polymixin B sulfate
aerosporin
Identification
| Name | polymixin B sulfate |
| CAS Number | 1405-20-5 |
| EINECS | 215-774-7 |
| FDA UNII | 19371312D4 |
| Molecular Formula | C48 H84 N16 O17 S |
| Molecular Weight | 1189.36088000 |
| MDL Number | MFCD00131991 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 1611.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 1703.00 °F. TCC ( 928.10 °C. ) (est) |
| logP (o/w) | -6.361 (est) |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | intravenous-dog LDLo 8 mg/kg |
| Dermal Toxicity | subcutaneous-guinea pig LD50 58 mg/kg |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | pharmaceuticals / chemical synthisis |
| Recommendation for polymixin B sulfate usage levels up to | not for fragrance use. |
| Recommendation for polymixin B sulfate flavor usage levels up to | not for flavor use. |
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Penta International Corporation
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Potential Uses
Natural Occurrence
Synonyms
aerosporin
chloromyxin
neobacimyx
neosporin plus
pediotic suspension
neo-
polycin
polymixin-b-sulfate
polymyxin B sulfate
polymyxin B sulphate
polymyxin B, sulfate
polymyxin B, sulfate (salt)
polytrim
PubMed:
Identification and characterization of chlorpyrifos-methyl and 3,5,6-trichloro-2-pyridinol degrading Burkholderia sp. strain KR100.
PubMed:
Simultaneous identification and quantitative determination of neomycin sulfate, polymixin B sulfate, zinc bacytracin and methyl and propyl hydroxybenzoates in ophthalmic ointment by TLC.
PubMed:
Anaphylaxis caused by polymixin B sulfate and zinc bacitracin ointment.
PubMed:
Intra-amygdala kinase inhibitors disrupt retention of a learned avoidance response in rats.
PubMed:
Effect of antibiotics on motion characteristics of cooled stallion spermatozoa.
PubMed:
Bacterial activation of human natural killer cells: role of cell surface lipopolysaccharide.
PubMed:
Histamine H2-receptor mediated activation of neonatal rat brain ornithine decarboxylase in vivo.
PubMed:
Use of a semen extender containing antibiotic to improve the fertility of a stallion with seminal vesiculitis due to Pseudomonas aeruginosa.
PubMed:
Ca2+/diacylglycerol-activated, phospholipid-dependent protein kinase in the Hermissenda CNS.
PubMed:
Effects of bacterial lipopolysaccharide on protein synthesis in murine peritoneal macrophages: relationship to activation for macrophage tumoricidal function.
PubMed:
Interaction of wheat germ ca-dependent protein kinases with calmodulin antagonists and polyamines.
PubMed:
Calcium/phosphatidylserine/diacylglycerol-dependent protein phosphorylation in the Aplysia nervous system.
PubMed:
Prophylactic antibiotics in cataract surgery.
PubMed:
Increased selectivity of Mitis-Salivarius agar containing polymyxin.
PubMed:
Electron microscope observations on the effects of polymixin B sulfate on cell walls of Chlamydia psittaci.