carboxymethyl cellulose cross-linked
cross-linked carboxymethyl cellulose
Identification
| Name | carboxymethyl cellulose cross-linked |
| CAS Number | 74811-65-7 |
| FDA UNII | M28OL1HH48 |
| Molecular Formula | C8 H16 Na O8 |
| Molecular Weight | 263.19888928 |
Regulatory
| JECFA Food Additive | Cross-Linked Sodium Carboxymethyl Cellulose |
| GSFA Codex | Carboxymethyl cellulose, cross-linked- (cross-linked-Cellulose gum) (468) |
Physical Properties
| Appearance | white to grayish white powder (est) |
| Assay | 95.00 to 100.00 |
| Food Chemicals Codex Listed | No |
| Insoluble in | acetone |
Organoleptic Properties
| Odor Description | at 100.00 %. |
Safety Information
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | tabletting agents |
| Recommendation for carboxymethyl cellulose cross-linked usage levels up to | not for fragrance use. |
| Recommendation for carboxymethyl cellulose cross-linked flavor usage levels up to | not for flavor use. |
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Potential Uses
Natural Occurrence
Synonyms
cross-linked carboxymethyl cellulose
crosscarmellose sodium
cross-linked
sodium carboxymethyl cellulose
PubMed:
Uniform cross-linked cellulase aggregates prepared in millifluidic reactors.
PubMed:
Carboxymethyl cellulose film as a substrate for microarray fabrication.
PubMed:
Sericin-carboxymethyl cellulose porous matrices as cellular wound dressing material.
PubMed:
Aluminium and radiation cross-linked carboxymethyl sago pulp beads for colon targeted delivery.
PubMed:
Mechanochemical activation of vincamine mediated by linear polymers: assessment of some "critical" steps.
PubMed:
The anti-adhesive effect of thermally cross-linked gelatin film and its influence on the intestinal anastomosis in canine models.
PubMed:
Al3+ ion cross-linked interpenetrating polymeric network microbeads from tailored natural polysaccharides.
PubMed:
Evaluation of submucosally injected polyethylene glycol-based hydrogel and bovine cross-linked collagen in the canine urethra using cystoscopy, magnetic resonance imaging and histopathology.
PubMed:
Polyvinyl alcohol hydrogel decreases formation of adhesions in a rat model of peritonitis.
PubMed:
Mechanochemically induced disordered structures of vincamine: the different mediation of two cross-linked polymers.
PubMed:
Postoperative adhesion prevention with a new barrier: an experimental study.
PubMed:
Swelling behaviour and controlled drug release from cross-linked κ-carrageenan/NaCMC hydrogel by diffusion mechanism.
PubMed:
Injectable, mixed natural-synthetic polymer hydrogels with modular properties.
PubMed:
Postoperative adhesion prevention using a statin-containing cellulose film in an experimental model.
PubMed:
Comparison of in vitro methods of measuring mucoadhesion: ellipsometry, tensile strength and rheological measurements.
PubMed:
Preparation and In Vitro Evaluation of a Stomach Specific Drug Delivery System based on Superporous Hydrogel Composite.
PubMed:
Preparation of cross-linked carboxymethyl jackfruit starch and evaluation as a tablet disintegrant.
PubMed:
Use of cross-linked carboxymethyl cellulose for soft-tissue augmentation: preliminary clinical studies.
PubMed:
Comparison of the rheological properties of viscosity and elasticity in two categories of soft tissue fillers: calcium hydroxylapatite and hyaluronic acid.
PubMed:
Smart swelling biopolymer microparticles by a microfluidic approach: synthesis, in situ encapsulation and controlled release.
PubMed:
Evaluation of synthesized cross linked polyvinyl alcohol as potential disintegrant.
PubMed:
Wound healing evaluation of sodium fucidate-loaded polyvinylalcohol/sodium carboxymethylcellulose-based wound dressing.
PubMed:
Effect of sodium carboxymethylcellulose and fucidic acid on the gel characterization of polyvinylalcohol-based wound dressing.
PubMed:
Ionotropically cross-linked pH-sensitive IPN hydrogel matrices as potential carriers for intestine-specific oral delivery of protein drugs.
PubMed:
Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug.
PubMed:
Temporary polysaccharide dermal fillers: a model for persistence based on physical properties.
PubMed:
Raman spectroscopy and WAXS method as a tool for analysing ion-exchange properties of alginate hydrogels.
PubMed:
Carcinogen adsorbent prepared from DNA complex by gamma-ray irradiation.
PubMed:
Development of magnetically separable immobilized lipase by using cellulose derivatives and their application in enantioselective esterification of ibuprofen.
PubMed:
Clinical evaluation of bioadhesive hydrogels for topical delivery of hexylaminolevulinate to Barrett's esophagus.
PubMed:
Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers.
PubMed:
Development of pulsatile multiparticulate drug delivery system coated with aqueous dispersion Aquacoat ECD.
PubMed:
Adhesion formation and reherniation differ between meshes used for abdominal wall reconstruction.
PubMed:
Novel carboxymethylcellulose-based microporous hydrogels suitable for drug delivery.
PubMed:
Development of biodegradable aluminium carboxymethylcellulose matrices for mosquito larvicides.
PubMed:
Floating pellets containing bacterial antagonist for control sheath blight of rice: formulations, viability and bacterial release studies.
PubMed:
Formation of defined microporous 3D structures starting from cross-linked hydrogels.
PubMed:
Mucoadhesive vaginal tablets as veterinary delivery system for the controlled release of an antimicrobial drug, acriflavine.
PubMed:
Evaluation of certain food additives. Fifty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives.
PubMed:
Chitosan and sodium alginate-based bioadhesive vaginal tablets.
PubMed:
In-vitro evaluation of bioadhesion in particulate systems and possible improvement using interactive mixtures.
PubMed:
Isothermal calorimetry study of calcium caseinate and whey protein isolate edible films cross-linked by heating and gamma-irradiation.
PubMed:
Fast- and slow-release tablets for oral administration of flavonoids: rutin and quercetin.
PubMed:
Interpretation of mucoadhesive properties of polymer gel preparations using a tensile strength method.
PubMed:
Efficacy of a hyaluronan derivative gel in postsurgical adhesion prevention in the presence of inadequate hemostasis.
PubMed:
Mechanical and barrier properties of cross-linked soy and whey protein based films.
PubMed:
Evaluation and preparation of controlled release lipid micropheres of sulphamethizole by a congealable disperse phase encapsulation method.
PubMed:
Purification, characterization and amino-acid sequence analysis of a thermostable, low molecular mass endo-beta-1,4-glucanase from blue mussel, Mytilus edulis.
PubMed:
Enhancement of ursodeoxycholic acid bioavailability by cross-linked sodium carboxymethyl cellulose.
PubMed:
Oil-in water-emulsion gels: determination and mathematical treatment of flow properties.
PubMed:
A rheological assessment of the nature of interactions between mucoadhesive polymers and a homogenised mucus gel.
PubMed:
A rheological examination of the mucoadhesive/mucus interaction: the effect of mucoadhesive type and concentration.
PubMed:
Optimization of sustained-release tablet formulations: a four-component mixture experiment.
PubMed:
Buffer uptake and mass loss characteristics of freeze-dried cellulosic and alginate devices.
PubMed:
Viscoelasticity of anionic polymers and their mucociliary transport on the frog palate.
PubMed:
Compatibility study between acetylcysteine and some commonly used tablet excipients.
PubMed:
Black substrate for spectrophotometric determination of cellulase activity in coloured solutions.
PubMed:
Mixed-wall microcapsules made of cross-linked proteins and polysaccharides: preparation and properties.
PubMed:
Purification and characterization of an outer membrane protein adhesin from Haemophilus parainfluenzae HP-28.
PubMed:
A swellable polymer as carbamazepine dissolution rate enhancer.
PubMed:
The immunogenicity of soluble haptenated polymers is determined by molecular mass and hapten valence.
PubMed:
Cross-linked sodium carboxymethylcellulose as a carrier for dissolution rate improvement of drugs.
PubMed:
Cross-linking study on localization of the binding site for elongation factor 1 alpha on rat liver ribosomes.
PubMed:
Cross-linking of elongation factor 2 to rat-liver ribosomal proteins by 2-iminothiolane.
PubMed:
The subunit structure and active site sequence of porcine spleen deoxyribonuclease.
PubMed:
Application of cross-linked carboxymethyl cellulose degradation by beta-glucosidase and vaginal microbes to toxic shock syndrome.
PubMed:
Cross-linking study on protein topography of rat liver 60 S ribosomal subunits with 2-iminothiolane.
PubMed:
Effect of compressional force on tablets containing cellulosic disintegrators I: Dimensionless disintegration values.
PubMed:
Spatial arrangement of proteins within the small subunit of rat liver ribosomes studied by cross-linking.
PubMed:
The amino acid sequence of toxin D isolated from the venom of Indian cobra (Naja naja).
PubMed:
Effect of disintegrant type upon the relationship between compressional pressure and dissolution efficiency.
PubMed:
Isolation and characterization of pepsin-treated type III collagen from calf skin.
PubMed:
Collagen molecules: distribution of alpha chains.