salvianolic acid B
(2R-(2alpha,3beta(R*),4(E(R*))))-3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofura
Identification
| Name | salvianolic acid B |
| CAS Number | 115939-25-8 |
| FDA UNII | C1GQ844199 |
| Molecular Formula | C36 H30 O16 |
| Molecular Weight | 718.62230000 |
Regulatory
Physical Properties
| Appearance | yellow-brown powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 1020.27 °C. @ 760.00 mm Hg (est) |
| Flash Point | 612.00 °F. TCC ( 322.10 °C. ) (est) |
| logP (o/w) | 2.140 (est) |
| Soluble in | water, 1.04 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for salvianolic acid B usage levels up to | not for fragrance use. |
| Recommendation for salvianolic acid B flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
(2R-(2alpha,3beta(R*),4(E(R*))))-3-(1-
carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofura
salvianolicacid B
PubMed:
Transformation of salvianolic acid B to salvianolic acid a in aqueous solution and the in vitro liver protective effect of the main products.
PubMed:
Effects of Danshensu and Salvianolic Acid B from Salvia miltiorrhiza Bunge (Lamiaceae) on cell proliferation and collagen and melanin production.
PubMed:
Comparison of the inhibitory effect against copper ion-induced oxidation in rat plasma after oral administration of salvianolic acid B and its decocted solutions.
PubMed:
[Study on chemical changes of salvianolic acid B and lithospermic acid aqueous under conditions of high temperature and high pressure].
PubMed:
Chemical conversions of salvianolic acid B by decoction in aqueous solution.
PubMed:
Salvianolic acid B inhibits low-density lipoprotein oxidation and neointimal hyperplasia in endothelium-denuded hypercholesterolaemic rabbits.
PubMed:
Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B.
PubMed:
Dan-Qi prescription ameliorate insulin resistance through overall corrective regulation of glucose and fat metabolism.
PubMed:
Comparative pharmacokinetic and tissue distribution profiles of four major bioactive components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe.
PubMed:
The profiling of bioactive ingredients of differently aged Salvia miltiorrhiza roots.
PubMed:
Antioxidant activities of leaf extract of Salvia miltiorrhiza Bunge and related phenolic constituents.
PubMed:
A pair of new antioxidant phenolic acid stereoisomers isolated from danshen injection (lyophilized powder).
PubMed:
Nematicidal activity of mint aqueous extracts against the root-knot nematode Meloidogyne incognita.
PubMed:
The stability investigation of compound Danshen injection (a traditional medicine) with a new high-performance liquid chromatography method.
PubMed:
Characterisation of phenolic antioxidants in aqueous extract of Orthosiphon grandiflorus tea by LC-ESI-MS/MS coupled to DPPH assay.
PubMed:
The Arabidopsis PAP1 transcription factor plays an important role in the enrichment of phenolic acids in Salvia miltiorrhiza.
PubMed:
Genetic stability, active constituent, and pharmacoactivity of Salvia miltiorrhiza hairy roots and wild plant.
PubMed:
Chemical characteristics of Salvia miltiorrhiza (Danshen) collected from different locations in China.
PubMed:
[Absorption and isolation of macroporous resin for five salvianolic acids from Salviae mitiorrhizae].
PubMed:
Separation and identification of water-soluble salvianolic acids from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography and ESI-MS analysis.
PubMed:
Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress.