quinic acid
cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3alpha,4alpha,5beta)-
Identification
| Name | quinic acid |
| IUPAC | (3S,5S)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid |
| CAS Number | 36413-60-2 |
| EINECS | 253-023-5 |
| FDA UNII | Search |
| Molecular Formula | C7 H12 O6 |
| Molecular Weight | 192.16784000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 438.42 °C. @ 760.00 mm Hg (est) |
| Flash Point | 452.00 °F. TCC ( 233.10 °C. ) (est) |
| logP (o/w) | -2.023 (est) |
| Soluble in | water, 1e+006 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | buffering agents |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | buffering agents |
| Recommendation for quinic acid usage levels up to | not for fragrance use. |
| Recommendation for quinic acid flavor usage levels up to | not for flavor use. |
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Exchange of knowledge
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Potential Uses
Natural Occurrence
Synonyms
cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3alpha,4alpha,5beta)-
L-
quinic acid
laevo-
quinic acid
(1alpha,3alpha,4alpha,5beta)-1,3,4,5-
tetrahydroxycyclohexane carboxylic acid
(3S,5S)-1,3,4,5-
tetrahydroxycyclohexane-1-carboxylic acid
(3s,5s)-1,3,4,5-
tetrahydroxycyclohexanecarboxylic acid
1,3,4,5-
tetrahydroxycyclohexanecarboxylic acid (1alpha,3alpha,4alpha,5beta)-
PubMed:
Herbal products containing Hibiscus sabdariffa L., Crataegus spp., and Panax spp.: Labeling and safety concerns.
PubMed:
Phenolic compounds from three brown seaweed species using LC-DAD-ESI-MS/MS.
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Potential effect of compounds isolated from Coffea arabica against UV-B induced skin damage by protecting fibroblast cells.
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LC-ESI-TOF-MS and GC-MS profiling of Artemisia herba-alba and evaluation of its bioactive properties.
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Extraction, identification and assessment of antioxidative compounds of bran extracts of traditional rice cultivars: An analytical approach.
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UVA, UVB Light Doses and Harvesting Time Differentially Tailor Glucosinolate and Phenolic Profiles in Broccoli Sprouts.
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Assessment of Antimicrobial and Antioxidant Activities of Nepeta trachonitica: Analysis of Its Phenolic Compounds Using HPLC-MS/MS.
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A robust platform based on ultra-high performance liquid chromatography Quadrupole time of flight tandem mass spectrometry with a two-step data mining strategy in the investigation, classification, and identification of chlorogenic acids in Ainsliaea fragrans Champ.
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UHPLC-Q-Orbitrap-HRMS-based global metabolomics reveal metabolome modifications in plasma of young women after cranberry juice consumption.
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An Unambiguous Nomenclature for the Acyl-quinic Acids Commonly Known as Chlorogenic Acids.
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Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome.
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Bioactive Components and Antioxidant Capacity of Fruits from Nine Sorbus Genotypes.
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An Efficient Method for the Preparative Isolation and Purification of Flavonoid Glycosides and Caffeoylquinic Acid Derivatives from Leaves of Lonicera japonica Thunb. Using High Speed Counter-Current Chromatography (HSCCC) and Prep-HPLC Guided by DPPH-HPLC Experiments.
PubMed:
Chemical Composition and Antioxidant Activity of Euterpe oleracea Roots and Leaflets.
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Hydrolysis of Dicaffeoylquinic Acids from Ilex kudingcha Happens in the Colon by Intestinal Microbiota.
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NMR metabolomics demonstrates phenotypic plasticity of sea buckthorn (Hippophaë rhamnoides) berries with respect to growth conditions in Finland and Canada.
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Selective enzymatic hydrolysis of chlorogenic acid lactones in a model system and in a coffee extract. Application to reduction of coffee bitterness.
PubMed:
Inhibitory effect of chlorogenic acid on digestion of potato starch.
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Four New Dicaffeoylquinic Acid Derivatives from Glasswort (Salicornia herbacea L.) and Their Antioxidative Activity.
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HPLC-DAD-ESI-MS(2) analytical profile of extracts obtained from purple sweet potato after green ultrasound-assisted extraction.
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Immobilized tannase treatment alters polyphenolic composition in teas and their potential anti-obesity and hypoglycemic activities in vitro.
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Rapid Identification and Comparison of Compounds with Antioxidant Activity in Coreopsis tinctoria Herbal Tea by High-Performance Thin-Layer Chromatography Coupled with DPPH Bioautography and Densitometry.
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Synthesis, Structure, and Tandem Mass Spectrometric Characterization of the Diastereomers of Quinic Acid.
PubMed:
Salinity effect on nutritional value, chemical composition and bioactive compounds content of Cichorium spinosum L.
