S-allyl-laevo-cysteine

S- allyl cysteine S- allyl L-cysteine allyl laevo-cysteine (2R)-3-( allyl thio)-2-aminopropanoic acid S- allyl-L-cysteine S- allylcysteine (2R)-2- amino-3-(prop-2-en-1-yl sulfanyl) propanoic acid (2R)-2- amino-3-prop-2-enylsulfanylpropanoic acid cysteine, S-2-propen-1-yl- L- cysteine,S-2-propen-1-yl- L- deoxyalliin S- prop-2-en-1-ylcysteine S-2- propenyl-L-cysteine S-2- propenyl-laevo-cysteine PubMed: Oral Administration of (S)-Allyl-l-Cysteine and Aged Garlic Extract to Rats: Determination of Metabolites and Their Pharmacokinetics. PubMed: EGFR gene regulation in colorectal cancer cells by garlic phytocompounds with special emphasis on S-Allyl-L-Cysteine Sulfoxide. PubMed: Thermolysis kinetics and thermal degradation compounds of alliin. PubMed: Evaluation of the Effects of S-Allyl-L-cysteine, S-Methyl-L-cysteine, trans-S-1-Propenyl-L-cysteine, and Their N-Acetylated and S-Oxidized Metabolites on Human CYP Activities. PubMed: Alliin Attenuated RANKL-Induced Osteoclastogenesis by Scavenging Reactive Oxygen Species through Inhibiting Nox1. PubMed: Molecular detection and in vitro antioxidant activity of S-allyl-L-cysteine (SAC) extracted from Allium sativum. PubMed: Taste-Active Maillard Reaction Products in Roasted Garlic (Allium sativum). PubMed: Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration. PubMed: PMK-S005 Alleviates Age-Related Gastric Acid Secretion, Inflammation, and Oxidative Status in the Rat Stomach. PubMed: Neuroprotective effect of S-allyl-l-cysteine derivatives against endoplasmic reticulum stress-induced cytotoxicity is independent of calpain inhibition. PubMed: Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel. PubMed: Pharmacokinetics of S-Allyl-l-cysteine in Rats Is Characterized by High Oral Absorption and Extensive Renal Reabsorption. PubMed: S-allyl-L-cysteine and isoliquiritigenin improve mitochondrial function in cellular models of oxidative and nitrosative stress. PubMed: Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats. PubMed: Identification of a flavin-containing S-oxygenating monooxygenase involved in alliin biosynthesis in garlic. PubMed: Enzymatic synthesis of γ-L-glutamyl-S-allyl-L-cysteine, a naturally occurring organosulfur compound from garlic, by Bacillus licheniformis γ-glutamyltranspeptidase. PubMed: Effective production of S-allyl-L-cysteine through a homogeneous reaction with activated endogenous γ-glutamyltranspeptidase in garlic (Allium Sativum). PubMed: Metabolism, excretion, and pharmacokinetics of S-allyl-L-cysteine in rats and dogs. PubMed: Garlic γ-glutamyl transpeptidases that catalyze deglutamylation of biosynthetic intermediate of alliin. PubMed: Protective effects of garlic extract, PMK-S005, against nonsteroidal anti-inflammatory drugs-induced acute gastric damage in rats. PubMed: S-allyl L-cysteine protects the retina against kainate excitotoxicity in the rat. PubMed: Development and validation of S-allyl-L-cysteine in rat plasma using a mixed-mode reversed-phase and cation-exchange LC-ESI-MS/MS method: application to pharmacokinetic studies. PubMed: Protective effect of S-allyl-L-cysteine against endoplasmic reticulum stress-induced neuronal death is mediated by inhibition of calpain. PubMed: Retraction. S-Allyl-L-cysteine sulfoxide inhibits tumor necrosis factor-alpha induced monocyte adhesion and intercellular cell adhesion molecule-1 expression in human umbilical vein endothelial cells. PubMed: Effect of processing and storage time on the contents of organosulfur compounds in pickled blanched garlic. PubMed: Effects of SAC on oxidative stress and NO availability in placenta: potential benefits to preeclampsia. PubMed: The effects and underlying mechanisms of S-allyl l-cysteine treatment of the retina after ischemia/reperfusion. PubMed: Alliinase from Ensifer adhaerens and Its Use for Generation of Fungicidal Activity. PubMed: The "aged garlic extract:" (AGE) and one of its active ingredients S-allyl-L-cysteine (SAC) as potential preventive and therapeutic agents for Alzheimer's disease (AD). PubMed: [Effect of S-allyl-L-cysteine on isolate heart subject to ischemia/reperfusion]. PubMed: Effects of s-allyl-L-cysteine on cell proliferation and neuroblast differentiation in the mouse dentate gyrus. PubMed: Oxidative insults to neurons and synapse are prevented by aged garlic extract and S-allyl-L-cysteine treatment in the neuronal culture and APP-Tg mouse model. PubMed: Palladium(II) complex with S-allyl-L-cysteine: new solid-state NMR spectroscopic measurements, molecular modeling and antibacterial assays. PubMed: Garlic flavonoids and organosulfur compounds: impact on the hepatic pharmacokinetics of saquinavir and darunavir. PubMed: 3-(allyltrisulfanyl)-2-aminopropanoic acid, a novel nonvolatile water-soluble antimicrobial sulfur compound in heated garlic. PubMed: S-allyl-L-cysteine sulfoxide inhibits tumor necrosis factor-alpha induced monocyte adhesion and intercellular cell adhesion molecule-1 expression in human umbilical vein endothelial cells. PubMed: Protective effects of cysteine analogues on acute myocardial ischemia: novel modulators of endogenous H(2)S production. PubMed: S-allyl L-cysteine diminishes cerebral ischemia-induced mitochondrial dysfunctions in hippocampus. PubMed: Purification and characterization of flavin-containing monooxygenase isoform 3 from rat kidney microsomes. PubMed: Unusual cystine lyase activity of the enzyme alliinase: direct formation of polysulphides. PubMed: Anti-amyloidogenic activity of S-allyl-L-cysteine and its activity to destabilize Alzheimer's beta-amyloid fibrils in vitro. PubMed: Amyloid beta-protein potentiates tunicamycin-induced neuronal death in organotypic hippocampal slice cultures. PubMed: Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods. PubMed: Two structures of alliinase from Alliium sativum L.: apo form and ternary complex with aminoacrylate reaction intermediate covalently bound to the PLP cofactor. PubMed: S-Allyl-L-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase. PubMed: Structure-activity relationship of neuroprotective and reactive oxygen species scavenging activities for allium organosulfur compounds. PubMed: Dietary S-allyl-L-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in stroke-prone spontaneously hypertensive rats. PubMed: Changes in organosulfur compounds in garlic cloves during storage. PubMed: N-acetylcysteine selectively protects cerebellar granule cells from 4-hydroxynonenal-induced cell death. PubMed: Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons. PubMed: Redox-sensitive proteins are potential targets of garlic-derived mercaptocysteine derivatives. PubMed: In vitro interactions of water-soluble garlic components with human cytochromes p450. PubMed: Aged garlic extract and its constituents inhibit platelet aggregation through multiple mechanisms. PubMed: 1H-15N NMR studies of the complex bis(S-allyl-L-cysteinate)palladium(II). PubMed: Model studies on precursor system generating blue pigment in onion and garlic. PubMed: Aminotransferase, L-amino acid oxidase and beta-lyase reactions involving L-cysteine S-conjugates found in allium extracts. Relevance to biological activity? PubMed: Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery. PubMed: S-allyl-L-cysteine selectively protects cultured rat hippocampal neurons from amyloid beta-protein- and tunicamycin-induced neuronal death. PubMed: Neurotoxicity induced by amyloid beta-peptide and ibotenic acid in organotypic hippocampal cultures: protection by S-allyl-L-cysteine, a garlic compound. PubMed: Protective effect of S-allyl-L-cysteine, a garlic compound, on amyloid beta-protein-induced cell death in nerve growth factor-differentiated PC12 cells. PubMed: High-performance ion-pair chromatography method for simultaneous analysis of alliin, deoxyalliin, allicin and dipeptide precursors in garlic products using multiple mass spectrometry and UV detection. PubMed: Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases. PubMed: Biomonitoring the intake of garlic via urinary excretion of allyl mercapturic acid. PubMed: N alpha-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound identified in aged garlic extract. PubMed: Methionine S-oxidation in human and rabbit liver microsomes: evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3. PubMed: Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, and noradrenaline and adrenaline secretion in rats. PubMed: Species and sex differences in expression of flavin-containing monooxygenase form 3 in liver and kidney microsomes. PubMed: The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins. PubMed: Neurotrophic activity of organosulfur compounds having a thioallyl group on cultured rat hippocampal neurons. PubMed: Cysteine-S-conjugate beta-lyase activity and pyridoxal phosphate binding site of onion alliin lyase. PubMed: Oxidation of cysteine S-conjugates by rabbit liver microsomes and cDNA-expressed flavin-containing mono-oxygenases: studies with S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2,2-trichlorovinyl)-L-cysteine, S-allyl-L-cysteine, and S-benzyl-L-cysteine. PubMed: New agents for cancer chemoprevention. PubMed: Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers. PubMed: On the Isolation and Characterization of a C-S-Lyase Preparation from Leek,Allium porrum. PubMed: A novel amino acid glycoside and three amino acids from Allium sativum. PubMed: Interspecific hybrid between Allium cepa and Allium sativum. PubMed: The acute effects of S-(1,2-dichlorovinyl)-L-cysteine and related chemicals on renal function and ultrastructure in the pentobarbital-anesthetized dog: structure-activity relationships, biotransformation, and unique site-specific nephrotoxicity. PubMed: HPLC of S-Alk(en)yl-L-cysteine Derivatives in Garlic including Quantitative Determination of (+)-S-Allyl-L-cysteine Sulfoxide (Alliin). PubMed: Studies on the antimutagenic activities of garlic extract. PubMed: The C-S lyases of higher plants: preparation and properties of homogeneous alliin lyase from garlic (Allium sativum). PubMed: Biosynthesis of mercapturic acids from allyl alcohol, allyl esters and acrolein. PubMed: Purification of the alliin lyase of garlic, Allium sativum L. PubMed: gama-L-Glutamyl-S-allyl-L-cysteine, a new gama-glutamyl peptide in garlic.