para-menthane-3,8-diol

2-(2-hydroxypropan-2-yl)-5-methylcyclohexan-1-ol

CAS: 42822-86-6 C10 H20 O2 MW: 172.26780000 herbal

Identification

Namepara-menthane-3,8-diol
IUPAC2-(2-hydroxypropan-2-yl)-5-methylcyclohexan-1-ol
CAS Number42822-86-6
EINECS255-953-7
FDA UNII6T6Z1Z1NC4
Molecular FormulaC10 H20 O2
Molecular Weight172.26780000
MDL NumberMFCD00191551
Nikkaji NumberJ309.978D
Beilstein2552262

Regulatory

JECFA Food Flavoring1416 p-menthane-3,8-diol
DG SANTE Food Flavourings02.246 p-menthane-3,8-diol
FEMA Number4053
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)42822-86-6 ; P-MENTHANE-3,8-DIOL

Physical Properties

Appearance white crystals (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 0.97600 to 0.98200 @ 25.00 °C.
Pounds per Gallon - (est). 8.121 to 8.171
Melting Point 34.00 to 35.00 °C. @ 760.00 mm Hg
Boiling Point 266.00 to 268.00 °C. @ 760.00 mm Hg
Vapor Pressure 0.001000 mmHg @ 25.00 °C. (est)
Flash Point 248.00 °F. TCC ( 120.00 °C. )
logP (o/w) 1.374 (est)
Soluble in alcohol
Insoluble in water

Cosmetic Information

CosIngcosmetic data
Cosmetic Useshair conditioning

Organoleptic Properties

Odor Description at 10.00 % in dipropylene glycol.

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for para-menthane-3,8-diol usage levels up to5.0000 % in the fragrance concentrate.
Maximised Survey-derived Daily Intakes (MSDI-EU)39.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)18.00 (μg/capita/day)
Structure ClassI
baked goods100.00000
beverages(nonalcoholic)48.00000
beverages(alcoholic)40.00000
breakfast cereal20.00000
cheese50.00000
chewing gum1500.00000
condiments / relishes50.00000
confectionery froastings200.00000
egg products-
fats / oils100.00000
fish products-
frozen dairy5.00000
fruit ices5.00000
gelatins / puddings150.00000
granulated sugar5.00000
gravies35.00000
hard candy500.00000
imitation dairy75.00000
instant coffee / tea25.00000
jams / jellies150.00000
meat products-
milk products75.00000
nut products15.00000
other grains-
poultry-
processed fruits20.00000
processed vegetables20.00000
reconstituted vegetables20.00000
seasonings / flavors15.00000
snack foods15.00000
soft candy500.00000
soups15.00000
sugar substitutes-
sweet sauces25.00000

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Exchange of knowledge

Need This Item for Flavor? You can contact the Chemical Sources Association.

Foreverest Resources Ltd.

Leading pine based chemicals supplier

Supplying turpentine based and natural/extracted flavor & fragrance ingredients.

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Potential Uses

hair conditioning FR herbal FR mint oral care agents skin conditioning

Natural Occurrence

litsea cubeba

Synonyms

citriodiol coolact 38D (Takasago) cubebaol cyclohexanemethanol, 2-hydroxy-a,a,4-trimethyl- cyclohexanol, 2-(2-hydroxy-2-propyl)-5-methyl- 2-(1- hydroxy-1-methyl ethyl)-5-methyl cyclohexanol 2-(1- hydroxy-1-methylethyl)-5-methylcyclohexanol 1- hydroxy-2-(1-methyl-1-hydroxyethyl)-5-methyl cyclohexane 2- hydroxy-a,a,4-trimethylcyclohexane methanol 2-(2- hydroxypropan-2-yl)-5-methylcyclohexan-1-ol 2-(2- hydroxypropan-2-yl)-5-methylcyclohexanol (1alpha,3beta,4beta)-p- menthan-3,8-diol (1alpha,3beta,4beta)-para- menthan-3,8-diol p- menthan-3,8-diol para- menthan-3,8-diol (1alpha,3beta,4beta)-p- menthane-3,8-diol (1alpha,3beta,4beta)-para- menthane-3,8-diol p- menthane-3,8-diol menthoglycol iso pulegol hydrate PubMed: Assessing the efficacy of candidate mosquito repellents against the background of an attractive source that mimics a human host. PubMed: A push-pull system to reduce house entry of malaria mosquitoes. PubMed: The efficacy of repellents against Aedes, Anopheles, Culex and Ixodes spp. - a literature review. PubMed: [Field efficacy of repellent formulation containing para-menthane-3,8-diol and lemongrass against Culicoides pachymerus (Diptera: Ceratopogonidae) in Colombia]. PubMed: Efficacy testing of several Ixodes ricinus tick repellents: different results with different assays. PubMed: Repellents and acaricides as personal protection measures in the prevention of tick-borne diseases. PubMed: Efficacy of DEET and non-DEET-based insect repellents against bites of Simulium damnosum vectors of onchocerciasis. PubMed: [Studies on anti-tumor metastatic constituents from Lindera glauca]. PubMed: Metabolism of (+)- and (-)-menthols by CYP2A6 in human liver microsomes. PubMed: Patent literature on mosquito repellent inventions which contain plant essential oils--a review. PubMed: [Personal protection measures against blood-sucking insects and ticks]. PubMed: Efficacy and safety of catnip (Nepeta cataria) as a novel filth fly repellent. PubMed: Dihydronepetalactones deter feeding activity by mosquitoes, stable flies, and deer ticks. PubMed: Percutaneous absorption of an insect repellent p-menthane-3,8-DIOL: a model for human dermal absorption. PubMed: Effective insect repellent formulation in both surfactantless and classical microemulsions with a long-lasting protection for human beings. PubMed: Acaricidal effects of Corymbia citriodora oil containing para-menthane-3,8-diol against nymphs of Ixodes ricinus (Acari: Ixodidae). PubMed: Repellency of MyggA Natural spray (para-menthane-3,8-diol) and RB86 (neem oil) against the tick Ixodes ricinus (Acari: Ixodidae) in the field in east-central Sweden. PubMed: PMD, a registered botanical mosquito repellent with deet-like efficacy. PubMed: Repellency of oils of lemon eucalyptus, geranium, and lavender and the mosquito repellent MyggA natural to Ixodes ricinus (Acari: Ixodidae) in the laboratory and field. PubMed: Efficacy of repellent products against caged and free flying Anopheles stephensi mosquitoes. PubMed: [Extraction and determination of volatile constituents in leaves of Eucalyptus citriodora]. PubMed: Laboratory and field tests of the effectiveness of the lemon-eucalyptus extract, Citridiol, as a repellent against land leeches of the genus Haemadipsa (Haemadipsidae). PubMed: Laboratory evaluation of mosquito repellents against Aedes albopictus, Culex nigripalpus, and Ochierotatus triseriatus (Diptera: Culicidae). PubMed: Enhancement effect of p-menthane-3,8-diol on in vitro permeation of antipyrine and indomethacin through Yucatan micropig skin. PubMed: Repellency of IR3535, KBR3023, para-menthane-3,8-diol, and deet to black salt marsh mosquitoes (Diptera: Culicidae) in the Everglades National Park. PubMed: Repellent activities of stereoisomers of p-menthane-3,8-diols against Anopheles gambiae (Diptera: Culicidae). PubMed: Efficacy of three insect repellents against the malaria vector Anopheles arabiensis. PubMed: Evaluation of a eucalyptus-based repellent against Anopheles spp. in Tanzania. PubMed: Studies on the metabolism of l-menthol in rats.