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Analysis of a series of chlorogenic acid isomers using differential ion mobility and tandem mass spectrometry.
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Profiling Taste and Aroma Compound Metabolism during Apricot Fruit Development and Ripening.
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Facile Separation of 5-O-Galloylquinic Acid from Chinese Green Tea Extract using Mesoporous Zirconium Phosphate.
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Identification of Phenolic Compounds in Red and Green Pistachio (Pistacia vera L.) Hulls (Exo- and Mesocarp) by HPLC-DAD-ESI-(HR)-MS(n).
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Phenolic Profile and Antioxidant Potential of Leaves from Selected Cotoneaster Medik. Species.
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Characterisation of phenolic antioxidants in Scabiosa arenaria flowers by LC-ESI-MS/MS and NMR.
PubMed:
Comparative study of the antioxidative activities of caffeoylquinic and caffeic acids.
PubMed:
In vitro assessment of potential intestinal absorption of some phenolic families and carboxylic acids from commercial instant coffee samples.
PubMed:
A novel procedure for the assessment of the antioxidant capacity of food components.
PubMed:
Phytochemical Analysis and Antifungal Activity of Extracts from Leaves and Fruit Residues of Brazilian Savanna Plants Aiming Its Use as Safe Fungicides.
PubMed:
Anti-inflammatory and anti-oxidant effect of Calea urticifolia lyophilized aqueous extract on lipopolysaccharide-stimulated RAW 264.7 macrophages.
PubMed:
Antioxidants and α-glucosidase inhibitors from Ipomoea batatas leaves identified by bioassay-guided approach and structure-activity relationships.
PubMed:
Microbial biotransformation of polyphenols during in vitro colonic fermentation of masticated mango and banana.
PubMed:
Phenolic acid degradation potential and growth behavior of lactic acid bacteria in sunflower substrates.
PubMed:
Hydrophilic antioxidants from Andean tomato landraces assessed by their bioactivities in vitro and in vivo.
PubMed:
Development of Marker-Free Transgenic Potato Tubers Enriched in Caffeoylquinic Acids and Flavonols.
PubMed:
Phenolic Profile and Biological Activities of the Pepino (Solanum muricatum) Fruit and Its Wild Relative S. caripense.
PubMed:
Distribution of Major Chlorogenic Acids and Related Compounds in Brazilian Green and Toasted Ilex paraguariensis (Maté) Leaves.
PubMed:
Metabolic Response of Strawberry (Fragaria x ananassa) Leaves Exposed to the Angular Leaf Spot Bacterium (Xanthomonas fragariae).
PubMed:
Chlorogenic acid ameliorates intestinal mitochondrial injury by increasing antioxidant effects and activity of respiratory complexes.
PubMed:
Fresh from the Ornamental Garden: Hips of Selected Rose Cultivars Rich in Phytonutrients.
PubMed:
Dicaffeoylquinic Acid-Enriched Fraction of Cichorium glandulosum Seeds Attenuates Experimental Type 1 Diabetes via Multipathway Protection.
PubMed:
Antiamnesic Effect of Actinidia arguta Extract Intake in a Mouse Model of TMT-Induced Learning and Memory Dysfunction.
PubMed:
Matching in Vitro Bioaccessibility of Polyphenols and Antioxidant Capacity of Soluble Coffee by Boosted Regression Trees.
PubMed:
Fruit Phenolic Composition of Different Elderberry Species and Hybrids.
PubMed:
Flavonoids and Methoxy-galloylquinic Acid Derivatives from the Leaf Extract of Copaifera langsdorffii Desf.
PubMed:
Caffeoylquinic acids competitively inhibit pancreatic lipase through binding to the catalytic triad.
PubMed:
Effect of 5-caffeoylquinic acid on the NF-κB signaling pathway, peroxisome proliferator-activated receptor gamma 2, and macrophage infiltration in high-fat diet-fed Sprague-Dawley rat adipose tissue.
PubMed:
Neochlorogenic Acid Inhibits Lipopolysaccharide-Induced Activation and Pro-inflammatory Responses in BV2 Microglial Cells.
PubMed:
Melissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterization.
PubMed:
Metal Complex Pigment Involved in the Blue Sepal Color Development of Hydrangea.
PubMed:
Determination of caffeoylquinic acids in feed and related products by focused ultrasound solid-liquid extraction and ultra-high performance liquid chromatography-mass spectrometry.
PubMed:
The effects of juice processing on black mulberry antioxidants.
PubMed:
Effect of repeated harvesting on the content of caffeic acid and seven species of caffeoylquinic acids in sweet potato leaves.
PubMed:
Chlorogenic acid-arabinose hybrid domains in coffee melanoidins: Evidences from a model system.
PubMed:
Chlorogenic acid stability in pressurized liquid extraction conditions.
