pedunculagin
Identification
| Name | pedunculagin |
| CAS Number | 7045-42-3 |
| FDA UNII | 1KN18B7Y0X |
| Molecular Formula | C34 H24 O22 |
| Molecular Weight | 784.54768000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 1556.94 °C. @ 760.00 mm Hg (est) |
| Flash Point | 898.00 °F. TCC ( 481.10 °C. ) (est) |
| logP (o/w) | 1.293 (est) |
| Soluble in | water, 10.1 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for pedunculagin usage levels up to | not for fragrance use. |
| Recommendation for pedunculagin flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
pedunculagin
PubMed:
Size and molecular flexibility affect the binding of ellagitannins to bovine serum albumin.
PubMed:
Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS.
PubMed:
Inhibition of matrix metalloproteinase-1 and type-I procollagen expression by phenolic compounds isolated from the leaves of Quercus mongolica in ultraviolet-irradiated human fibroblast cells.
PubMed:
Walnuts have potential for cancer prevention and treatment in mice.
PubMed:
Evaluation of Phyllanthus emblica extract on cold pressor induced cardiovascular changes in healthy human subjects.
PubMed:
Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus: a randomized, double-blind, controlled study.
PubMed:
Phenolic constituents from Alchemilla vulgaris L. and Alchemilla mollis (Buser) Rothm. at different dates of harvest.
PubMed:
An overview on antidiabetic medicinal plants having insulin mimetic property.
PubMed:
Phenolic constituents from Alchemilla vulgaris L. and Alchemilla mollis (Buser) Rothm. at different dates of harvest.
PubMed:
Antioxidant activity of isolated ellagitannins from red raspberries and cloudberries.
PubMed:
Glutinoin, a novel antioxidative ellagitannin from Alnus glutinosa cones with glutinoic acid dilactone moiety.
PubMed:
Simple solution for a complex problem: proanthocyanidins, galloyl glucoses and ellagitannins fit on a single calibration curve in high performance-gel permeation chromatography.
PubMed:
Identification and quantification of phenolic compounds from pomegranate (Punica granatum L.) peel, mesocarp, aril and differently produced juices by HPLC-DAD-ESI/MS(n).
PubMed:
ent-Eudesmane sesquiterpenoids, galloyl esters of the oak lactone precursor, and a 3-O-methylellagic acid glycoside from the wood of Platycarya strobilacea.
PubMed:
Effect of pedunculagin investigated by non-invasive evaluation on atopic-like dermatitis in NC/Nga mice.
PubMed:
Development of chromatographic methods for determination of agrimoniin and related polyphenols in pharmaceutical products.
PubMed:
Euscaphinin, a new ellagitannin dimer from Euscaphis japonica (THUNB.) KANITZ.
PubMed:
Fatty acid synthase inhibitors from Geum japonicum Thunb. var. chinense.
PubMed:
Ellagitannin composition of blackberry as determined by HPLC-ESI-MS and MALDI-TOF-MS.
PubMed:
[Studies on hydrolysable tannin constituents in seed of Juglans regia(I)].
PubMed:
Anticancer and antioxidant tannins from Pimenta dioica leaves.
PubMed:
Tannin composition affects the oxidative activities of tree leaves.
PubMed:
Plant phenolics inhibit neutrophil elastase.
PubMed:
Purification and biochemical characterization of a fibroblast growth factor-binding protein (FGF-BP) from the lactoferrin fraction of bovine milk.
PubMed:
Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign.
PubMed:
Effects of sample drying and storage, and choice of extraction solvent and analysis method on the yield of birch leaf hydrolyzable tannins.
PubMed:
Effect of tannins from Quercus suber and Quercus coccifera leaves on ethanol-induced gastric lesions in mice.
PubMed:
Effect of Emblica officinalis tannoids on a rat model of tardive dyskinesia.
PubMed:
Antioxidant activity of tannoid principles of Emblica officinalis (amla) in chronic stress induced changes in rat brain.
PubMed:
Further characterization of galloyl pedunculagin as an effective autophosphorylation inhibitor of C-kinase in vitro.
PubMed:
Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography--electrospray ionisation mass spectrometry.
PubMed:
Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
PubMed:
Seasonal variation in the content of hydrolysable tannins in leaves of Betula pubescens.
PubMed:
Characterization of the polyphenolic composition of purple loosestrife (Lythrum salicaria).
PubMed:
Biochemical characterization of galloyl pedunculagin (ellagitannin) as a selective inhibitor of the beta-regulatory subunit of A-kinase in vitro.
PubMed:
Effect of bioactive tannoid principles of Emblica officinalis on iron-induced hepatic toxicity in rats.
PubMed:
Antioxidant activity of active tannoid principles of Emblica officinalis (amla).
PubMed:
Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade.
PubMed:
Synthesis of Trideca-O-methyl-alpha-pedunculagin. Diastereo-Favoritism Studies on Intramolecular Ester-Cyclization of Axially Chiral Diphenic Acids with Carbohydrate Core.
PubMed:
Ellagitannin Chemistry. First Total Synthesis of the 2,3- and 4,6-Coupled Ellagitannin Pedunculagin.
PubMed:
Phenolic compounds from Duchesnea chrysantha and their cytotoxic activities in human cancer cell.
PubMed:
Ellagitannins and complex tannins from Quercus petraea bark.
PubMed:
Carbonic anhydrase inhibitors from the pericarps of Punica granatum L.
PubMed:
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
PubMed:
In vitro screening of antimotility effect on human sperm with polyphenolic compounds purified from Chinese herbal medicines.
PubMed:
Enzymatic sulfation of polyphenols related to tannins by arylsulfotransferase.