aminopeptidase from lactococcus lactis
Identification
| Name | aminopeptidase from lactococcus lactis |
| CAS Number | 9031-94-1 |
| FDA UNII | Search |
| Molecular Formula | unspecified |
| MDL Number | MFCD00166325 |
Regulatory
| FDA Mainterm (SATF) | 977172-57-8 ; AMINOPEPTIDASE FROM LACTOCOCCUS LACTIS |
| FDA Regulation | FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE |
Physical Properties
| Food Chemicals Codex Listed | No |
| Storage | refrigerate in tightly sealed containers. |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| European information | Most important hazard(s): |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | enzyme preparations and microorganisms |
| Recommendation for aminopeptidase from lactococcus lactis usage levels up to | not for fragrance use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
aminopeptidase from lactococcus lactis
PubMed:
A Novel Glutamyl (Aspartyl)-Specific Aminopeptidase A from Lactobacillus delbrueckii with Promising Properties for Application.
PubMed:
Effect of varying the salt and fat content in Cheddar cheese on aspects of the performance of a commercial starter culture preparation during ripening.
PubMed:
Statistical optimization of cell disruption techniques for releasing intracellular X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis spp. lactis.
PubMed:
Oral administration of Lactococcus lactis-expressed recombinant porcine epidermal growth factor stimulates the development and promotes the health of small intestines in early-weaned piglets.
PubMed:
Recombinant porcine epidermal growth factor-secreting Lactococcus lactis promotes the growth performance of early-weaned piglets.
PubMed:
Production, active staining and gas chromatography assay analysis of recombinant aminopeptidase P from Lactococcus lactis ssp. lactis DSM 20481.
PubMed:
A new binding site involving the C-terminal domain to design specific inhibitors of PepX.
PubMed:
Metal preferences of zinc-binding motif on metalloproteases.
PubMed:
Characterization of certain bacterial strains for potential use as starter or probiotic cultures in dairy products.
PubMed:
Enzymatic activity of lactic acid bacteria (with antimicrobial properties) isolated from a traditional Spanish cheese.
PubMed:
To protect peptide pharmaceuticals against peptidases.
PubMed:
Regulatory phenotyping reveals important diversity within the species Lactococcus lactis.
PubMed:
Genotypic and technological characterization of Lactococcus lactis isolates involved in processing of artisanal Manchego cheese.
PubMed:
Rep-PCR characterization and biochemical selection of lactic acid bacteria isolated from the Delta area of Egypt.
PubMed:
Use of lantibiotic synthetases for the preparation of bioactive constrained peptides.
PubMed:
Diversity analysis of dairy and nondairy Lactococcus lactis isolates, using a novel multilocus sequence analysis scheme and (GTG)5-PCR fingerprinting.
PubMed:
Tolerance to high osmolality of the lactic acid bacterium Oenococcus oeni and identification of potential osmoprotectants.
PubMed:
Carbohydrate starvation causes a metabolically active but nonculturable state in Lactococcus lactis.
PubMed:
Genotypic and phenotypic diversity of Lactococcus lactis isolates from Batzos, a Greek PDO raw goat milk cheese.
PubMed:
Effect of high-pressure treatment and a bacteriocin-producing lactic culture on the proteolysis, texture, and taste of Hispánico cheese.
PubMed:
Construction and evaluation of food-grade vectors for Lactococcus lactis using aspartate aminotransferase and alpha-galactosidase as selectable markers.
PubMed:
Proteolysis of Hispanico cheese manufactured using lacticin 481-producing Lactococcus lactis ssp. lactis INIA 639.
PubMed:
The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity.
PubMed:
Characterization and kinetic analysis of enzyme-substrate recognition by three recombinant lactococcal tripeptidases.
PubMed:
Phylogenetic analysis of Lactococcus lactis subspecies based on decoding the sequence of the pepT tripeptidase gene, the pepV dipeptidase gene and 16S rRNA.
PubMed:
High-level gene expression in Lactobacillus plantarum using a pheromone-regulated bacteriocin promoter.
PubMed:
Catalytic activity of tripeptidase from Lactococcus lactis to which amino acid substitution was introduced according to natural mutation.
PubMed:
Use of bacteriocin promoters for gene expression in Lactobacillus plantarum C11.
PubMed:
Purification and characterization of the Streptococcus salivarius methionine aminopeptidase (MetAP).
PubMed:
Proteolysis, volatile compounds, and sensory evaluation in Hispánico cheese manufactured with the addition of a thermophilic adjunct culture, nisin, and calcium alginate-nisin microparticles.
PubMed:
Synthetic peptides as substrate for assaying the proteolytic activity of Lactobacillus helveticus.
PubMed:
High pressure effects on proteolytic and glycolytic enzymes involved in cheese manufacturing.
PubMed:
Identification and characterization of Lactobacillus helveticus PepO2, an endopeptidase with post-proline specificity.
PubMed:
Food-grade host/vector expression system for Lactobacillus casei based on complementation of plasmid-associated phospho-beta-galactosidase gene lacG.
PubMed:
Effect of wild strains of Lactococcus lactis on the volatile profile and the sensory characteristics of ewes' raw milk cheese.
PubMed:
Overexpression of peptidases in Lactococcus and evaluation of their release from leaky cells.
PubMed:
The structural basis for catalysis and specificity of the X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis.
PubMed:
Elevated enzyme release from lactococcal starter cultures on exposure to the lantibiotic lacticin 481, produced by Lactococcus lactis DPC5552.
PubMed:
A food-grade cloning vector for lactic acid bacteria based on the nisin immunity gene nisI.
PubMed:
Proteolysis in Hispánico cheese manufactured using a mesophilic starter, a thermophilic starter, and bacteriocin-producing Lactococcus lactis subsp. lactis INIA 415 adjunct culture.
PubMed:
Recombinant Lactococcus starters as a potential source of additional peptidolytic activity in cheese ripening.
PubMed:
An X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis: cloning, expression in Escherichia coli, and application for removal of N-terminal Pro-Pro from recombinant proteins.
PubMed:
Extracellular arginine aminopeptidase from Streptococcus gordonii FSS2.
PubMed:
Influence of adjunct cultures on ripening of reduced fat Edam cheeses.
PubMed:
Fluorescent method for monitoring cheese starter permeabilization and lysis.
PubMed:
Proteolysis and formation of volatile compounds in cheese manufactured with a bacteriocin-producing adjunct culture.
PubMed:
Expression of six peptidases from Lactobacillus helveticus in Lactococcus lactis.
PubMed:
Characterization by molecular cloning and sequencing of the gene encoding an aminopeptidase from Listeria monocytogenes.
PubMed:
The effects of cultivating lactic starter cultures with bacteriocin-producing lactic acid bacteria.
PubMed:
Leaky Lactococcus cultures that externalize enzymes and antigens independently of culture lysis and secretion and export pathways.
PubMed:
A food-grade cloning system for industrial strains of Lactococcus lactis.
PubMed:
Purification and molecular characterization of a tripeptidase (PepT) from Lactobacillus helveticus.
PubMed:
X-prolyl dipeptidyl aminopeptidase gene (pepX) is part of the glnRA operon in Lactobacillus rhamnosus.
PubMed:
Introduction of peptidase genes from Lactobacillus delbrueckii subsp. lactis into Lactococcus lactis and controlled expression.
PubMed:
PepS from Streptococcus thermophilus. A new member of the aminopeptidase T family of thermophilic bacteria.
PubMed:
Purification and characterization of a lysine-p-nitroanilide hydrolase, a broad specificity aminopeptidase, from the cytoplasm of Lactococcus lactis subsp. cremoris AM2.
PubMed:
Hydrolysis of alphas1- and beta-casein-derived peptides with a broad specificity aminopeptidase and proline specific aminopeptidases from Lactococcus lactis subsp. cremoris AM2.
PubMed:
The expression signals of the Lactobacillus brevis slpA gene direct efficient heterologous protein production in lactic acid bacteria.
PubMed:
Cloning, expression, and chromosomal stabilization of the Propionibacterium shermanii proline iminopeptidase gene (pip) for food-grade application in Lactococcus lactis.