PubMed:
Rapid Fingerprint Analysis of Plant Extracts for Ellagitannins, Gallic Acid, and Quinic Acid Derivatives and Quercetin-, Kaempferol- and Myricetin-Based Flavonol Glycosides by UPLC-QqQ-MS/MS.
PubMed:
Comprehensive 3-year study of the phenolic profile of Moroccan monovarietal virgin olive oils from the Meknès region.
PubMed:
Flavor of fresh blueberry juice and the comparison to amount of sugars, acids, anthocyanidins, and physicochemical measurements.
PubMed:
Parallel reductions in phenolic constituents resulting from the domestication of eggplant.
PubMed:
Inhibitory activities of caffeoylquinic acid derivatives from Ilex kudingcha C.J. Tseng on α-glucosidase from Saccharomyces cerevisiae.
PubMed:
Effects of caffeic and 5-caffeoylquinic acids on cell viability and cellular uptake in human colon adenocarcinoma cells.
PubMed:
Characterization and quantitative analysis of phenylpropanoid amides in eggplant (Solanum melongena L.) by high performance liquid chromatography coupled with diode array detection and hybrid ion trap time-of-flight mass spectrometry.
PubMed:
Polyphenols from artichoke heads (Cynara cardunculus (L.) subsp. scolymus Hayek): in vitro bio-accessibility, intestinal uptake and bioavailability.
PubMed:
(1S,3R,4S,5R)5-O-Caffeoylquinic acid: isolation, stereo-structure characterization and biological activity.
PubMed:
Solvent system selectivities in countercurrent chromatography using Salicornia gaudichaudiana metabolites as practical example with off-line electrospray mass-spectrometry injection profiling.
PubMed:
Role of degradation products of chlorogenic acid in the antioxidant activity of roasted coffee.
PubMed:
Anthocyanins and antioxidant capacities of six Chilean berries by HPLC-HR-ESI-ToF-MS.
PubMed:
Antioxidant components of Viburnum opulus L. determined by on-line HPLC-UV-ABTS radical scavenging and LC-UV-ESI-MS methods.
PubMed:
Metabolism of phenolic compounds by Lactobacillus spp. during fermentation of cherry juice and broccoli puree.
PubMed:
Changes in sugars and organic acids in wolfberry (Lycium barbarum L.) fruit during development and maturation.
PubMed:
Carboxymethyl- and carboxyl-catechins from ripe Pu-er tea.
PubMed:
In vitro enzymic hydrolysis of chlorogenic acids in coffee.
PubMed:
Influence of sulfur fumigation on the chemical constituents and antioxidant activity of buds of Lonicera japonica.
PubMed:
Transformation of 5-O-caffeoylquinic acid in blueberries during high-temperature processing.
PubMed:
Dual catalytic activity of hydroxycinnamoyl-coenzyme A quinate transferase from tomato allows it to moonlight in the synthesis of both mono- and dicaffeoylquinic acids.
PubMed:
Identification and characterization of chlorogenic acids, chlorogenic acid glycosides and flavonoids from Lonicera henryi L. (Caprifoliaceae) leaves by LC-MSn.
PubMed:
5-Caffeoylquinic acid decreases diet-induced obesity in rats by modulating PPARα and LXRα transcription.
PubMed:
Interaction of chlorogenic acids and quinides from coffee with human serum albumin.
PubMed:
Effects of domestic cooking methods on polyphenols and antioxidant activity of sweet potato leaves.
PubMed:
Thermal transformation of trans-5-O-caffeoylquinic acid (trans-5-CQA) in alcoholic solutions.
PubMed:
Investigation of acyl migration in mono- and dicaffeoylquinic acids under aqueous basic, aqueous acidic, and dry roasting conditions.
PubMed:
Single-laboratory validation for the determination of caffeic acid and seven caffeoylquinic acids in sweet potato leaves.
PubMed:
Precursor ion scan driven fast untargeted screening and semi-determination of caffeoylquinic acid derivatives in Cynara scolymus L.
PubMed:
A rapid method for quantifying chlorogenic acid levels in potato samples.
PubMed:
Inhibition by caffeic acid of the influenza A virus multiplication in vitro.
PubMed:
Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking?
PubMed:
Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study.
PubMed:
Water scarcity conditions affect peach fruit size and polyphenol contents more severely than other fruit quality traits.
PubMed:
Impact of dose on the bioavailability of coffee chlorogenic acids in humans.
PubMed:
Chemical analysis and antihyperglycemic activity of an original extract from burdock root (Arctium lappa).
PubMed:
Sweet potato (Ipomoea batatas [L.] Lam)--a valuable medicinal food: a review.
PubMed:
Metabolic engineering of Escherichia coli for improving shikimate synthesis from glucose.
