16-kaurene
kaur-16-ene
Identification
| Name | 16-kaurene |
| CAS Number | 562-28-7 |
| FDA UNII | Search |
| Molecular Formula | C20 H32 |
| Molecular Weight | 272.47504000 |
Regulatory
Physical Properties
| Assay | 92.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 346.00 to 348.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.000111 mmHg @ 25.00 °C. (est) |
| Flash Point | 338.00 °F. TCC ( 170.00 °C. ) |
| logP (o/w) | 8.469 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | information only not used for fragrances or flavors |
| Recommendation for 16-kaurene usage levels up to | not for fragrance use. |
| Recommendation for 16-kaurene flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
kaur-16-ene
(-)-
kaur-16-ene
PubMed:
Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum.
PubMed:
Microbial transformation of the diterpene 7-epi-foliol by Fusarium fujikuroi.
PubMed:
Diterpenes and phenolic compounds from Sideritis pullulans.
PubMed:
Two new natural products from Croton kongensis Gagnep.
PubMed:
Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations.
PubMed:
[Chemical constituents from seeds of Vigna umbellata].
PubMed:
Headspace, solid-phase micro-extraction, gas chromatographic-mass spectrometric analysis of terpenoids in the latex of Euphorbia species.
PubMed:
Cytotoxic and apoptosis-inducing activities of steviol and isosteviol derivatives against human cancer cell lines.
PubMed:
Biotransformation of ent-kaur-16-ene and ent-trachylobane 7β-acetoxy derivatives by the fungus Gibberella fujikuroi (Fusarium fujikuroi).
PubMed:
Chemical composition and antitermitic activity against Coptotermes formosanus Shiraki of Cryptomeria japonica leaf essential oil.
PubMed:
Determination and potential importance of diterpene (kaur-16-ene) emitted from dominant coniferous trees in Japan.
PubMed:
Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MS.
PubMed:
Analgesic and anti-inflammatory activities of 18-acetoxy-ent-kaur-16-ene from Annona squamosa L. bark.
PubMed:
15α,20β-Dihydr-oxy-6β-meth-oxy-6,7-seco-6,20-ep-oxy-1,7-olide-ent-kaur-16-ene.
PubMed:
6β,15β-Diacet-oxy-1β,7β,13α-trihydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene.
PubMed:
1α,6β,7β,11α,15β-Penta-hydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene.
PubMed:
6β-Acet-oxy-1α,7β,11β,15β-tetra-hydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene.
PubMed:
Cholinesterase and BACE1 inhibitory diterpenoids from Aralia cordata.
PubMed:
Chemical constituents of Isodon nervosus and their cytotoxicity.
PubMed:
Comparison of chemical compositions and antimicrobial activities of essential oils from three conifer trees; Pinus densiflora, Cryptomeria japonica, and Chamaecyparis obtusa.
PubMed:
An ent-kaurane diterpenoid from Isodon japonica var. glaucocalyx.
PubMed:
1α,6β,7β,14β,15β-Penta-hydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene.
PubMed:
Antiacetylcholinesterase and antioxidant ent-Kaurene diterpenoid, melissoidesin from Isodon wightii (Bentham) H. Hara.
PubMed:
Diterpenoids from the roots of Suregada glomerulata.
PubMed:
Isolation and biological activity of new and known isolation and biological activity of new and known diterpenoids from Sideritis stricta Boiss. & Heldr.
PubMed:
ent-Kaurenoids from the roots of Cacalia pilgeriana.
PubMed:
The microbiological transformation of 7alpha-hydroxy-ent-kaur-16-ene derivatives by Gibberella fujikuroi.
PubMed:
Antibacterial diterpenoids from Sagittaria pygmaea.
PubMed:
Functional characterization of the rice kaurene synthase-like gene family.
PubMed:
Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora.
PubMed:
Major volatile constituents of Annona squamosa L. bark.
PubMed:
Sylviside, a diterpene glucoside derivative from Gnaphalium sylvaticum.
PubMed:
Mono and diterpene production in Escherichia coli.
PubMed:
The microbiological transformation of two 15beta-hydroxy-ent-kaurene diterpenes by Gibberella fujikuroi.
PubMed:
Composition and antimicrobial activity of the essential oils from invasive species of the Azores, Hedychium gardnerianum and Pittosporum undulatum.
PubMed:
On the ent-kaurene diterpenes from Sideritis athoa.
PubMed:
Microbial transformation of 18-hydroxy-9,13-epi-ent-pimara-7,15-diene by Gibberella fujikuroi.
PubMed:
Biotransformation of the diterpenes epicandicandiol and candicandiol by Mucor plumbeus.
PubMed:
ent-Kaurene and squalene synthesis in Fusarium fujikuroi cell-free extracts.
PubMed:
The steam volatile oil of Wollemia nobilis and its comparison with other members of the Araucariaceae (Agathis and Araucaria).
PubMed:
A new diterpene glycoside from Rabdosia rubescens.
PubMed:
Diterpenoids from isodon eriocalyx
PubMed:
Megathyrin B: a cytotoxic diterpene from Isodon megathyrsus.
PubMed:
Isolation of two cytotoxic diterpenes from the fern Pteris multifida.
PubMed:
Antimicrobial activity of natural and semisynthetic diterpenoids from Sideritis spp.
PubMed:
Biosynthesis of rice phytoalexins: identification of putative diterpene hydrocarbon precursors.
PubMed:
Structure Elucidation of Inflexarabdonins G and H: Two New Diterpenoids from Rabdosia inflexa.
PubMed:
Isolation of gibberellin precursors from heavily pigmented tissues.
PubMed:
ent-Kaurene Biosynthesis in Cell-Free Extracts of Excised Parts of Tall and Dwarf Pea Seedlings.
PubMed:
Relationship between Chloroplast Development and ent-Kaurene Biosynthesis in Peas.
PubMed:
Diterpene biosynthesis in maize seedlings in response to fungal infection.
PubMed:
Studies on the Specificity and Site of Action of alpha-Cyclopropyl-alpha-[p-methoxyphenyl]-5-pyrimidine Methyl Alcohol (Ancymidol), a Plant Growth Regulator.
PubMed:
Properties of the System for the Mixed Function Oxidation of Kaurene and Kaurene Derivatives in Microsomes of the Immature Seed of Marah macrocarpus: Electron Transfer Components.
PubMed:
Properties of the System for the Mixed Function Oxidation of Kaurene and Kaurene Derivatives in Microsomes of the Immature Seed of Marah macrocarpus: Cofactor Requirements.
PubMed:
Biosynthesis of natural products. Part 1. Incorporations of ent-Kaur-16-ene and ent-Kaur-16-en-15-one into enmein and oridonin.