Identification

Namemethyl heptine carbonate
IUPACmethyl oct-2-ynoate
CAS Number111-12-6
EINECS203-836-6
FDA UNII0TTP6YT2T3
Molecular FormulaC9 H14 O2
Molecular Weight154.20898000
MDL NumberMFCD00009530
Nikkaji NumberJ22.135J
Beilstein1756887
CoE Number481

Regulatory

JECFA Food Flavoring1357 methyl 2-octynoate
DG SANTE Food Flavourings09.158 methyl 2-octynoate
FEMA Number2729
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)111-12-6 ; METHYL 2-OCTYNOATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 99.00 to 100.00
Halogens Chlorine free
Food Chemicals Codex Listed Yes
Specific Gravity 0.91900 to 0.92400 @ 25.00 °C.
Pounds per Gallon - (est). 7.647 to 7.689
Refractive Index 1.44600 to 1.44900 @ 20.00 °C.
Boiling Point 217.00 to 220.00 °C. @ 760.00 mm Hg, 75.00 °C. @ 4.00 mm Hg
Acid Value 1.00 max. KOH/g
Saponification Value 96.00 to 104.00
Vapor Pressure 0.125000 mmHg @ 25.00 °C. (est)
Flash Point 192.00 °F. TCC ( 88.89 °C. )
logP (o/w) 3.220 (est)
Shelf Life 12.00 month(s) or longer if stored properly.
Storage store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in alcohol
Insoluble in water
Stability non-discoloring in most media
Similar Items note

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesperfuming agents

Organoleptic Properties

Odor Strength high ,
Substantivity 240 hour(s) at 100.00 %
Odor Description
at 1.00 % in dipropylene glycol.
Green, vegetative, fruity, fatty, waxy, cucumber, melon and violet leaf-like with floral nuances
green, violet, vegetable, hay-like
Powerful, Green, Leaf like, Floral
Odor sample from Givaudan Corporation
Taste Description
at 15.00 ppm.
Strong, sweet melon character

Safety Information

Preferred SDSView
European informationMost important hazard(s):
Human Experience1 % solution: no irritation or sensitization.
Oral/Parenteral Toxicityoral-rat LD50 1530 mg/kg
Dermal Toxicityskin-rabbit LD50 3300 mg/kg
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
IFRA Critical EffectDermal sensitization
fragrance material specificationShould not be used such that the level in finished cosmetic products exceeds 0.002%. When used alone level in the finished cosmetic products should not exceed 0.01%. When present in combination, the combined level in the finished product should not exceed 0.01% of which methyl heptine carbonate should not be more than 0.002%
IFRA RESTRICTION LIMITS IN THE FINISHED PRODUCT (%)Category 1: Products applied to the lips
NotesIFRA FLAVOR REQUIREMENTS:
Maximised Survey-derived Daily Intakes (MSDI-EU)18.00 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA)38.00 (μg/capita/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods-
beverages(nonalcoholic)-
beverages(alcoholic)-
breakfast cereal-
cheese-
chewing gum13.00000
condiments / relishes-
confectionery froastings-
egg products-
fats / oils-
fish products-
frozen dairy-
fruit ices-
gelatins / puddings1.70000
granulated sugar-
gravies-
hard candy-
imitation dairy-
instant coffee / tea-
jams / jellies-
meat products-
milk products-
nut products-
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy-
soups-
sugar substitutes-
sweet sauces-

ACS International GmbH

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O'Laughlin Industries Inc.

Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics

Leading the Flavor and Fragrance Industry since 1980.

View All Website (973) 376-4600 olcorphk@hkstar.com

Penta International Corporation

Chemistry innovation

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Sigma-Aldrich

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SRS Aromatics Ltd

For over 25 years

Bringing flavour and fragrance into your world.

View All Website +44 (0) 1284 704076 info@srsaromatics.co.uk

Synerzine, Inc.

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TCI AMERICA

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The John D. Walsh Company, Inc

Suppliers Since 1942

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The Lermond Company

Your Sourcing Resource

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R C Treatt and Co Ltd

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Ernesto Ventós S.A.

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Vigon International

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Zanos Ltd.

Distributor of Speciality Chemicals and Natural Ingredients

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View All Website +44 (0) 1565 755899 sales@zanos.co.uk

Potential Uses

FR acacia FR apricot FR banana FR cucumber FR earth FR frangipani plumeria FR freesia FR green FR hay new mown hay FR honeysuckle FR jasmin FR jonquil leaf FR melon FR melon FR mimosa FR orris FR peach FR pear FR floral FR reseda FR rose scandal FR stephanotis straw FR strawberry FR sweet pea FL tea FR tuberose FR violet leaf FR wallflower FR woody

Natural Occurrence

not found in nature

Synonyms

folione (Givaudan) folione FCC (Givaudan) methyl 2-octinate methyl 2-octynate methyl 2-octynoate methyl hept-1-yne-1-carboxylate methyl heptin carbonate methyl heptine carbonate methyl heptyl carbonate methyl heptyne carbonate methyl oct-2-ynoate methyl pentyl acetylene carboxylate methyl pentylacetylenecarboxylate methyl-N-hept-1-yne-1-carboxylate oct-2-ynoic acid methyl ester 2- octynoic acid methyl ester 2- octynoic acid, methyl ester PubMed: Determination of suspected allergens in cosmetic products by headspace-programmed temperature vaporization-fast gas chromatography-quadrupole mass spectrometry. PubMed: Active sensitization and contact allergy to methyl 2-octynoate. PubMed: Is there evidence that methyl heptine carbonate causes allergic contact dermatitis? PubMed: Synthesis of seven-membered lactones via nickel- and zinc-catalyzed highly regio- and stereoselective cyclization of 2-iodobenzyl alcohols with propiolates. PubMed: Allergic contact dermatitis from methyl heptine and methyl octine carbonates. PubMed: [Cutaneous delayed hypersensitivity to methyl hepatine carbonate in pulmonary tuberculosis]. PubMed: [Methyl heptine carbonate skin test in lung cancer--correlation with stage and prognosis]. PubMed: [Newly recognized primary sensitizers, methyl heptine carbonate and costus root oil to evaluate cutaneous delayed hypersensitivity on various chest diseases (author's transl)].