PubMed:
Identification and quantitative determination of the polar constituents in Helichrysum italicum flowers and derived food supplements.
PubMed:
Consumption of a dark roast coffee decreases the level of spontaneous DNA strand breaks: a randomized controlled trial.
PubMed:
Identification of α-glucosidase inhibitors from the leaves of Pluchea indica (L.) Less., a traditional Indonesian herb: promotion of natural product use.
PubMed:
Evolution of polyphenols and organic acids during the fermentation of apple cider.
PubMed:
In vitro transformation of chlorogenic acid by human gut microbiota.
PubMed:
Effects of boiling on chlorogenic acid and the liver protective effects of its main products against CClâ-induced toxicity in vitro.
PubMed:
Preparative isolation of aldose reductase inhibitory compounds from Nardostachys chinensis by elution-extrusion counter-current chromatography.
PubMed:
Persea americana Mill. Seed: Fractionation, Characterization, and Effects on Human Keratinocytes and Fibroblasts.
PubMed:
On-line process monitoring of coffee roasting by resonant laser ionisation time-of-flight mass spectrometry: bridging the gap from industrial batch roasting to flavour formation inside an individual coffee bean.
PubMed:
Inhibition of the β-catenin/Tcf signaling by caffeoylquinic acids in sweet potato leaf through down regulation of the Tcf-4 transcription.
PubMed:
Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform.
PubMed:
Quantitative studies on roast kinetics for bioactives in coffee.
PubMed:
Impact of chemical changes on the sensory characteristics of coffee beans during storage.
PubMed:
Gymnaster koraiensis and its major components, 3,5-di-O-caffeoylquinic acid and gymnasterkoreayne B, reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cells.
PubMed:
Metabolic differentiation of diamondback moth ( Plutella xylostella (L.)) resistance in cabbage ( Brassica oleracea L. ssp. capitata).
PubMed:
Phenolic profile and antioxidant activity of Serbian polyfloral honeys.
PubMed:
Dried plums and their products: composition and health effects--an updated review.
PubMed:
Antioxidant and genoprotective effects of spent coffee extracts in human cells.
PubMed:
Resistance to the weevils Cylas puncticollis and Cylas brunneus conferred by sweetpotato root surface compounds.
PubMed:
Citron and lemon under the lens of HR-MAS NMR spectroscopy.
PubMed:
Identification and quantification of free, conjugate and total phenolic compounds in leaves of 20 sweetpotato cultivars by HPLC-DAD and HPLC-ESI-MS/MS.
PubMed:
A new method for the preparative isolation of chlorogenic acid lactones from coffee and model roasts of 5-caffeoylquinic acid.
PubMed:
Milk whey protein modification by coffee-specific phenolics: effect on structural and functional properties.
PubMed:
An outlook on chlorogenic acids-occurrence, chemistry, technology, and biological activities.
PubMed:
Anti-Aspergillus activity of green coffee 5-O-caffeoyl quinic acid and its alkyl esters.
PubMed:
Caffeoylquinic acid-rich purple sweet potato extract, with or without anthocyanin, imparts neuroprotection and contributes to the improvement of spatial learning and memory of SAMP8 mouse.
PubMed:
Aldose reductase inhibitory compounds from Xanthium strumarium.
PubMed:
Diversity of (dihydro) hydroxycinnamic acid conjugates in Colombian potato tubers.
PubMed:
The impact of Ca2+ combination with organic acids on green tea infusions.
PubMed:
Structure- and dose-absorption relationships of coffee polyphenols.
PubMed:
Characterization of genes for a putative hydroxycinnamoyl-coenzyme A quinate transferase and p-coumarate 3'-hydroxylase and chlorogenic acid accumulation in tartary buckwheat.
PubMed:
HPLC-DAD-ESI/MS identification and quantification of phenolic compounds in Ilex paraguariensis beverages and on-line evaluation of individual antioxidant activity.
PubMed:
Absorption and isomerization of caffeoylquinic acids from different foods using ileostomist volunteers.
PubMed:
Bioavailability of dietary (poly)phenols: a study with ileostomists to discriminate between absorption in small and large intestine.
PubMed:
Metabolic profiling of Chinese tobacco leaf of different geographical origins by GC-MS.
PubMed:
Carotenoids and phenolic compounds from Solanum sessiliflorum, an unexploited Amazonian fruit, and their scavenging capacities against reactive oxygen and nitrogen species.
PubMed:
Determination of α-hydroxy acids and their enantiomers in fruit juices by ligand exchange CE with a dual central metal ion system.
PubMed:
Radical scavenging activity and cytotoxicity of active quinic acid derivatives from Scorzonera divaricata roots.
PubMed:
Identification of organic acids in Cichorium intybus inhibiting virulence-related properties of oral pathogenic bacteria.
