hesperetin

abdoliance (Givaudan) 4H-1- benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (2S)- 4H-1- benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-, (S)- (S)-2,3- dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone (S)-2,3- dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one 5,7- dihydroxy-2-(3-hydroxy-4-methoxy-phenyl)-chroman-4-one (2S)-5,7- dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-chromen-4-one (2S)-5,7- dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chroman-4-one flavanone, 3',5,7-trihydroxy-4'-methoxy- hesperetin natural hesperitin P.E 4'- methoxy-3',5,7-trihydroxyflavanone (±)-3',5,7- trihydroxy-4'-methoxyflavanone 3',5,7- trihydroxy-4'-methoxyflavanone 5,7,3'- trihydroxy-4'-methoxyflavanone 3',5,7- trihydroxy-4-methoxyflavanone PubMed: Encapsulation and micronization effectively improve orange beverage flavanones bioavailability in humans. PubMed: Evaluation of bioactive components and antioxidant and anticancer properties of citrus wastes generated during bioethanol production. PubMed: Effects of antioxidants of bamboo leaves and flavonoids on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) formation in chemical model systems. PubMed: Absorption, metabolism, and excretion of fermented orange juice (poly)phenols in rats. PubMed: Hydrolysis of flavanone glycosides by β-glucosidase from Pyrococcus furiosus and its application to the production of flavanone aglycones from citrus extracts. PubMed: Characterisation of honeys according to their content of phenolic compounds using high performance liquid chromatography/tandem mass spectrometry. PubMed: Citrus flavanones enhance carotenoid uptake by intestinal Caco-2 cells. PubMed: Hesperetin Stimulates Cholecystokinin Secretion in Enteroendocrine STC-1 Cells. PubMed: Fermented orange juice: source of higher carotenoid and flavanone contents. PubMed: Suitability of antioxidant capacity, flavonoids and phenolic acids for floral authentication of honey. Impact of industrial thermal treatment. PubMed: Hesperidin metabolite hesperetin-7-O-glucuronide, but not hesperetin-3'-O-glucuronide, exerts hypotensive, vasodilatory, and anti-inflammatory activities. PubMed: Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions. PubMed: Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. PubMed: Bioavailability of dietary (poly)phenols: a study with ileostomists to discriminate between absorption in small and large intestine. PubMed: Quantification of hesperidin in citrus-based foods using a fungal diglycosidase. PubMed: Prunin- and hesperetin glucoside-alkyl (C4-C18) esters interaction with Jurkat cells plasma membrane: consequences on membrane physical properties and antioxidant capacity. PubMed: A comparison study on the binding of hesperetin and luteolin to bovine serum albumin by spectroscopy. PubMed: Assessment of phytochemical content in human milk during different stages of lactation. PubMed: Antioxidant and hepatoprotective effects of Schisandra chinensis pollen extract on CCl4-induced acute liver damage in mice. PubMed: Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions. PubMed: Identification of flavonoids with trypsin inhibitory activity extracted from orange peel and green tea leaves. PubMed: Composition of native Australian herbs polyphenolic-rich fractions and in vitro inhibitory activities against key enzymes relevant to metabolic syndrome. PubMed: Empirical, thermodynamic and quantum-chemical investigations of inclusion complexation between flavanones and (2-hydroxypropyl)-cyclodextrins. PubMed: Iron reduction potentiates hydroxyl radical formation only in flavonols. PubMed: Enzymatic bioconversion of citrus hesperidin by Aspergillus sojae naringinase: enhanced solubility of hesperetin-7-O-glucoside with in vitro inhibition of human intestinal maltase, HMG-CoA reductase, and growth of Helicobacter pylori. PubMed: Protective effects of sweet orange (Citrus sinensis) peel and their bioactive compounds on oxidative stress. PubMed: Evaluation of matrix effect in determination of some bioflavonoids in food samples by LC-MS/MS method. PubMed: The apoptotic effect of hesperetin on human cervical cancer cells is mediated