pogostone

4H-pyran-4-one, 2-hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)-

CAS: 23800-56-8 C12 H16 O4 MW: 224.25632000

Identification

Namepogostone
IUPAC4-hydroxy-6-methyl-3-(4-methylpentanoyl)pyran-2-one
CAS Number23800-56-8
FDA UNIISearch
Molecular FormulaC12 H16 O4
Molecular Weight224.25632000
Nikkaji NumberJ19.811K

Regulatory

Physical Properties

Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Boiling Point 381.50 °C. @ 760.00 mm Hg (est)
Flash Point 294.00 °F. TCC ( 145.30 °C. ) (est)
logP (o/w) 0.750 (est)
Soluble in water, 2749 mg/L @ 25 °C (est)

No sensory data available

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynatural substances and extractives
Recommendation for pogostone usage levels up tonot for fragrance use.
Recommendation for pogostone flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

herba pogostemonis root patchouli patchouli oil china @ 3.83% Data

Synonyms

4- hydroxy-6-methyl-3-(4-methylpentanoyl)pyran-2-one 2- hydroxy-6-methyl-3-(4-methylpentanoyl)pyran-4-one 4H- pyran-4-one, 2-hydroxy-6-methyl-3-(4-methyl-1-oxopentyl)- PubMed: Protective effects of pogostone from Pogostemonis Herba against ethanol-induced gastric ulcer in rats. PubMed: In vitro and in vivo antibacterial activity of Pogostone. PubMed: Pogostone suppresses proinflammatory mediator production and protects against endotoxic shock in mice. PubMed: Identification of two chemotypes of Pogostemon cablin (Blanco) Benth. through DNA barcodes. PubMed: A gas chromatography-mass spectrometry method for the determination of pogostone in canine plasma and its application to a pharmacokinetic study. PubMed: Characterisation of the metabolism of pogostone in vitro and in vivo using liquid chromatography with mass spectrometry. PubMed: [Study on constituents of the aerial parts of Pogostemon cablin]. PubMed: Evaluation of the antibacterial activity of patchouli oil. PubMed: Preliminary antibacterial evaluation of the chemical compositions in Herba pogostemonis oil. PubMed: Insecticidal activity of pogostone against Spodoptera litura and Spodoptera exigua (Lepidoptera: Noctuidae). PubMed: LC-MS/MS determination of pogostone in rat plasma and its application in pharmacokinetic studies. PubMed: Analysis of Pogostemon cablin from pharmaceutical research to market performances. PubMed: Synthesis and antimicrobial evaluation of pogostone and its analogues. PubMed: Anti-Candida albicans activity and pharmacokinetics of pogostone isolated from Pogostemonis Herba. PubMed: Composition of the essential oil of Pogostemon travancoricus var. travancoricus. PubMed: Acaricidal activity of DHEMH, derived from patchouli oil, against house dust mite, Dermatophagoides farinae. PubMed: PREPARATIVE ISOLATION AND PURIFICATION OF FIVE FLAVONOIDS FROM POGOSTEMON CABLIN BENTH BY HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY AND PREPARATIVE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY. PubMed: [Identification method with significant specificity of volatile oil of Pogostemon cablin]. PubMed: GC-MS fingerprint of Pogostemon cablin in China. PubMed: [Re-study on characteristic fingerprint of volatile oil from Herba Pogostemonis by GC]. PubMed: [Investigation on the influential factors of the volatile oil and main constituent content in Pogostemon cablin]. PubMed: [Study on purification technology of patchouly oil with molecular distillation]. PubMed: [Two chemotypes of Pogostemon cablin and influence of region of cultivation and harvesting time on volatile oil composition]. PubMed: [Constituents analysis on volatile oil of Pogostemon cablin from different collection time cultivated in Hainan]. PubMed: [DNA profiling of Pogostemon cablin chemotypes differing in essential oil composition]. PubMed: [GC-MS analysis of volatile oil of herba Pogostemonis collected from Gaoyao county]. PubMed: [Chemical constituents of Pogostemon cablin (Blanco) Benth]. PubMed: Studies of the antibacterial activity of plant extracts and their constituents against periodontopathic bacteria.