PubMed:
Adhesive microbeads for the targeting delivery of anticaries agents of vegetable origin.
PubMed:
Polyphenolics composition of the leaves of Zanthoxylum bungeanum Maxim. grown in Hebei, China, and their radical scavenging activities.
PubMed:
Quantitative fate of chlorogenic acid during enzymatic browning of potato juice.
PubMed:
Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: the PREDIMED study.
PubMed:
Degradation kinetics of chlorogenic acid at various pH values and effects of ascorbic acid and epigallocatechin gallate on its stability under alkaline conditions.
PubMed:
Biotransformation of 4,5-O-dicaffeoylquinic acid methyl ester by human intestinal flora and evaluation on their inhibition of NO production and antioxidant activity of the products.
PubMed:
Characterization of Changes in Polyphenols, Antioxidant Capacity and Physico-Chemical Parameters during Lowbush Blueberry Fruit Ripening.
PubMed:
Radioprotection by two phenolic compounds: chlorogenic and quinic acid, on X-ray induced DNA damage in human blood lymphocytes in vitro.
PubMed:
Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb. leaves.
PubMed:
Ni speciation in tea infusions by monolithic chromatography--ICP-MS and Q-TOF-MS.
PubMed:
Evaluation of spent coffee obtained from the most common coffeemakers as a source of hydrophilic bioactive compounds.
PubMed:
Comparative evaluation of cultivars of Chrysanthemum morifolium flowers by HPLC-DAD-ESI/MS analysis and antiallergic assay.
PubMed:
Formation of ester and amine derivatives of 5-O-caffeoylquinic acid in the process of its simulated extraction.
PubMed:
Identification of phenolic constituents in Cichorium endivia var. crispum and var. latifolium salads by high-performance liquid chromatography with diode array detection and electrospray ioniziation tandem mass spectrometry.
PubMed:
Inhibitory activity of Aralia continentalis roots on protein tyrosine phosphatase 1B and rat lens aldose reductase.
PubMed:
Antioxidant and DNA-protective activities of chlorogenic acid isomers.
PubMed:
Peach fruit: metabolic comparative analysis of two varieties with different resistances to insect attacks by NMR spectroscopy.
PubMed:
Identification and quantification of constituents of Gardenia jasminoides Ellis (Zhizi) by HPLC-DAD-ESI-MS.
PubMed:
Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro.
PubMed:
Investigating the chemical changes of chlorogenic acids during coffee brewing: conjugate addition of water to the olefinic moiety of chlorogenic acids and their quinides.
PubMed:
Effects of temperature and photoperiod on yield and chemical composition of northern and southern clones of bilberry (Vaccinium myrtillus L.).
PubMed:
(13)C NMR-based metabolomics for the classification of green coffee beans according to variety and origin.
PubMed:
Effect of coffee combining green coffee bean constituents with typical roasting products on the Nrf2/ARE pathway in vitro and in vivo.
PubMed:
Characterization of the polymerization of furfuryl alcohol during roasting of coffee.
PubMed:
Anti-inflammatory and anti-angiogenic effects of flavonoids isolated from Lycium barbarum Linnaeus on human umbilical vein endothelial cells.
PubMed:
Effect of maturation and cold storage on the organic acid composition of myrtle fruits.
PubMed:
Content of antioxidative caffeoylquinic acid derivatives in field-grown Ligularia fischeri (Ledeb.) Turcz and responses to sunlight.
PubMed:
The anticarcinogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.).
PubMed:
Comparative analysis of caffeoylquinic acids and lignans in roots and seeds among various burdock (Arctium lappa) genotypes with high antioxidant activity.
PubMed:
Chemical descriptors for sensory and parental origin of commercial Coffea genotypes.
PubMed:
Ultraviolet-B light treatment increases antioxidant capacity of carrot products.
PubMed:
Effects of genotype, latitude, and weather conditions on the composition of sugars, sugar alcohols, fruit acids, and ascorbic acid in sea buckthorn (Hippophaë rhamnoides ssp. mongolica) berry juice.
PubMed:
Polyphenol compounds in artichoke plant tissues and varieties.
PubMed:
Roasting process of coffee beans as studied by nuclear magnetic resonance: time course of changes in composition.
PubMed:
Identification of nutritional descriptors of roasting intensity in beverages of Arabica and Robusta coffee beans.
PubMed:
Food components with anticaries activity.
PubMed:
Caffeoylquinic acid-rich extract from chicory seeds improves glycemia, atherogenic index, and antioxidant status in rats.
PubMed:
Investigation of isomeric transformations of chlorogenic acid in buffers and biological matrixes by ultraperformance liquid chromatography coupled with hybrid quadrupole/ion mobility/orthogonal acceleration time-of-flight mass spectrometry.