PubMed:
Genetic characterization of pepP, which encodes an aminopeptidase P whose deficiency does not affect Lactococcus lactis growth in milk, unlike deficiency of the X-prolyl dipeptidyl aminopeptidase.
PubMed:
Catalytic properties of the cysteine aminopeptidase PepC, a bacterial bleomycin hydrolase.
PubMed:
Experimental evidence for the essential role of the C-terminal residue in the strict aminopeptidase activity of the thiol aminopeptidase PepC, a bacterial bleomycin hydrolase.
PubMed:
A chloride-inducible gene expression cassette and its use in induced lysis of Lactococcus lactis.
PubMed:
Purification and partial characterization of a tripeptidase from Pediococcus pentosaceus K9.2.
PubMed:
Food-grade controlled lysis of Lactococcus lactis for accelerated cheese ripening.
PubMed:
Proteolytic enzyme activity in lactococci grown in different pretreated milk media.
PubMed:
Purification and characterization of aminopeptidase P from Lactococcus lactis subsp. cremoris.
PubMed:
Autolysis of Lactococcus lactis caused by induced overproduction of its major autolysin, AcmA.
PubMed:
Presence of additional peptidases in Streptococcus thermophilus CNRZ 302 compared to Lactococcus lactis.
PubMed:
Structure-function relationships within the peptide deformylase family. Evidence for a conserved architecture of the active site involving three conserved motifs and a metal ion.
PubMed:
Characterization of a thiol-dependent endopeptidase from Lactobacillus helveticus CNRZ32.
PubMed:
A survey of polypeptide deformylase function throughout the eubacterial lineage.
PubMed:
The possible role of aminopeptidases from starter culture Lactococcus lactis subspecies cremoris AM2 in cheese making.
PubMed:
Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin.
PubMed:
The proteolytic system of Lactobacillus sanfrancisco CB1: purification and characterization of a proteinase, a dipeptidase, and an aminopeptidase.
PubMed:
Fate of peptides in peptidase mutants of Lactococcus lactis.
PubMed:
Detection and localization of peptidases in Lactococcus lactis with monoclonal antibodies.
PubMed:
A new, broad-substrate-specificity aminopeptidase from the dairy organism Lactobacillus helveticus SBT 2171.
PubMed:
Peptides inhibitory to endopeptidase and aminopeptidase from Lactococcus lactis ssp. lactis MG1363, released from bovine beta-casein by chymosin, trypsin or chymotrypsin.
PubMed:
Food-grade cloning and expression system for Lactococcus lactis.
PubMed:
DNA sequence analysis, expression, distribution, and physiological role of the Xaa-prolyldipeptidyl aminopeptidase gene from Lactobacillus helveticus CNRZ32.
PubMed:
Regulation of Proteolytic Enzyme Activity in Lactococcus lactis.
PubMed:
A study of the substrate specificity of aminopeptidase N from Lactococcus lactis subsp. cremoris Wg2.
PubMed:
An X-prolyl dipeptidyl aminopeptidase (pepX) gene from Lactobacillus helveticus.
PubMed:
Immunological and electrophoretic study of the proteolytic enzymes from various Lactococcus and Lactobacillus strains.
PubMed:
Comparison of proteolytic activities in various lactobacilli.
PubMed:
A non-essential glutamyl aminopeptidase is required for optimal growth of Lactococcus lactis MG1363 in milk.
PubMed:
Sequence analysis, distribution and expression of an aminopeptidase N-encoding gene from Lactobacillus helveticus CNRZ32 [gene 155 (1995) 89-93].
PubMed:
Purification, crystallization, and preliminary X-ray analysis of PepX, an X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis.
PubMed:
Nucleotide sequence of the lantibiotic Pep5 biosynthetic gene cluster and functional analysis of PepP and PepC. Evidence for a role of PepC in thioether formation.
PubMed:
Sequence analysis, distribution and expression of an aminopeptidase N-encoding gene from Lactobacillus helveticus CNRZ32.
PubMed:
Isolation of Lactococcus lactis nonsense suppressors and construction of a food-grade cloning vector.
