lenthionine
1,2,3,5,6-pentathiepane
Identification
| Name | lenthionine |
| CAS Number | 292-46-6 |
| FDA UNII | 71G9U1CIRD |
| Molecular Formula | C2 H4 S5 |
| Molecular Weight | 188.37888000 |
| MDL Number | MFCD03840531 |
| Nikkaji Number | J5.458E |
| CoE Number | 11619 |
Regulatory
| DG SANTE Food Flavourings | 15.081 lenthionine |
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 61.00 °C. @ 760.00 mm Hg |
| Boiling Point | 287.00 °C. @ 760.00 mm Hg |
| Vapor Pressure | 0.000082 mmHg @ 25.00 °C. (est) |
| Flash Point | 374.00 °F. TCC ( 190.00 °C. ) |
| logP (o/w) | 4.238 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Organoleptic Properties
| Odor Description | mushroom |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | flavoring agents |
| Recommendation for lenthionine usage levels up to | not for fragrance use. |
| Maximised Survey-derived Daily Intakes (MSDI-EU) | 0.012 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI) | 78 (μg/person/day) |
| Threshold of Concern | 90 (μg/person/day) |
| Structure Class | III |
| Dairy products, excluding products of category 02.0 (01.0) | 0.20000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0) | 0.10000 |
| Edible ices, including sherbet and sorbet (03.0) | 0.20000 |
| Processed fruit (04.1) | 0.20000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2) | - |
| Confectionery (05.0) | 0.20000 |
| Chewing gum (05.3) | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0) | 0.10000 |
| Bakery wares (07.0) | 0.20000 |
| Meat and meat products, including poultry and game (08.0) | 0.10000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0) | 0.10000 |
| Eggs and egg products (10.0) | - |
| Sweeteners, including honey (11.0) | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0) | 0.10000 |
| Foodstuffs intended for particular nutritional uses (13.0) | - |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1) | 0.10000 |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2) | 0.20000 |
| Ready-to-eat savouries (15.0) | 0.40000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0) | 0.10000 |
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Potential Uses
Natural Occurrence
Synonyms
1,2,3,5,6-
pentathiepane
PubMed:
Contributions of non-volatile and volatile compounds to the umami taste and overall flavour of shiitake mushroom extracts and their application as flavour enhancers in cooked minced meat.
PubMed:
A scent of therapy: pharmacological implications of natural products containing redox-active sulfur atoms.
PubMed:
Mini-laparotomy for repair of infrarenal abdominal aortic aneurysm.
PubMed:
Inhibitory activity of shiitake flavor against platelet aggregation.
PubMed:
The influence of Lentinus edodes (Shiitake mushroom) preparations on bacteriological and morphological aspects of the small intestine in piglets.
PubMed:
Encapsulation of shiitake (Lenthinus edodes) flavors by spray drying.
PubMed:
Antibacterial effect of the culture fluid of Lentinus edodes mycelium grown in submerged liquid culture.
PubMed:
Degradation of L-djenkolate catalyzed by S-alkylcysteine alpha,beta-lyase from Pseudomonas putida.
PubMed:
The red algal-higher fungi phylogenetic link: the last ten years.
PubMed:
Isolation, structure, and synthesis of lenthionine and its analogs.