PubMed:
Identification of phenolic components in dried spices and influence of irradiation.
PubMed:
New insights into an ancient antibrowning agent: formation of sulfophenolics in sodium hydrogen sulfite-treated potato extracts.
PubMed:
Characterization and quantification of hydroxycinnamate derivatives in Stevia rebaudiana leaves by LC-MSn.
PubMed:
Two new antioxidant malonated caffeoylquinic acid isomers in fruits of wild eggplant relatives.
PubMed:
Two-dimensional 1H-13C nuclear magnetic resonance (NMR)-based comprehensive analysis of roasted coffee bean extract.
PubMed:
Hydrolysis influence on phytochemical composition, antioxidant activity, plasma concentration, and tissue distribution of hydroethanolic Ilex paraguariensis extract components.
PubMed:
Caffeoylquinic acid derived free radicals identified during antioxidant reactions of bitter tea (Ilex latifolia and Ilex kudincha).
PubMed:
Identification and characterization of five new classes of chlorogenic acids in burdock (Arctium lappa L.) roots by liquid chromatography/tandem mass spectrometry.
PubMed:
Antioxidative caffeoylquinic acids and flavonoids from Hemerocallis fulva flowers.
PubMed:
Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction.
PubMed:
Rapid identification and evaluation of antioxidant compounds from extracts of Petasites japonicus by hyphenated-HPLC techniques.
PubMed:
Metabolic fingerprinting reveals differences between shoots of wild and cultivated carrot (Daucus carota L.) and suggests maternal inheritance or wild trait dominance in hybrids.
PubMed:
Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages.
PubMed:
Neuroprotective effect of caffeoylquinic acids from Artemisia princeps Pampanini against oxidative stress-induced toxicity in PC-12 cells.
PubMed:
Analysis of eleven phenolic compounds including novel p-coumaroyl derivatives in lettuce (Lactuca sativa L.) by ultra-high-performance liquid chromatography with photodiode array and mass spectrometry detection.
PubMed:
First chemical synthesis and in vitro characterization of the potential human metabolites 5-o-feruloylquinic acid 4'-sulfate and 4'-O-glucuronide.
PubMed:
Colonic availability of polyphenols and D-(-)-quinic acid after apple smoothie consumption.
PubMed:
Intestinal transit and systemic metabolism of apple polyphenols.
PubMed:
Thermal stability of 5-o-caffeoylquinic acid in aqueous solutions at different heating conditions.
PubMed:
Antiproliferation effect of commercially brewed coffees on human ovarian cancer cells in vitro.
PubMed:
Polyphenols-rich Vernonia amygdalina shows anti-diabetic effects in streptozotocin-induced diabetic rats.
PubMed:
Profiling and characterisation by liquid chromatography/multi-stage mass spectrometry of the chlorogenic acids in Gardeniae Fructus.
PubMed:
Enantioseparation of DL-isocitric acid by a chiral ligand exchange CE with Ni(II)-D-quinic acid system.
PubMed:
New 5-O-caffeoylquinic acid derivatives in fruit of the wild eggplant relative Solanum viarum.
PubMed:
Geographical and climatic dependencies of green tea (Camellia sinensis) metabolites: a (1)H NMR-based metabolomics study.
PubMed:
Rapid determination of caffeoylquinic acid derivatives in Cynara scolymus L. by ultra-fast liquid chromatography/tandem mass spectrometry based on a fused core C18 column.
PubMed:
Isolation and identification of antioxidant compounds from Ligularia fischeri.
PubMed:
Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression.
PubMed:
Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell lines.
PubMed:
Isolation and quantitative analysis of peroxynitrite scavengers from Artemisia princeps var. orientalis.
PubMed:
Phenolic acids and methylxanthines composition and antioxidant properties of mate (Ilex paraguariensis) residue.
PubMed:
Formation of volatile chemicals from thermal degradation of less volatile coffee components: quinic acid, caffeic acid, and chlorogenic acid.
PubMed:
Identifications of inhibitors of IgE production by human lymphocytes isolated from 'Cha Chuukanbohon Nou 6' tea leaves.
PubMed:
Anti-ulcerogenic effect and HPLC analysis of the caffeoylquinic acid-rich extract from Ligularia stenocephala.
PubMed:
Quantitative studies on the influence of the bean roasting parameters and hot water percolation on the concentrations of bitter compounds in coffee brew.
PubMed:
Global regulation of food supply by Pseudomonas putida DOT-T1E.
PubMed:
Acids, sugars, and sugar alcohols in Chinese hawthorn (Crataegus spp.) fruits.
PubMed:
Angiostatic effects of Brazilian green propolis and its chemical constituents.
PubMed:
Chemical kinetics of 5-o-caffeoylquinic acid in superheated steam: effect of isomerization on mate (Ilex paraguariensis) manufacturing.