PubMed:
An aminopeptidase P from Lactococcus lactis with original specificity.
PubMed:
Preparation of bacterial X-prolyl dipeptidyl aminopeptidase and its stabilization by organic cosolvents.
PubMed:
Cloning and nucleotide sequence analysis of the Lactobacillus delbrueckii ssp. lactis DSM7290 cysteine aminopeptidase gene pepC.
PubMed:
Effect of genetically modifying the lactococcal proteolytic system on ripening and flavor development in cheddar cheese.
PubMed:
Purification and characterization of a general aminopeptidase (St-PepN) from Streptococcus salivarius ssp. thermophilus CNRZ 302.
PubMed:
Characterization and expression of the Lactobacillus helveticus pepC gene encoding a general aminopeptidase.
PubMed:
Aminopeptidase N from Streptococcus salivarius subsp. thermophilus NCDO 573: purification and properties.
PubMed:
Gene cloning and characterization of PepC, a cysteine aminopeptidase from Streptococcus thermophilus, with sequence similarity to the eucaryotic bleomycin hydrolase.
PubMed:
Xaa-Pro-dipeptidyl-aminopeptidase from Lactococcus lactis catalyses kinetically controlled synthesis of peptide bonds involving proline.
PubMed:
Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant.
PubMed:
Crystallization and preliminary X-ray analysis of PepC, a thiol aminopeptidase from Lactoccocus lactis homologous to bleomycin hydrolase.
PubMed:
Cloning, sequencing and characterization of the pepIP gene encoding a proline iminopeptidase from Lactobacillus delbrueckii subsp. bulgaricus CNRZ 397.
PubMed:
Characterization of the Lactobacillus helveticus CNRZ32 pepC gene.
PubMed:
Effect of X-Prolyl Dipeptidyl Aminopeptidase Deficiency on Lactococcus lactis.
PubMed:
Degradation and debittering of a tryptic digest from beta-casein by aminopeptidase N from Lactococcus lactis subsp. cremoris Wg2.
PubMed:
Monitoring tripeptidase activity using capillary electrophoresis. Comparison with the ninhydrin assay.
PubMed:
Cloning and sequencing of pepC, a cysteine aminopeptidase gene from Lactococcus lactis subsp. cremoris AM2.
PubMed:
Identification of the active site serine of the X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis.
PubMed:
Characterization of the Lactococcus lactis pepN gene encoding an aminopeptidase homologous to mammalian aminopeptidase N.
PubMed:
Catalytic properties of X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. cremoris nTR.
PubMed:
Sequence of a gene (lap) encoding a 95.3-kDa aminopeptidase from Lactococcus lactis ssp. cremoris Wg2.
PubMed:
Localization of peptidases in lactococci.
PubMed:
Purification and characterization of an endopeptidase from Lactococcus lactis subsp. cremoris Wg2.
PubMed:
Characterization and overexpression of the Lactococcus lactis pepN gene and localization of its product, aminopeptidase N.
PubMed:
Ultrasound treatment for harvesting an aminopeptidase from lactic Acid bacteria and quantitation of the enzyme by enzyme-linked immunosorbent assays.
PubMed:
Replacement recombination in Lactococcus lactis.
PubMed:
Aminopeptidase A from Lactococcus lactis.
PubMed:
Aminotripeptidase activity in Lactococcus lactis subsp cremoris AM2.
PubMed:
Cloning and DNA sequence analysis of an X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. lactis NCDO 763.
PubMed:
Molecular cloning and sequence analysis of the X-prolyl dipeptidyl aminopeptidase gene from Lactococcus lactis subsp. cremoris.
PubMed:
Purification and Characterization of an Aminopeptidase from Lactococcus lactis subsp. cremoris Wg2.
PubMed:
Enzyme activities of cell-free extracts from mutant strains of lactic streptococci subjected to sublethal heating or freeze-thawing.
PubMed:
Purification and Characterization of an Aminopeptidase from Lactococcus lactis subsp. cremoris AM2.
PubMed:
Comparative peptide specificity of cell wall, membrane and intracellular peptidases of group N streptococci.