norstictic acid
7H-2,6,12-trioxabenzo[5,6]cyclohept[1,2-e]indene-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-
Identification
| Name | norstictic acid |
| CAS Number | 571-67-5 |
| FDA UNII | Search |
| Molecular Formula | C18 H12 O9 |
| Molecular Weight | 372.28644000 |
| MDL Number | MFCD02113777 |
| Nikkaji Number | J53.078F |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 764.20 °C. @ 760.00 mm Hg (est) |
| Flash Point | 543.00 °F. TCC ( 283.70 °C. ) (est) |
| logP (o/w) | 2.330 (est) |
| Soluble in | water, 8.089 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for norstictic acid usage levels up to | not for fragrance use. |
| Recommendation for norstictic acid flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
bryopogonic acid
1,3-
dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-7H-isobenzofuro(4,5-b)(1,4)benzodioxepin-11-carboxaldehyde
1,3-
dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo07H-isobenzofuro(4,5-b)(1,4)benzodioxepin-11-carboxaldehyde
1,4,10-
trihydroxy-5,8-dimethyl-3,7-dioxo-1,3-dihydro-7H-2,6,12-trioxabenzo[5,6]cyclohepta[1,2-e]indene-11-carbaldehyde
7H-2,6,12-
trioxabenzo[5,6]cyclohept[1,2-e]indene-11-carboxaldehyde, 1,3-dihydro-1,4,10-trihydroxy-5,8-dimethyl-3,7-dioxo-
PubMed:
Norstictic Acid Inhibits Breast Cancer Cell Proliferation, Migration, Invasion, and In Vivo Invasive Growth Through Targeting C-Met.
PubMed:
The Parmotrema acid test: a look at species delineation in the P. perforatum group 40 y later.
PubMed:
Anticancer activities of selected species of North American lichen extracts.
PubMed:
A new depside from Usnea aciculifera growing in Vietnam.
PubMed:
A New Species of Graphis and New Lichen Records from Vietnam, Including a Second Worldwide Report of Sarcographina cyclospora.
PubMed:
Biological activities and chemical composition of lichens from Serbia.
PubMed:
Comparative metabolite profiling and chemical study of Ramalina siliquosa complex using LC-ESI-MS/MS approach.
PubMed:
Biological activities of Toninia candida and Usnea barbata together with their norstictic acid and usnic acid constituents.
PubMed:
Psoromic acid derivatives: a new family of small-molecule pre-mRNA splicing inhibitors discovered by a stage-specific high-throughput in vitro splicing assay.
PubMed:
A new depsidone and antibacterial activities of compounds from Usnea undulata Stirton.
PubMed:
Ionic liquids based microwave-assisted extraction of lichen compounds with quantitative spectrophotodensitometry analysis.
PubMed:
Characterisation of phenols and antioxidant and hypolipidaemic activities of Lethariella cladonioides.
PubMed:
Chemical Composition, Antioxidant, and Antimicrobial Activities of Lichen Umbilicaria cylindrica (L.) Delise (Umbilicariaceae).
PubMed:
Analysis of salazinic, norstictic, and usnic acids in Xanthoparmelia chlorochroa by ultra-performance liquid chromatography/tandem mass spectrometry.
PubMed:
Optimization of a microwave-assisted extraction of secondary metabolites from crustose lichens with quantitative spectrophotodensitometry analysis.
PubMed:
Antimycobacterial activity of lichen substances.
PubMed:
Evaluation of the antimicrobial activity of the acetone extract of the lichen Ramalina farinacea and its (+)-usnic acid, norstictic acid, and protocetraric acid constituents.
PubMed:
Light might regulate divergently depside and depsidone accumulation in the lichen Parmotrema hypotropum by affecting thallus temperature and water potential.
PubMed:
New Record of Karoowia saxeti (Stizenb.) Hale in South Korea.