacy of articaine formulations: quantitative reviews.
PubMed:
Evaluation of middle and distal esophageal diverticuli with transnasal esophagoscopy.
PubMed:
Bi-hemispheric contribution to functional motor recovery of the affected forelimb following focal ischemic brain injury in rats.
PubMed:
Local and regional anesthesia in ruminants and swine.
PubMed:
Factors affecting the voluntary intake of food by sheep. 5. The inhibitory effect of hypertonicity in the rumen.
PubMed:
Techniques of local analgesia in ruminants and swine.
PubMed:
Stability of sterile aqueous lidocaine hydrochloride and epinephrine injections submitted by U.S. hospitals.
PubMed:
Evaluation of preparations of patent blue (Alphazurine 2G) dye for parenteral use.