through cell cycle arrest, death receptor, and mitochondrial pathways. PubMed: Rapid assessment of endpoint antioxidant capacity of red wines through microchemical methods using a kinetic matching approach. PubMed: Pro-cellular survival and neuroprotection of citrus flavonoid: the actions of hesperetin in PC12 cells. PubMed: Phytonutrient intake by adults in the United States in relation to fruit and vegetable consumption. PubMed: In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as a novel antiangiogenesis agent. PubMed: Differential effects of flavonoids on barrier integrity in human intestinal Caco-2 cells. PubMed: Study on the interference of rat feed to pharmacokinetics of flavonoids. PubMed: Anti-aging effects of hesperidin on Saccharomyces cerevisiae via inhibition of reactive oxygen species and UTH1 gene expression. PubMed: Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads. PubMed: Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy. PubMed: Bioavailability of orally administered water-dispersible hesperetin and its effect on peripheral vasodilatation in human subjects: implication of endothelial functions of plasma conjugated metabolites. PubMed: Melanogenesis of murine melanoma cells induced by hesperetin, a Citrus hydrolysate-derived flavonoid. PubMed: Neuroprotective effects of citrus flavonoids. PubMed: Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes. PubMed: Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line--a comparative study. PubMed: Antioxidant and anti-inflammatory potential of hesperetin metabolites obtained from hesperetin-administered rat serum: an ex vivo approach. PubMed: Phytonutrient Intake by Adults in the United States in Relation to Fruit and Vegetable Consumption. PubMed: Beneficial effect of hesperetin on cadmium induced oxidative stress in rats: an in vivo and in vitro study. PubMed: Flavonoids in tropical citrus species. PubMed: Binding of citrus flavanones and their glucuronides and chalcones to human serum albumin. PubMed: Kaempferol inhibits enterovirus 71 replication and internal ribosome entry site (IRES) activity through FUBP and HNRP proteins. PubMed: Antioxidant capacities and total phenolic contents increase with gamma irradiation in two types of Malaysian honey. PubMed: Evaluation of antioxidant and inhibitory activities for different subclasses flavonoids on enzymes for rheumatoid arthritis. PubMed: Effect of hesperetin against oxidative stress via ER- and TrkA-mediated actions in PC12 cells. PubMed: Molecular structures of citrus flavonoids determine their effects on lipid metabolism in HepG2 cells by primarily suppressing apoB secretion. PubMed: Hesperetin protects testicular toxicity of doxorubicin in rat: role of NFκB, p38 and caspase-3. PubMed: Free fruit at workplace intervention increases total fruit intake: a validation study using 24 h dietary recall and urinary flavonoid excretion. PubMed: Chemical synthesis of citrus flavanone glucuronides. PubMed: Comparison of hesperetin and its metabolites for cholesterol-lowering and antioxidative efficacy in hypercholesterolemic hamsters. PubMed: Effects of hesperetin on the production of inflammatory mediators in IL-1beta treated human synovial cells. PubMed: Stereoselective conjugation, transport and bioactivity of s- and R-hesperetin enantiomers in vitro. PubMed: Concentration and solubility of flavanones in orange beverages affect their bioavailability in humans. PubMed: Enzyme technology for precision functional food ingredient processes. PubMed: Relative bioavailability of the flavonoids quercetin, hesperetin and naringenin given simultaneously through diet. PubMed: The effect of co-administered flavonoids on the metabolism of hesperetin and the disposition of its metabolites in Caco-2 cell monolayers. PubMed: Absorption, conjugation and excretion of the flavanones, naringenin and hesperetin from alpha-rhamnosidase-treated orange juice in human subjects. PubMed: Identification of metabolites in human plasma and urine after consumption of a polyphenol-rich juice drink. PubMed: Identification of bisprenylated benzoic acid derivatives from yerba santa (Eriodictyon ssp.) using sensory-guided