calcium laevo-5-methyl tetrahydrofolate

calcium L-5-methyltetrahydrofolate

CAS: 151533-22-1 C20 H23 Ca N7 O6 MW: 497.52551000

Identification

Namecalcium laevo-5-methyl tetrahydrofolate
IUPACcalcium (2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
CAS Number151533-22-1
FDA UNIIA9R10K3F2F
Molecular FormulaC20 H23 Ca N7 O6
Molecular Weight497.52551000
MDL NumberMFCD15146358

Regulatory

JECFA Food AdditiveCalcium L-5-Methyltetrahydrofolate

Physical Properties

Appearance whit to pale yellow crystalline powder (est)
Assay 95.00 to 100.00
Food Chemicals Codex Listed No
Flash Point 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in alkaline solutions

Organoleptic Properties

Odor Description at 100.00 %.

Safety Information

Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorynutrient supplements
Recommendation for calcium laevo-5-methyl tetrahydrofolate usage levels up tonot for fragrance use.
Recommendation for calcium laevo-5-methyl tetrahydrofolate flavor usage levels up tonot for flavor use.

American International Chemical, Inc.

Consistent sources

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

N-{4-[[((6S)-2- amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl}-L-glutamic acid calcium salt N-{4-[[((6S)-2- amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl}-laevo-glutamic acid calcium salt calcium (2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate calcium L-5-methyl tetrahydrofolate calcium L-5-methyltetrahydrofolate calcium laevo-5-methyltetrahydrofolate calcium N-(4-((((6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamate metafolin laevo- methylfolate, calcium laevo-5- methyltetrahydrofolic acid calcium salt nutrifolin PubMed: [Metafolin--alternative for folate deficiency supplementation in pregnant women]. PubMed: Folate status and homocysteine levels during a 24-week oral administration of a folate-containing oral contraceptive: a randomized, double-blind, active-controlled, parallel-group, US-based multicenter study. PubMed: Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. PubMed: Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics. PubMed: Bioequivalence of two leucovorin calcium tablet formulations.