angustifoline
1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, decahydro-4-(2-propenyl)-, (1S-(1a,4a,5a,11aa))-
Identification
| Name | angustifoline |
| IUPAC | (1R,2R,9R,10S)-10-allyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one |
| CAS Number | 550-43-6 |
| FDA UNII | Search |
| Molecular Formula | C14 H22 N2 O |
| Molecular Weight | 234.34254000 |
Regulatory
Physical Properties
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Boiling Point | 377.00 to 378.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 360.00 °F. TCC ( 182.10 °C. ) (est) |
| logP (o/w) | 2.294 (est) |
| Soluble in | water, 410.5 mg/L @ 25 °C (est) |
No sensory data available
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | natural substances and extractives |
| Recommendation for angustifoline usage levels up to | not for fragrance use. |
| Recommendation for angustifoline flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
(1R,2R,9R,10S)-10-
allyl-7,11-diazatricyclo[7.3.1.02,7]tridecan-6-one
(1S-(1alpha,4alpha,5alpha,11aalpha))-
decahydro-4-(2-propenyl)-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one
1,5-
methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, decahydro-4-(2-propenyl)-, (1S-(1a,4a,5a,11aa))-
1,5-
methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, decahydro-4-(2-propenyl)-, (1S-(1alpha,4alpha,5alpha,11aalpha))-
PubMed:
Determination of quinolizidine alkaloids in different Lupinus species by NACE using UV and MS detection.
PubMed:
Quinolizidine alkaloids in seeds of lupin genotypes of different origins.
PubMed:
Quinolizidine alkaloids and phomopsins in lupin seeds and lupin containing food.
PubMed:
Alkaloid profile of leaves and seeds of Lupinus hintonii C. P. Smith.
PubMed:
Biochemical and partial molecular characterization of bitter and sweet forms of Lupinus angustifolius, an experimental model for study of molecular regulation of quinolizidine alkaloid biosynthesis.
PubMed:
A 90-day feeding study of the alkaloids of Lupinus angustifolius in the rat.
PubMed:
(+)-Angustifoline: A Minor Alkaloid from Lupinus albus1.
PubMed:
N-Methylation of quinolizidine alkaloids: an S-adenosyl-L-methionine: cytisine N-methyltransferase from Laburnum anagyroides plants and cell cultures of L. alpinum and Cytisus canariensis.