cosmosiin

apigenin 7-O-beta-dextro-glucopyranoside

CAS: 578-74-5 C21 H20 O10 MW: 432.38240000

Identification

Namecosmosiin
IUPAC5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
CAS Number578-74-5
EINECS209-430-5
FDA UNII7OF2S66PCH
Molecular FormulaC21 H20 O10
Molecular Weight432.38240000
MDL NumberMFCD00016787
Nikkaji NumberJ407.337A
Beilstein065669
XlogP3-0.10 (est)

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 788.93 °C. @ 760.00 mm Hg (est)
Flash Point 537.00 °F. TCC ( 280.70 °C. ) (est)
logP (o/w) -0.040 (est)
Soluble in water, 1417 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for cosmosiin usage levels up tonot for fragrance use.
Recommendation for cosmosiin flavor usage levels up tonot for flavor use.

BOC Sciences

Best of Chemicals Supplier

Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecul...

View All Website 1-631-485-4226 account@bocsci.com

Glentham Life Sciences Ltd

The Chemical, Biochemical & Research Essentials Supplier

Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.

View All Website +44 (0) 1225 667798 info@glentham.com

Potential Uses

None Found

Natural Occurrence

anise seed apple heart wood barley leaf cabocla flower oil brazil Data cacao plant carrot leaf carrot seed chamomile chamomile garden chamomile plant chamomile sweet false chamomile flower chamomile sweet false chamomile plant cosmos bipinnatus flower cumin seed dandelion leaf lemon balm shoot lemon flower lupine white lupine marjoram plant marjoram pollen marjoram shoot olive leaf oregano plant oregano shoot parsley plant peppermint shoot rosemary plant sage thyme plant water mint plant

Synonyms

apigenin 7-O-beta-dextro-glucopyranoside apigenin 7-O-beta-dextro-glucoside apigenin-7-O-glucoside apigenin, 7-b-D-glycopyranoside apigetrin 4H-1- benzopyran-4-one, 7-(β-D-galactopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)- cosmosiine cosmosioside 7-O-.beta.-dextro- glucopyranosyl oxy-4',5-dihydroxyflavone 5- hydroxy-2-(4-hydroxyphenyl)-7-(4,5,6-trihydroxy-3-(hydroxymethyl)(2-oxanyloxy))-4H-chromen-4-one 5- hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one Google Patents: Flavor composition containing flavone glycosides PubMed: Leaf Extract of Markhamia platycalyx: Polyphenolic Profile, Acute Toxicity, Anti-inflammatory, Hepatoprotective and in vitro Antioxidant Activities. PubMed: Simultaneous determination of 13 chemical marker compounds in Gwakhyangjeonggi-san, a herbal formula, with validated analytical methods. PubMed: Identification and quantification of leaf surface flavonoids in wild-growing populations of Dracocephalum kotschyi by LC-DAD-ESI-MS. PubMed: Cytotoxic constituents from the leaves of Broussonetia papyrifera. PubMed: Phytochemical composition and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. ex Schult. Stem (Amaranthaceae). PubMed: Polyphenolic profile and biological activity of Salvia splendens leaves. PubMed: [Simultaneous determination of 6 active components in Chrysanthemum morifolium by HPLC]. PubMed: Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system. PubMed: Flavonoid composition of Juniperus oblonga Bieb. PubMed: Proteomic study of granulocytic differentiation induced by apigenin 7-glucoside in human promyelocytic leukemia HL-60 cells. PubMed: Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé. PubMed: Generation of stable reporter breast cancer cell lines for the identification of ER subtype selective ligands. PubMed: Phenolic chemical composition of Petroselinum crispum extract and its effect on haemostasis. PubMed: LC determination of luteolin-7-O-β-D-glucoside and apigenin-7-O-β-D-glucoside in rat plasma after administration of Humulus scandens extract and its application to pharmacokinetic studies. PubMed: High-performance liquid chromatographic determination and pharmacokinetic study of apigenin-7-O-β-D-glucoside in rat plasma after intravenous administration. PubMed: Apigetrin induces erythroid differentiation of human leukemia cells K562: proteomics approach. PubMed: Hexaconazole induces antioxidant protection and apigenin-7-glucoside accumulation in Matricaria chamomilla plants subjected to drought stress. PubMed: A fluorescence resonance energy transfer-based fluorometer assay for screening anti-coxsackievirus B3 compounds. PubMed: Secondary metabolites of Hypericum confertum and their possible chemotaxonomic significance. PubMed: [Study on the flavonoids constituents of Trachelospermum jasminoides]. PubMed: Insulin-Mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells. PubMed: Mesophyll distribution of 'antioxidant' flavonoid glycosides in Ligustrum vulgare leaves under contrasting sunlight irradiance. PubMed: New bioactive compounds from Aloe hijazensis. PubMed: The bioavailability of apigenin-7-glucoside is influenced by human intestinal microbiota in rats. PubMed: [Studies on chemical constituents from Pteris multifida]. PubMed: Chemical constituents from the seeds of Trifolium alexandrinum. PubMed: Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach. PubMed: [Studies on chemical constituents in Huangjuhua (flowers of Chrysanthemum morifolium)]. PubMed: Chemical constituents from the leaves of Broussonetia papyrifera. PubMed: Antioxidative activity of the flower of Torenia fournieri. PubMed: [Chemical study on aerial parts of Ligusticum chuanxiong]. PubMed: Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells. PubMed: [Stduy on flavonoids in Ligustrum lucidum]. PubMed: Achillea millefolium L. s.l. -- is the anti-inflammatory activity mediated by protease inhibition? PubMed: Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt. PubMed: [Studies on flavones in of Lavandula augustifolia]. PubMed: [Studies on chemical constituents of Acroptilon repens]. PubMed: [Determination of main flavone glycosides in Flos Chrysanthemi and observation of factors influenced contents]. PubMed: Superheated liquid extraction of oleuropein and related biophenols from olive leaves. PubMed: Structural studies of zoospore attractants from Trachelospermum jasminoides var. pubescens: taxifolin 3-O-glycosides. PubMed: Effects of compounds in leaves of Salix matsudana on arachidonic acid metabolism. PubMed: Mechanisms of apigenin-7-glucoside as a hepatoprotective agent. PubMed: Antioxidant and immunomodulatory constituents of henna leaves. PubMed: [Studies on the flavonoids in herb from Scutellaria barbata]. PubMed: Supercritical carbon dioxide extraction of chamomile flowers: extraction efficiency, stability, and in-line inclusion of chamomile-carbon dioxide extract in beta-cyclodextrin. PubMed: Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice. PubMed: Antioxidative glycosides from the leaves of Ligustrum robustum. PubMed: [Studies on the chemical constituents from Chrysanthemum morifolium Ramat]. PubMed: Calmodulin inhibitors from Leucophyllum ambiguum. PubMed: [Isolation of resisting thrombus and arteriosclerosis compounds in leaves of Salix matsudana]. PubMed: [Studies on chemical constituents of leaves of Salix matsudana Koidz and their influence on lipolysis]. PubMed: Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model. PubMed: Effect of six flavonoid compounds from Ixeris sonchifolia on stimulus-induced superoxide generation and tyrosyl phosphorylation in human neutrophils. PubMed: Inhibitory effect of luteolin 4'-O-glucoside from Kummerowia striata and other flavonoids on interleukin-5 bioactivity. PubMed: Flavonoids from Aquilegia vulgaris L. Part II. Derivatives of apigenin and luteolin. PubMed: [Separation and identification of the flavonoids from Buddleia officinalis Maxim]. PubMed: In vivo skin penetration studies of camomile flavones. PubMed: [Absorption and excretion of apigenin, apigenin-7-glycoside and herniarin after oral administration of extracts of Matricaria recutita (L.) (syn. Chamomilla recutita (L.) Rauschert)]. PubMed: Skin anti-inflammatory activity of apigenin-7-glucoside in rats. PubMed: [Chemical constituents of the flower of Ligustrum lucidum Ait]. PubMed: Bioflavonoid effects on in vitro cultures of Plasmodium falciparum. Inhibition of permeation pathways induced in the host cell membrane by the intraerythrocytic parasite. PubMed: Fast atom bombardment and tandem mass spectrometry for structure determination of steroid and flavonoid glycosides. PubMed: Transacylation in the flavonoid series. I. A new synthesis of cosmosiin and tilianin.