PubMed:
Application of metabolomics in the analysis of manufacturing type of pu-erh tea and composition changes with different postfermentation year.
PubMed:
Kinetic analysis and mechanism on the inhibition of chlorogenic acid and its components against porcine pancreas alpha-amylase isozymes I and II.
PubMed:
Ficus carica L.: Metabolic and biological screening.
PubMed:
A novel method for the quantification of quinic acid in food using stable isotope dilution analysis.
PubMed:
Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
PubMed:
Effects of latitude and weather conditions on contents of sugars, fruit acids, and ascorbic acid in black currant (Ribes nigrum L.) juice.
PubMed:
Organic acids composition of Cydonia oblonga Miller leaf.
PubMed:
Elucidation of the mechanism of enzymatic browning inhibition by sodium chlorite.
PubMed:
Identification of hydroxycinnamoylquinic acids of arnica flowers and burdock roots using a standardized LC-DAD-ESI/MS profiling method.
PubMed:
Structure determination of 3-O-caffeoyl-epi-gamma-quinide, an orphan bitter lactone in roasted coffee.
PubMed:
Identification of the antimicrobial substances produced by Solanum palinacanthum (Solanaceae).
PubMed:
Effects of different cooking methods on antioxidant profile, antioxidant capacity, and physical characteristics of artichoke.
PubMed:
Stress-induced biosynthesis of dicaffeoylquinic acids in globe artichoke.
PubMed:
Roasting effects on formation mechanisms of coffee brew melanoidins.
PubMed:
Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.
PubMed:
Phenolic antioxidants from green tea produced from Camellia taliensis.
PubMed:
Electron spin resonance (ESR) studies on the formation of roasting-induced antioxidative structures in coffee brews at different degrees of roast.
PubMed:
Low molecular weight melanoidins in coffee brew.
PubMed:
5-caffeoylquinic acid and caffeic acid down-regulate the oxidative stress- and TNF-alpha-induced secretion of interleukin-8 from Caco-2 cells.
PubMed:
Human glycemic response and phenolic content of unsweetened cranberry juice.
PubMed:
Antiviral activities of coffee extracts in vitro.
PubMed:
Antioxidant properties of sour cherries (Prunus cerasus L.): role of colorless phytochemicals from the methanolic extract of ripe fruits.
PubMed:
Incorporation of chlorogenic acids in coffee brew melanoidins.
PubMed:
Impact of fermentation on phenolic compounds in leaves of pak choi (Brassica campestris L. ssp. chinensis var. communis) and Chinese leaf mustard (Brassica juncea coss).
PubMed:
Polyphenols are intensively metabolized in the human gastrointestinal tract after apple juice consumption.
PubMed:
Changes in polyphenolic content and radical-scavenging activity of sweet potato (Ipomoea batatas L.) during storage at optimal and low temperatures.
PubMed:
Phenolic antioxidants identified by ESI-MS from Yerba maté (Ilex paraguariensis) and green tea (Camelia sinensis) extracts.
PubMed:
Identification of flavonoids and hydroxycinnamic acids in pak choi varieties (Brassica campestris L. ssp. chinensis var. communis) by HPLC-ESI-MSn and NMR and their quantification by HPLC-DAD.
PubMed:
Formation of the thiocyanate conjugate of chlorogenic acid in coffee under acidic conditions in the presence of thiocyanate and nitrite: possible occurrence in the stomach.
PubMed:
[Simultaneous determination of twenty-one organic acids in food by ion chromatography with eluent autogeneration].
PubMed:
Enhancing the oxidative stability of rice crackers by addition of the ethanolic extract of phytochemicals from Cratoxylum formosum Dyer.
PubMed:
Profiling and characterization by LC-MSn of the galloylquinic acids of green tea, tara tannin, and tannic acid.
PubMed:
Hepatoprotective and antioxidative effects of total phenolics from Laggera pterodonta on chemical-induced injury in primary cultured neonatal rat hepatocytes.
PubMed:
Profiling the chlorogenic acids and other caffeic acid derivatives of herbal chrysanthemum by LC-MSn.
PubMed:
Quantitative precursor studies on di- and trihydroxybenzene formation during coffee roasting using "in bean" model experiments and stable isotope dilution analysis.
PubMed:
Profiling the chlorogenic acids of aster by HPLC-MS(n).
PubMed:
Quantitative determination of phenolic compounds in artichoke-based dietary supplements and pharmaceuticals by high-performance liquid chromatography.
PubMed:
New polyphenol derivative in Ipomoea batatas tubers and its antioxidant activity.
PubMed:
Changes in organic acids and sugars during early stages of development of acidic and acidless citrus fruit.
PubMed:
Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum Thunb.
