lactalbumin
colostrum
Identification
| Name | lactalbumin |
| CAS Number | 9013-90-5 |
| FDA UNII | Search |
| Molecular Formula | unspecified |
| MDL Number | MFCD00130492 |
Regulatory
| FDA/DG SANTE Petitions, Reviews, Notices | GRN 763 |
| FDA Mainterm (SATF) | 9013-90-5 ; LACTALBUMIN |
| FDA Regulation | FDA PART 131 -- MILK AND CREAM |
Physical Properties
| Food Chemicals Codex Listed | No |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | skin conditioning |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | special dietary and nutritional additives |
| Recommendation for lactalbumin usage levels up to | not for fragrance use. |
| Recommendation for lactalbumin flavor usage levels up to | not for flavor use. |
No supplier data available
Potential Uses
Natural Occurrence
Synonyms
colostrum
lactalbumin
PubMed:
Nanotubular structures developed from whey-based α-lactalbumin fractions for food applications.
J-Stage:
Comparison of the Efficacy of Alpha-Lactalbumin from Equine, Bovine, and Human Milk in the Growth of Intestinal IEC-6 Cells
PubMed:
[The effect of natural whey proteins on mechanisms of blood pressure regulation].
PubMed:
[The effect of natural whey proteins on mechanisms of blood pressure regulation].
PubMed:
Spermine Sepharose as a clustered-charge anion exchange adsorbent.
PubMed:
Effects of Lactobacillus gasseri OLL2809 and α-lactalbumin on university-student athletes: a randomized, double-blind, placebo-controlled clinical trial.
PubMed:
Inhibition of dipeptidyl peptidase (DPP)-IV and α-glucosidase activities by pepsin-treated whey proteins.
PubMed:
Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.
PubMed:
Molecular mechanisms of the cytotoxicity of human α-lactalbumin made lethal to tumor cells (HAMLET) and other protein-oleic acid complexes.
PubMed:
Rapid mass spectrometric determination of disulfide connectivity in peptides and proteins.
PubMed:
A molecular complex of bovine milk protein and oleic acid selectively kills cancer cells in vitro and inhibits tumour growth in an orthotopic rat bladder tumour model.
PubMed:
Comprehensive assessment of milk composition in transgenic cloned cattle.
PubMed:
Structural insights into the stability perturbations induced by N-terminal variation in human and goat α-lactalbumin.
PubMed:
Global and local indices for characterizing biomolecular flexibility and rigidity.
PubMed:
Characterizing natural colloidal/particulate-protein interactions using fluorescence-based techniques and principal component analysis.
PubMed:
The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents.
PubMed:
A synthetic garden of state of the art natural protein nanoarchitectures dispersed in nanofluids.
PubMed:
A novel method for preparation of HAMLET-like protein complexes.
PubMed:
Acceleration of protein aggregation by amphiphilic peptides: transformation of supramolecular structure of the aggregates.
PubMed:
Selection of possible marker peptides for the detection of major ruminant milk proteins in food by liquid chromatography-tandem mass spectrometry.
PubMed:
Fibrillation of alpha-lactalbumin: effect of crocin and safranal, two natural small molecules from Crocus sativus.
PubMed:
Improvement of the antimicrobial and antioxidant activities of camel and bovine whey proteins by limited proteolysis.
PubMed:
Different folding pathways taken by highly homologous proteins, goat alpha-lactalbumin and canine milk lysozyme.
PubMed:
A bovine whey protein extract stimulates human neutrophils to generate bioactive IL-1Ra through a NF-kappaB- and MAPK-dependent mechanism.
PubMed:
Molecular and biotechnological advances in milk proteins in relation to human health.
PubMed:
Interaction of antitumor alpha-lactalbumin-oleic acid complexes with artificial and natural membranes.
PubMed:
Novel functions of bovine milk-derived alpha-lactalbumin: anti-nociceptive and anti-inflammatory activity caused by inhibiting cyclooxygenase-2 and phospholipase A2.
PubMed:
Expression and characterization of bioactive recombinant human alpha-lactalbumin in the milk of transgenic cloned cows.
PubMed:
Large-scale modulation of thermodynamic protein folding barriers linked to electrostatics.
