agarospirol
hinesol
Identification
| Name | agarospirol |
| CAS Number | 23811-08-7 |
| FDA UNII | Search |
| Molecular Formula | C15 H26 O |
| Molecular Weight | 222.37142000 |
Regulatory
Physical Properties
| Assay | 90.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Melting Point | 56.00 to 58.00 °C. @ 760.00 mm Hg |
| Boiling Point | 311.00 to 312.00 °C. @ 760.00 mm Hg (est) |
| Flash Point | 238.00 °F. TCC ( 114.60 °C. ) (est) |
| logP (o/w) | 4.703 (est) |
| Soluble in | alcohol |
| Insoluble in | water |
Organoleptic Properties
| Odor Description | at 100.00 %. |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | fragrance agents |
| RIFM Fragrance Material Safety Assessment | Search |
| Recommendation for agarospirol usage levels up to | 1.0000 % in the fragrance concentrate. |
| Recommendation for agarospirol flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
2-[(2R,10S)-6,10-
dimethyl spiro[4.5]dec-6-en-2-yl]-2-propanol
2-[(2R,10S)-6,10-
dimethylspiro[4.5]dec-6-en-2-yl]-2-propanol
2-[(2R,6S)-6,10-
dimethylspiro[4.5]dec-9-en-2-yl]propan-2-ol
hinesol
epi-
hinesol
spiro(4.5)dec-6-ene-2-methanol, a,a,6,10-tetramethyl-, (2R-(2a,5a(S*)))-
(2R-(2alpha,5alpha(S*)))- alpha,alpha,6,10-
tetramethyl spiro(4.5)dec-6-ene-2-methanol
PubMed:
[Studies on terpenoids from Zygophyllum fabago].
PubMed:
Sulphur-containing compounds in the essential oil of Ferula alliacea roots and their mass spectral fragmentation patterns.
PubMed:
[Effects of Lime on Seedling Growth,Yield and Volatile Constituents of Atractylodes lancea].
PubMed:
Hinesol, a compound isolated from the essential oils of Atractylodes lancea rhizome, inhibits cell growth and induces apoptosis in human leukemia HL-60 cells.
PubMed:
Traditional herbal medicine for the control of tropical diseases.
PubMed:
[Study on the chemical components of volatile oil from Euphorbia pekinensis radix].
PubMed:
Molecular docking and ADME studies of natural compounds of Agarwood oil for topical anti-inflammatory activity.
PubMed:
Composition and evaluation of the anti-inflammatory and anticancer activities of the essential oil from Annona sylvatica A. St.-Hil.
PubMed:
Chemical composition and in vitro antimicrobial activity of the essential oil of Cyclotrichium leucotrichum from Iran.
PubMed:
In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei.
PubMed:
Insecticidal compounds from the essential oil of Chinese medicinal herb Atractylodes chinensis.
PubMed:
Chemical composition of volatile oils of Aquilaria malaccensis (Thymelaeaceae) from Malaysia.
PubMed:
[Simultaneous determination of atractylone, hinesol, beta-eudesmol, atrctylodin in Atractylodes lancea and hierarchical cluster analysis].
PubMed:
[Advances in chemistry, molecular biology and pharmacological of Cangzhu].
PubMed:
Identification of volatile compounds of Atractylode lancea rhizoma using supercritical fluid extraction and GC-MS.
PubMed:
[Fingerprint of volatile oil of Atractylodes lancea by GC-MS].
PubMed:
[GC-MS analysis of volatile constituents from five different kinds of Chinese eaglewood].
PubMed:
[Studies on chemical constituents in essential oil from wild Atractylodes lancea in dabie mountains].
PubMed:
A phosphine-catalyzed [3+2] cycloaddition strategy leading to the first total synthesis of (-)-hinesol.
PubMed:
[The naphtha composing characteristics of geoherbs of Atractylodes lancea].
PubMed:
[GC-MS analysis of essential oils from rhizomes of Atractylodes lancea (Thunb.) DC. and A. chinensis (DC.) Koidz].
PubMed:
Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying.
PubMed:
Effects of sesquiterpenoids from "Oriental incenses" on acetic acid-induced writhing and D2 and 5-HT2A receptors in rat brain.
PubMed:
Inhibition of H+,K+ -ATPase by hinesol, a major component of So-jutsu, by interaction with enzyme in the E1 state.
PubMed:
Biotransformation of hinesol isolated from the crude drug Atractylodes lancea by Aspergillus niger and Aspergillus cellulosae.
PubMed:
Atractylodes lancea autotetraploids induced by colchicine treatment of shoot cultures.
PubMed:
Random amplified polymorphic DNA analysis and variation of essential oil components of Atractylodes plants.
PubMed:
A comparative study on essential oil components of wild and cultivated Atractylodes lancea and A. chinensis.
PubMed:
[Study of components in crude drugs by headspace gas chromatography. II. Components of atractylodes].
PubMed:
Effect of jinkoh-eremol and agarospirol from agarwood on the central nervous system in mice.
PubMed:
Botanical and chemical evaluation of Atractylodes lancea plants propagated in vitro and by division of the rhizome.
PubMed:
Intestinal motility enhancing effect of Atractylodes lancea rhizome.
PubMed:
Antihepatotoxic principles of Atractylodes rhizomes.
PubMed:
Stereochemical relationships in spirovetivane sesquiterpenes: the total synthesis of hinesol.
PubMed:
Studies on the constituents of atractylodes. X. Correlation of hinesol and beta-vetivone.