2,4,5-trihydroxybutyrophenone

1-butanone, 1-(2,4,5-trihydroxyphenyl)-

CAS: 1421-63-2 C10 H12 O4 MW: 196.20244000

Identification

Name2,4,5-trihydroxybutyrophenone
IUPAC1-(2,4,5-trihydroxyphenyl)butan-1-one
CAS Number1421-63-2
EINECS215-824-8
FDA UNIIKN729W3LR0
Molecular FormulaC10 H12 O4
Molecular Weight196.20244000
MDL NumberMFCD00020019
Nikkaji NumberJ40.577I
Beilstein2577028

Regulatory

FDA Mainterm (SATF)1421-63-2 ; 2,4,5-TRIHYDROXYBUTYROPHENONE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance yellow tan crystalline powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 149.00 to 153.00 °C. @ 760.00 mm Hg
Boiling Point 409.00 to 410.00 °C. @ 760.00 mm Hg (est)
Flash Point 420.00 °F. TCC ( 215.40 °C. ) (est)
logP (o/w) 1.872 (est)
Soluble in water, 3459 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral Toxicityintraperitoneal-mouse LD50 200 mg/kg
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryantioxidants
Recommendation for 2,4,5-trihydroxybutyrophenone usage levels up tonot for fragrance use.
Recommendation for 2,4,5-trihydroxybutyrophenone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

1- butanone, 1- (2,4,5-trihydroxyphenyl)- 1- butanone, 1-(2,4,5-trihydroxyphenyl)- butyrophenone, 2',4',5'-trihydroxy- THBP 2',4',5'- trihydroxybutyrophenone 1-(2,4,5- trihydroxyphenyl)-1-butanone 1-(2,4,5- trihydroxyphenyl)butan-1-one PubMed: Fast analysis of synthetic antioxidants in edible vegetable oil using trilinear component modeling of liquid chromatography-diode array detection data. PubMed: Characterization of phloretin-sensitive urea export from the perfused rat liver. PubMed: Liquid chromatographic method for the determination of nine phenolic antioxidants in butter oil: collaborative study. PubMed: Esters of 3,4-dihydroxybenzoic acid, highly effective inhibitors of the sn-glycerol-3-phosphate oxidase of Trypanosoma brucei brucei. PubMed: High performance liquid chromatographic determination of seven antioxidants in oil and lard: collaborative study. PubMed: Systematic identification of antioxidants in lards, shortenings, and vegetable oils by thin layer chromatography. PubMed: High performance liquid chromatographic determination of nine phenolic antioxidants in oils, lards, and shortenings. PubMed: A rapid gas-liquid chromatographic method for the multi-determination of antioxidants in fats, oils and dried food products.