PubMed:
Characterization by LC-MS(n) of four new classes of p-coumaric acid-containing diacyl chlorogenic acids in green coffee beans.
PubMed:
Anti-human immunodeficiency virus activity of 3,4,5-tricaffeoylquinic acid in cultured cells of lettuce leaves.
PubMed:
Fast analysis of sugars, fruit acids, and vitamin C in sea buckthorn (Hippophaë rhamnoides L.) varieties.
PubMed:
Characterization by LC-MS(n) of four new classes of chlorogenic acids in green coffee beans: dimethoxycinnamoylquinic acids, diferuloylquinic acids, caffeoyl-dimethoxycinnamoylquinic acids, and feruloyl-dimethoxycinnamoylquinic acids.
PubMed:
Anti-hyperglycemic Potential of Natural Products.
PubMed:
Tungtungmadic acid, a novel antioxidant, from Salicornia herbacea.
PubMed:
Discriminating between the six isomers of dicaffeoylquinic acid by LC-MS(n).
PubMed:
Screening of raw coffee for thiol binding site precursors using "in bean" model roasting experiments.
PubMed:
Antioxidant properties of prunes (Prunus domestica L.) and their constituents.
PubMed:
A new glucosyl feruloyl quinic acid as a potential marker for roots and rhizomes of goldenseal, Hydrastis canadensis.
PubMed:
Characterization of cigarette tobacco by direct electrospray ionization-ion trap mass spectrometry (ESI-ITMS) analysis of the aqueous extract--a novel and simple approach.
PubMed:
Deodorization with ku-ding-cha containing a large amount of caffeoyl quinic acid derivatives.
PubMed:
Identification and quantification of caffeoylquinic acids and flavonoids from artichoke (Cynara scolymus L.) heads, juice, and pomace by HPLC-DAD-ESI/MS(n).
PubMed:
HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea.
PubMed:
In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee.
PubMed:
Metabolite profiling using (1)H NMR spectroscopy for quality assessment of green tea, Camellia sinensis (L.).
PubMed:
Inhibition of apple polyphenol oxidase activity by procyanidins and polyphenol oxidation products.
PubMed:
Changes in broccoli (Brassica oleracea L. Var. italica) health-promoting compounds with inflorescence development.
PubMed:
Health-promoting compounds in broccoli as influenced by refrigerated transport and retail sale period.
PubMed:
Hierarchical scheme for LC-MSn identification of chlorogenic acids.
PubMed:
Quantitative evaluation of antioxidant components in prunes (Prunus domestica L.).
PubMed:
Hydrophilic carboxylic acids and iridoid glycosides in the juice of American and European cranberries (Vaccinium macrocarpon and V. oxycoccos), lingonberries (V. vitis-idaea), and blueberries (V. myrtillus).
PubMed:
LC/MS/MS characterization of phenolic constituents in dried plums.
PubMed:
Inhibitory effects of plant phenols on the activity of selected enzymes.
PubMed:
Study of the organic acids composition of quince (Cydonia oblonga Miller) fruit and jam.
PubMed:
Processing effects on the composition of sea buckthorn juice from Hippophae rhamnoides L. Cv. Indian Summer.
PubMed:
Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
PubMed:
Identification and antioxidant activity of novel chlorogenic acid derivatives from bamboo (Phyllostachys edulis).
PubMed:
Isolation and characterization of human colonic bacteria able to hydrolyse chlorogenic acid.
PubMed:
Stability and bioavailability of antioxidants in garland (Chrysanthemum coronarium L.).
PubMed:
Stabilization of soybean oil with heated quercetin and 5-caffeoylquinic acid in the presence of ferric ion.
PubMed:
Thermodynamics of interaction of caffeic acid and quinic acid with multisubunit proteins.
PubMed:
Interaction of 3'-O-caffeoyl D-quinic acid with human serum albumin.
PubMed:
A comparative genotoxicity study of chlorogenic acid (3-0-caffeoylquinic acid).
PubMed:
Bound quinic acid as a measure of coupling of leaf and sunflower-seed proteins with chlorogenic acid congeners: loss of availability of lysine.
PubMed:
Identification and quantitative analysis of sugars and non-volatile organic acids in Chinese gooseberry fruit (Actinidia chinensis Planch.).
PubMed:
Determination of organic acids in foods by liquid chromatography.
PubMed:
(-)-3t,4t-Dihydroxycyclohexane-1c-carboxylate, a new quinate metabolite of Lactobacillus plantarum.
PubMed:
The metabolism of certain drugs and food chemicals in man.
PubMed:
Symposium on microbial changes in foods. Microbiological aspects of production and spoilage of cider.
PubMed:
Phenolic and sugar components of Armavirec variety sunflower (Helianthus annuus) seed meal.