fractionation. PubMed: Characterization of flavor modulating effects in complex mixtures via high temperature liquid chromatography. PubMed: Molecular mechanism of hesperetin-7-O-glucuronide, the main circulating metabolite of hesperidin, involved in osteoblast differentiation. PubMed: Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance rates. PubMed: Major phytochemical composition of 3 native Korean citrus varieties and bioactive activity on V79-4 cells induced by oxidative stress. PubMed: Efficacy of the potential chemopreventive agent, hesperetin (citrus flavanone), on 1,2-dimethylhydrazine induced colon carcinogenesis. PubMed: Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf. PubMed: The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. PubMed: Yoghurt impacts on the excretion of phenolic acids derived from colonic breakdown of orange juice flavanones in humans. PubMed: Modulation of Akt, JNK, and p38 activation is involved in citrus flavonoid-mediated cytoprotection of PC12 cells challenged by hydrogen peroxide. PubMed: Mangiferin and hesperidin metabolites are absorbed from the gastrointestinal tract of pigs after oral ingestion of a Cyclopia genistoides (honeybush tea) extract. PubMed: Bioavailability and metabolism of orange juice flavanones in humans: impact of a full-fat yogurt. PubMed: Naringenin and hesperetin induce growth arrest, apoptosis, and cytoplasmic fat deposit in human preadipocytes. PubMed: Sodium borohydride/chloranil-based assay for quantifying total flavonoids. PubMed: Absorption, metabolism and excretion of flavanones from single portions of orange fruit and juice and effects of anthropometric variables and contraceptive pill use on flavanone excretion. PubMed: Biotransformation of ginsenoside Rb1, crocin, amygdalin, geniposide, puerarin, ginsenoside Re, hesperidin, poncirin, glycyrrhizin, and baicalin by human fecal microflora and its relation to cytotoxicity against tumor cells. PubMed: Dietary flavonoid sources in Australian adults. PubMed: In vivo pharmacokinetics of hesperidin are affected by treatment with glucosidase-like BglA protein isolated from yeasts. PubMed: Development of a potential reference material for evaluating antioxidant activity. PubMed: Dietary flavonoids differentially reduce oxidized LDL-induced apoptosis in human endothelial cells: role of MAPK- and JAK/STAT-signaling. PubMed: Peroxynitrite induced formation of the neurotoxins 5-S-cysteinyl-dopamine and DHBT-1: implications for Parkinson's disease and protection by polyphenols. PubMed: Dietary flavonoid intake and lung cancer--a population-based case-control study. PubMed: Analysis of food allergen structures and development of foods for allergic patients. PubMed: Distinct effects of naringenin and hesperetin on nitric oxide production from endothelial cells. PubMed: Transepithelial transport of flavanone in intestinal Caco-2 cell monolayers. PubMed: Neuroprotective effects of the citrus flavanones against H2O2-induced cytotoxicity in PC12 cells. PubMed: [Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60]. PubMed: Antimicrobial activity of flavonoids extracted from bergamot (Citrus bergamia Risso) peel, a byproduct of the essential oil industry. PubMed: Transepithelial transport of hesperetin and hesperidin in intestinal Caco-2 cell monolayers. PubMed: Activation of pro-survival Akt and ERK1/2 signalling pathways underlie the anti-apoptotic effects of flavanones in cortical neurons. PubMed: Enzymatic acylation of flavonoids: effect of the nature of the substrate, origin of lipase, and operating conditions on conversion yield and regioselectivity. PubMed: Inhibition of the formation of the neurotoxin 5-S-cysteinyl-dopamine by polyphenols. PubMed: Urine flavonoids and plasma carotenoids in the validation of fruit, vegetable and tea intake during pregnancy in the Norwegian Mother and Child Cohort Study (MoBa). PubMed: Urinary excretion of 13 dietary flavonoids and phenolic acids in free-living healthy subjects - variability and possible use as biomarkers of polyphenol intake. PubMed: Flavanone plasma pharmacokinetics from blood orange juice in human subjects. PubMed: Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells. PubMed: Attenuation of monocyte adhesion and oxidised LDL uptake in luteolin-treated human endothelial cells exposed to oxidised LDL. PubMed: Flavonoid content of U.S. fruits, vegetables, and nuts. PubMed: Age-related variations in flavonoid intake and sources in the Australian population. PubMed: The reaction of flavonoid metabolites with peroxynitrite. PubMed: Urinary flavonoids and phenolic acids as biomarkers of intake for polyphenol-rich foods. PubMed: Modulation of peroxynitrite-induced fibroblast injury by hesperetin: a role for intracellular scavenging and modulation of ERK signalling. PubMed: Activity and mRNA levels of enzymes involved in hepatic fatty acid oxidation in mice fed citrus flavonoids. PubMed: Evaluation of the anti-allergic activity of Citrus unshiu using rat basophilic leukemia RBL-2H3 cells as well as basophils of patients with seasonal allergic rhinitis to pollen. PubMed: Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction. PubMed: Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5). PubMed: Xanthine oxidase activity in vitro: effects of food extracts and components. PubMed: Impact of high pressure and pulsed electric fields on bioactive compounds and antioxidant activity of orange juice in comparison with traditional thermal processing. PubMed: Modulation of drug transport by selected flavonoids: Involvement of P-gp and OCT? PubMed: Interactive effects of polyphenols, tocopherol and ascorbic acid on the Cu2+-mediated oxidative modification of human low density lipoproteins. PubMed: Protection by food-derived antioxidants from UV-A1-induced photodamage, measured using living skin equivalents. PubMed: Degradation of neohesperidin dihydrochalcone by human intestinal bacteria. PubMed: Passive cutaneous anaphylaxis-inhibitory activity of flavanones from Citrus unshiu and Poncirus trifoliata. PubMed: The pig caecum model: a suitable tool to study the intestinal metabolism of flavonoids. PubMed: Identification and quantification of the conjugated metabolites derived from orally administered hesperidin in rat plasma. PubMed: Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport. PubMed: Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity. PubMed: Evaluation of hesperetin 7-O-lauryl ether as lipid-lowering agent in high-cholesterol-fed rats. PubMed: Changes in the levels of polymethoxyflavones and flavanones as part of the defense mechanism of Citrus sinensis (cv. Valencia Late) fruits against Phytophthora citrophthora. PubMed: Effect of the rootstock and interstock grafted in lemon tree (Citrus limon (L.) Burm.) on the flavonoid content of lemon juice. PubMed: Inhibitory activity of flavonoids from Prunus davidiana and other flavonoids on total ROS and hydroxyl radical generation. PubMed: Pro-oxidative properties of flavonoids in human lymphocytes. PubMed: Lipid-lowering efficacy of hesperetin metabolites in high-cholesterol fed rats. PubMed: Fasting plasma concentrations of selected flavonoids as markers of their ordinary dietary intake. PubMed: Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables. PubMed: Flavonoids in human urine as biomarkers for intake of fruits and vegetables. PubMed: In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids. PubMed: Purification and characterization of a beta-glucosidase from Citrus sinensis var. Valencia fruit tissue. PubMed: Identification and antioxidant activity of flavonoid metabolites in plasma and urine of eriocitrin-treated rats. PubMed: Inhibition of neoplastic transformation and bioavailability of dietary flavonoid agents. PubMed: In vitro biotransformation of flavonoids by rat liver microsomes. PubMed: Preparation and taste of certain glycosides of flavanones and of dihydrochalcones. PubMed: Antimutagenic effect of plant flavonoids in the Salmonella assay system. PubMed: Antihyperlipidemic effect of flavonoids from Prunus davidiana. PubMed: The influence of food flavonoids on the activity of some hepatic microsomal monooxygenases in rats. PubMed: Flavonoid sweeteners. Synthesis and intestinal absorption of selected sulfoalkylated hesperetin-3-14C derivatives in the rat. PubMed: Synthesis and metabolic fate of hesperetin-3-14C.