16-kaurene

kaur-16-ene

CAS: 562-28-7 C20 H32 MW: 272.47504000

Identification

Name16-kaurene
CAS Number562-28-7
FDA UNIISearch
Molecular FormulaC20 H32
Molecular Weight272.47504000

Regulatory

Physical Properties

Assay 92.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 346.00 to 348.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.000111 mmHg @ 25.00 °C. (est)
Flash Point 338.00 °F. TCC ( 170.00 °C. )
logP (o/w) 8.469 (est)
Soluble in alcohol
Insoluble in water

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryinformation only not used for fragrances or flavors
Recommendation for 16-kaurene usage levels up tonot for fragrance use.
Recommendation for 16-kaurene flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

barley microstrobos fitzgeraldii leaf oil australia @ 6.30% Data rice

Synonyms

kaur-16-ene (-)- kaur-16-ene PubMed: Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum. PubMed: Microbial transformation of the diterpene 7-epi-foliol by Fusarium fujikuroi. PubMed: Diterpenes and phenolic compounds from Sideritis pullulans. PubMed: Two new natural products from Croton kongensis Gagnep. PubMed: Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations. PubMed: [Chemical constituents from seeds of Vigna umbellata]. PubMed: Headspace, solid-phase micro-extraction, gas chromatographic-mass spectrometric analysis of terpenoids in the latex of Euphorbia species. PubMed: Cytotoxic and apoptosis-inducing activities of steviol and isosteviol derivatives against human cancer cell lines. PubMed: Biotransformation of ent-kaur-16-ene and ent-trachylobane 7β-acetoxy derivatives by the fungus Gibberella fujikuroi (Fusarium fujikuroi). PubMed: Chemical composition and antitermitic activity against Coptotermes formosanus Shiraki of Cryptomeria japonica leaf essential oil. PubMed: Determination and potential importance of diterpene (kaur-16-ene) emitted from dominant coniferous trees in Japan. PubMed: Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MS. PubMed: Analgesic and anti-inflammatory activities of 18-acetoxy-ent-kaur-16-ene from Annona squamosa L. bark. PubMed: 15α,20β-Dihydr-oxy-6β-meth-oxy-6,7-seco-6,20-ep-oxy-1,7-olide-ent-kaur-16-ene. PubMed: 6β,15β-Diacet-oxy-1β,7β,13α-trihydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene. PubMed: 1α,6β,7β,11α,15β-Penta-hydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene. PubMed: 6β-Acet-oxy-1α,7β,11β,15β-tetra-hydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene. PubMed: Cholinesterase and BACE1 inhibitory diterpenoids from Aralia cordata. PubMed: Chemical constituents of Isodon nervosus and their cytotoxicity. PubMed: Comparison of chemical compositions and antimicrobial activities of essential oils from three conifer trees; Pinus densiflora, Cryptomeria japonica, and Chamaecyparis obtusa. PubMed: An ent-kaurane diterpenoid from Isodon japonica var. glaucocalyx. PubMed: 1α,6β,7β,14β,15β-Penta-hydr-oxy-7α,20-ep-oxy-ent-kaur-16-ene. PubMed: Antiacetylcholinesterase and antioxidant ent-Kaurene diterpenoid, melissoidesin from Isodon wightii (Bentham) H. Hara. PubMed: Diterpenoids from the roots of Suregada glomerulata. PubMed: Isolation and biological activity of new and known isolation and biological activity of new and known diterpenoids from Sideritis stricta Boiss. & Heldr. PubMed: ent-Kaurenoids from the roots of Cacalia pilgeriana. PubMed: The microbiological transformation of 7alpha-hydroxy-ent-kaur-16-ene derivatives by Gibberella fujikuroi. PubMed: Antibacterial diterpenoids from Sagittaria pygmaea. PubMed: Functional characterization of the rice kaurene synthase-like gene family. PubMed: Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora. PubMed: Major volatile constituents of Annona squamosa L. bark. PubMed: Sylviside, a diterpene glucoside derivative from Gnaphalium sylvaticum. PubMed: Mono and diterpene production in Escherichia coli. PubMed: The microbiological transformation of two 15beta-hydroxy-ent-kaurene diterpenes by Gibberella fujikuroi. PubMed: Composition and antimicrobial activity of the essential oils from invasive species of the Azores, Hedychium gardnerianum and Pittosporum undulatum. PubMed: On the ent-kaurene diterpenes from Sideritis athoa. PubMed: Microbial transformation of 18-hydroxy-9,13-epi-ent-pimara-7,15-diene by Gibberella fujikuroi. PubMed: Biotransformation of the diterpenes epicandicandiol and candicandiol by Mucor plumbeus. PubMed: ent-Kaurene and squalene synthesis in Fusarium fujikuroi cell-free extracts. PubMed: The steam volatile oil of Wollemia nobilis and its comparison with other members of the Araucariaceae (Agathis and Araucaria). PubMed: A new diterpene glycoside from Rabdosia rubescens. PubMed: Diterpenoids from isodon eriocalyx PubMed: Megathyrin B: a cytotoxic diterpene from Isodon megathyrsus. PubMed: Isolation of two cytotoxic diterpenes from the fern Pteris multifida. PubMed: Antimicrobial activity of natural and semisynthetic diterpenoids from Sideritis spp. PubMed: Biosynthesis of rice phytoalexins: identification of putative diterpene hydrocarbon precursors. PubMed: Structure Elucidation of Inflexarabdonins G and H: Two New Diterpenoids from Rabdosia inflexa. PubMed: Isolation of gibberellin precursors from heavily pigmented tissues. PubMed: ent-Kaurene Biosynthesis in Cell-Free Extracts of Excised Parts of Tall and Dwarf Pea Seedlings. PubMed: Relationship between Chloroplast Development and ent-Kaurene Biosynthesis in Peas. PubMed: Diterpene biosynthesis in maize seedlings in response to fungal infection. PubMed: Studies on the Specificity and Site of Action of alpha-Cyclopropyl-alpha-[p-methoxyphenyl]-5-pyrimidine Methyl Alcohol (Ancymidol), a Plant Growth Regulator. PubMed: Properties of the System for the Mixed Function Oxidation of Kaurene and Kaurene Derivatives in Microsomes of the Immature Seed of Marah macrocarpus: Electron Transfer Components. PubMed: Properties of the System for the Mixed Function Oxidation of Kaurene and Kaurene Derivatives in Microsomes of the Immature Seed of Marah macrocarpus: Cofactor Requirements. PubMed: Biosynthesis of natural products. Part 1. Incorporations of ent-Kaur-16-ene and ent-Kaur-16-en-15-one into enmein and oridonin.