guaiacyl propionate

2-methoxyphenyl propionate

CAS: 7598-60-9 C10 H12 O3 MW: 180.20324000 fruity

Identification

Nameguaiacyl propionate
CAS Number7598-60-9
FDA UNIIZ7SCO70Q61
Molecular FormulaC10 H12 O3
Molecular Weight180.20324000
Nikkaji NumberJ155.576F
XlogP31.90 (est)

Regulatory

JECFA Food Flavoring2017 guaiacol propionate
DG SANTE Food Flavourings09.943 guaiacol propionate
FEMA Number4609
FDANo longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF)7598-60-9 ; GUAIACOL PROPIONATE

Physical Properties

Appearance colorless to pale yellow clear liquid (est)
Assay 99.00 to 100.00
Food Chemicals Codex Listed No
Specific Gravity 1.09260 to 1.10260 @ 25.00 °C.
Pounds per Gallon - (est). 9.092 to 9.175
Refractive Index 1.52760 to 1.53760 @ 20.00 °C.
Boiling Point 227.00 to 229.00 °C. @ 760.00 mm Hg, 117.00 to 119.00 °C. @ 8.00 mm Hg
Vapor Pressure 0.076000 mmHg @ 25.00 °C. (est)
Flash Point 190.00 °F. TCC ( 87.78 °C. )
logP (o/w) 2.255 (est)
Soluble in water, 782.9 mg/L @ 25 °C (est)
Similar Items note

Organoleptic Properties

Odor Description fruity nutty vanilla

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categoryflavor and fragrance agents
RIFM Fragrance Material Safety AssessmentSearch
Maximised Survey-derived Daily Intakes (MSDI-EU)43.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI)74 (μg/person/day)
Threshold of Concern1800 (μg/person/day)
Structure ClassI
baked goods0.20000
beverages(nonalcoholic)0.10000
beverages(alcoholic)0.20000
breakfast cereal0.20000
cheese-
chewing gum-
condiments / relishes-
confectionery froastings0.20000
egg products-
fats / oils-
fish products-
frozen dairy0.10000
fruit ices0.10000
gelatins / puddings0.20000
granulated sugar-
gravies-
hard candy0.20000
imitation dairy0.20000
instant coffee / tea0.40000
jams / jellies-
meat products-
milk products-
nut products0.30000
other grains-
poultry-
processed fruits-
processed vegetables-
reconstituted vegetables-
seasonings / flavors-
snack foods-
soft candy0.20000
soups-
sugar substitutes0.10000
sweet sauces-
Dairy products, excluding products of category 02.0 (01.0)-
Fats and oils, and fat emulsions (type water-in-oil) (02.0)-
Edible ices, including sherbet and sorbet (03.0)0.10000
Processed fruit (04.1)-
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2)-
Confectionery (05.0)0.20000
Chewing gum (05.3)-
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0)0.20000
Bakery wares (07.0)0.20000
Meat and meat products, including poultry and game (08.0)-
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0)-
Eggs and egg products (10.0)-
Sweeteners, including honey (11.0)0.10000
Salts, spices, soups, sauces, salads, protein products, etc. (12.0)-
Foodstuffs intended for particular nutritional uses (13.0)-
Non-alcoholic ("soft") beverages, excl. dairy products (14.1)0.10000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2)0.20000
Ready-to-eat savouries (15.0)0.30000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0)0.20000

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Exchange of knowledge

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

guaiacol propionate 2- methoxyphenyl propanoate 2- methoxyphenyl propionate (2- methoxyphenyl) propanoate propionic acid o-methoxyphenyl propionate propionic acid ortho-methoxyphenyl propionate PubMed: In vitro degradation of lysine by ruminal fluid-based fermentations and by Fusobacterium necrophorum. PubMed: Quizalofop-p-ethyl-induced phytotoxicity and genotoxicity in Lemna minor and Lemna gibba. PubMed: Ancient wood of the Acqualadrone rostrum: materials history through gas chromatography/mass spectrometry and sulfur X-ray absorption spectroscopy. PubMed: Characterization of odor-active compounds of various cherry wines by gas chromatography-mass spectrometry, gas chromatography-olfactometry and their correlation with sensory attributes. PubMed: Precise design of artificial cofactors for enhancing peroxidase activity of myoglobin: myoglobin mutant H64D reconstituted with a "single-winged cofactor" is equivalent to native horseradish peroxidase in oxidation activity. PubMed: Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat. PubMed: Mathematical modeling of monolignol biosynthesis in Populus xylem. PubMed: Effects of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its ester derivatives on biofilm formation by two oral pathogens, Porphyromonas gingivalis and Streptococcus mutans. PubMed: Synthesis and anti-inflammatory activity of 3-(4'-geranyloxy-3'-methoxyphenyl)-2-trans propenoic acid and its ester derivatives. PubMed: Rational design of MOFs constructed from modified aromatic amino acids. PubMed: Effect of essential oil active compounds on rumen microbial fermentation and nutrient flow in in vitro systems. PubMed: Hybridization of modified-heme reconstitution and distal histidine mutation to functionalize sperm whale myoglobin. PubMed: The [(99m)Tc(N)(PNP)](2+) metal fragment: a technetium-nitrido synthon for use with biologically active molecules. The N-(2-methoxyphenyl)piperazyl-cysteine analogues as examples. PubMed: Identification of two electron-transfer sites in ascorbate peroxidase using chemical modification, enzyme kinetics, and crystallography. PubMed: Investigations of non-NMDA receptor-induced toxicity in serum-free antioxidant-rich primary cultures of murine cerebellar granule cells. PubMed: Haem propionates control oxidative and reductive activities of horseradish peroxidase by maintaining the correct orientation of the haem. PubMed: Antinociceptive and antiamnesic properties of the presynaptic cholinergic amplifier PG-9. PubMed: Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro. PubMed: Conjugated compounds in cow's milk. II. PubMed: Sore throat therapy. PubMed: CHROMATOGRAPHIC SEPARATION OF PHENOLS ON ION-EXCHANGE PAPER. PubMed: A REVIEW OF PHARMACOLOGIC AGENTS USED IN A PHYSICAL MEDICINE AND REHABILITATION SETTING. PubMed: NEWER DRUGS IN THE TREATMENT OF HEADACHE. PubMed: HYDROLYSIS OF AROMATIC ESTERS BY HUMAN DUODENAL CONTENTS.