Identification

Nameagarospirol
CAS Number23811-08-7
FDA UNIISearch
Molecular FormulaC15 H26 O
Molecular Weight222.37142000

Regulatory

Physical Properties

Assay 90.00 to 100.00
Food Chemicals Codex Listed No
Melting Point 56.00 to 58.00 °C. @ 760.00 mm Hg
Boiling Point 311.00 to 312.00 °C. @ 760.00 mm Hg (est)
Flash Point 238.00 °F. TCC ( 114.60 °C. ) (est)
logP (o/w) 4.703 (est)
Soluble in alcohol
Insoluble in water

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryfragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Recommendation for agarospirol usage levels up to1.0000 % in the fragrance concentrate.
Recommendation for agarospirol flavor usage levels up tonot for flavor use.

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Potential Uses

fixer FR spice FR woody

Natural Occurrence

agarwood oil @ 0.03% Data PMC agarwood oil @ 4.80% Data PMC atractylis oil atractylodes lancea fungus infected agarwood aquillaria agalocha PMC phoebe oil brazil @ 3.25% Data tansy oil (tanacetum annum l.) marocco @ 0.70% Data zingiber officinale root oil china @ 3.00% Data

Synonyms

2-[(2R,10S)-6,10- dimethyl spiro[4.5]dec-6-en-2-yl]-2-propanol 2-[(2R,10S)-6,10- dimethylspiro[4.5]dec-6-en-2-yl]-2-propanol 2-[(2R,6S)-6,10- dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol hinesol epi- hinesol spiro(4.5)dec-6-ene-2-methanol, a,a,6,10-tetramethyl-, (2R-(2a,5a(S*)))- (2R-(2alpha,5alpha(S*)))- alpha,alpha,6,10- tetramethyl spiro(4.5)dec-6-ene-2-methanol PubMed: [Studies on terpenoids from Zygophyllum fabago]. PubMed: Sulphur-containing compounds in the essential oil of Ferula alliacea roots and their mass spectral fragmentation patterns. PubMed: [Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea]. PubMed: Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells. PubMed: Traditional herbal medicine for the control of tropical diseases. PubMed: [Study on the chemical components of volatile oil from Euphorbia pekinensis radix]. PubMed: Molecular docking and ADME studies of natural compounds of Agarwood oil for topical anti-inflammatory activity. PubMed: Composition and evaluation of the anti-inflammatory and anticancer activities of the essential oil from Annona sylvatica A. St.-Hil. PubMed: Chemical composition and in vitro antimicrobial activity of the essential oil of Cyclotrichium leucotrichum from Iran. PubMed: In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei. PubMed: Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis. PubMed: Chemical composition of volatile oils of Aquilaria malaccensis (Thymelaeaceae) from Malaysia. PubMed: [Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis]. PubMed: [Advances in chemistry, molecular biology and pharmacological of Cangzhu]. PubMed: Identification of volatile compounds of Atractylode lancea rhizoma using supercritical fluid extraction and GC-MS. PubMed: [Fingerprint of volatile oil of Atractylodes lancea by GC-MS]. PubMed: [GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood]. PubMed: [Studies on chemical constituents in essential oil from wild Atractylodes lancea in dabie mountains]. PubMed: A phosphine-catalyzed [3+2] cycloaddition strategy leading to the first total synthesis of (-)-hinesol. PubMed: [The naphtha composing characteristics of geoherbs of Atractylodes lancea]. PubMed: [GC-MS analysis of essential oils from rhizomes of Atractylodes lancea (Thunb.) DC. and A. chinensis (DC.) Koidz]. PubMed: Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying. PubMed: Effects of sesquiterpenoids from "Oriental incenses" on acetic acid-induced writhing and D2 and 5-HT2A receptors in rat brain. PubMed: Inhibition of H+,K+ -ATPase by hinesol, a major component of So-jutsu, by interaction with enzyme in the E1 state. PubMed: Biotransformation of hinesol isolated from the crude drug Atractylodes lancea by Aspergillus niger and Aspergillus cellulosae. PubMed: Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures. PubMed: Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants. PubMed: A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis. PubMed: [Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes]. PubMed: Effect of jinkoh-eremol and agarospirol from agarwood on the central nervous system in mice. PubMed: Botanical and chemical evaluation of Atractylodes lancea plants propagated in vitro and by division of the rhizome. PubMed: Intestinal motility enhancing effect of Atractylodes lancea rhizome. PubMed: Antihepatotoxic principles of Atractylodes rhizomes. PubMed: Stereochemical relationships in spirovetivane sesquiterpenes: the total synthesis of hinesol. PubMed: Studies on the constituents of atractylodes. X. Correlation of hinesol and beta-vetivone.