pipecolinic acid

CAS: 535-75-1 C6 H11 N O2 MW: 129.15907000

Identification

Namepipecolinic acid
IUPACpiperidine-2-carboxylic acid
CAS Number535-75-1
EINECS208-616-3
FDA UNIIH254GW7PVV
Molecular FormulaC6 H11 N O2
Molecular Weight129.15907000
MDL NumberMFCD00064347
Nikkaji NumberJ1.592J
Beilstein0081095
XlogP3-2.30 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Soluble in water, 7.406e+004 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for pipecolinic acid usage levels up tonot for fragrance use.
Recommendation for pipecolinic acid flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

apple plant banana fruit bean adzuki bean seed bean black bean seed bean fava bean seed bean field bean carrot plant cherry sour cherry fruit date palm fruit eggplant fruit ginger rhizome lupine white lupine stem melon bitter melon fruit pea plant tamarind fruit tea fruit tomato fruit zingiber officinale root oil china @ 0.10% Data

Synonyms

dihydrobaikiane hexahydropicolinic acid pipecolic acid 2- piperidine carboxylic acid piperidine-2-carboxylic acid homo proline PubMed: The betaine profile of cereal flours unveils new and uncommon betaines. PubMed: Heat-induced formation of mepiquat by decarboxylation of pipecolic acid and its betaine derivative. Part 2: Natural formation in cooked vegetables and selected food products. PubMed: Heat-induced formation of mepiquat by decarboxylation of pipecolic acid and its betaine derivative. Part 1: Model system studies. PubMed: Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei. PubMed: Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity. PubMed: Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes. PubMed: Enantiomeric separation of non-protein amino acids by electrokinetic chromatography. PubMed: Homostachydrine (pipecolic acid betaine) as authentication marker of roasted blends of Coffea arabica and Coffea canephora (Robusta) beans. PubMed: Short-term toxicity assessments of an antibiotic metabolite in Wistar rats and its metabonomics analysis by ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. PubMed: Betaines and related ammonium compounds in chestnut (Castanea sativa Mill.). PubMed: Amino acid-derived betaines dominate as urinary markers for rye bran intake in mice fed high-fat diet--A nontargeted metabolomics study. PubMed: Identification and monitoring of metabolite markers of dry bean consumption in parallel human and mouse studies. PubMed: Regulation of free glutamate content in meat by dietary lysine in broilers. PubMed: Determination and stereochemistry of proteinogenic and non-proteinogenic amino acids in Saudi Arabian date fruits. PubMed: Obesity-related metabolomic analysis of human subjects in black soybean peptide intervention study by ultraperformance liquid chromatography and quadrupole-time-of-flight mass spectrometry. PubMed: Occurrence of pipecolic acid and pipecolic acid betaine (homostachydrine) in Citrus genus plants. PubMed: Metabolomic analysis of meju during fermentation by ultra performance liquid chromatography-quadrupole-time of flight mass spectrometry (UPLC-Q-TOF MS). PubMed: Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein. PubMed: Metabolomic analysis of livers and serum from high-fat diet induced obese mice. PubMed: A novel yellow pigment, furpipate, derived from lysine and furfural. PubMed: Browning of furfural and amino acids, and a novel yellow compound, furpipate, formed from lysine and furfural. PubMed: Applications of the ninhydrin reaction for analysis of amino acids, peptides, and proteins to agricultural and biomedical sciences. PubMed: Discrimination between arabica and robusta coffee species on the basis of their amino acid enantiomers. PubMed: Central pipecolic acid increases food intake under ad libitum feeding conditions in the neonatal chick. PubMed: Intracerebroventricular administration of GABA-A and GABA-B receptor antagonists attenuate feeding and sleeping-like behavior induced by L-pipecolic acid in neonatal chicks. PubMed: Determination of D- and L-pipecolic acid in food samples including processed foods. PubMed: Intracerebroventricular injection of pipecolic acid inhibits food intake and induces sleeping-like behaviors in the neonatal chick. PubMed: New and Convenient Syntheses of the Important Roasty, Popcorn-like Smelling Food Aroma Compounds 2-Acetyl-1-pyrroline and 2-Acetyltetrahydropyridine from Their Corresponding Cyclic alpha-Amino Acids. PubMed: Osmoprotectants and cryoprotectants for Listeria monocytogenes. PubMed: Origin of D- and L-pipecolic acid in human physiological fluids: a study of the catabolic mechanism to pipecolic acid using the lysine loading test. PubMed: GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior. PubMed: Rapid gas chromatographic screening of edible seeds, nuts and beans for non-protein and protein amino acids. PubMed: Analysis of free amino acids in green coffee beans. I. Determination of amino acids after precolumn derivatization using 9-fluorenylmethylchloroformate. PubMed: GABA transmission, but not benzodiazepine receptor stimulation, modulates ethanol intake by rats. PubMed: [On the chemotaxonomy of food plants :pipecolinic acid, a characteristic ingredient of grass silages]. PubMed: Proline control of the feeding reaction of Cordylophora.