PubMed:
Update on optimized purification and characterization of natural milk allergens.
PubMed:
Effect of alpha-lactalbumin on aerosol-OT phase structures in oil/water mixtures.
PubMed:
Role of intermolecular forces in defining material properties of protein nanofibrils.
PubMed:
Construction and characterization of a Lipotes vexillifer genomic DNA BAC library.
PubMed:
A role for milk proteins and their peptides in cancer prevention.
PubMed:
Effects of soybean glyceollins and estradiol in postmenopausal female monkeys.
PubMed:
Effect of the pH of heating on the qualitative and quantitative compositions of the sera of reconstituted skim milks and on the mechanisms of formation of soluble aggregates.
PubMed:
Emerging therapeutic potential of whey proteins and peptides.
PubMed:
alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.
PubMed:
On the complexation of proteins and polyelectrolytes.
PubMed:
Continuous matrix assisted refolding of alpha-lactalbumin by ion exchange chromatography with recycling of aggregates combined with ultradiafiltration.
PubMed:
Detection of a single nucleotide polymorphism in the human alpha-lactalbumin gene: implications for human milk proteins.
PubMed:
Matrix assisted refolding of proteins by ion exchange chromatography.
PubMed:
Preparation of antioxidant enzymatic hydrolysates from alpha-lactalbumin and beta-lactoglobulin. Identification of active peptides by HPLC-MS/MS.
PubMed:
R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable.
PubMed:
Effect of pH and ionic strength on competitive protein adsorption to air/water interfaces in aqueous foams made with mixed milk proteins.
PubMed:
Conformation-dependent interaction of alpha-lactalbumin with model and biological membranes: a spin-label ESR study.
PubMed:
Structures and relative free energies of partially folded states of proteins.
PubMed:
Use of cell culture media for cultivation of the mite pathogenic fungi Neozygites tanajoae and Neozygites floridana.
PubMed:
Autoimmune enteropathy and colitis in an adult patient.
PubMed:
The antiviral activity of naturally occurring proteins and their peptide fragments after chemical modification.
PubMed:
Antimicrobial peptides from food proteins.
PubMed:
Structural analysis, identification, and design of calcium-binding sites in proteins.
PubMed:
Plasma Trp/LNAA ratio increases during chronic ingestion of an alpha-lactalbumin diet in rats.
PubMed:
Cathepsin S and an asparagine-specific endoprotease dominate the proteolytic processing of human myelin basic protein in vitro.
PubMed:
Induced lactation in prepubertal Holstein heifers.
PubMed:
Inhibitors of complement activity in human breast-milk: a proposed hypothesis of their physiological significance.
PubMed:
Selective degradation of unfolded proteins by the self-compartmentalizing HtrA protease, a periplasmic heat shock protein in Escherichia coli.
PubMed:
Structural and thermodynamic responses of mutations at a Ca2+ binding site engineered into human lysozyme.
PubMed:
The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase.
PubMed:
Effects of purified bovine whey factors on cellular immune functions in ruminants.
PubMed:
Production of correctly folded recombinant [13C, 15N]-enriched guinea pig [Val90]-alpha-lactalbumin.
PubMed:
Purification and characterization of protease Ci, a cytoplasmic metalloendoprotease in Escherichia coli.
PubMed:
Large-scale production of a soluble human beta-1,4-galactosyltransferase using a Saccharomyces cerevisiae expression system.
PubMed:
Purification and characterization of a poly-L-lysine-activated serine endoprotease from Lumbricus rubellus.
PubMed:
In-vitro co-culture of early stage caprine embryos with oviduct and uterine epithelial cells.
PubMed:
Collagenase secretion accompanying changes in cell shape occurs only in the presence of a biologically active cytokine.
PubMed:
Proliferative and secretory activity in human breast during natural and artificial menstrual cycles.
PubMed:
Cationic activation of galactosyltransferase from rat mammary Golgi membranes by polyamines and by basic peptides and proteins.
PubMed:
New protein kinase from plasma membrane of Ehrlich ascites tumor cells activated by natural polypeptides.
PubMed:
Energy/protein interrelation in experimental food restriction.
PubMed:
Nutritional evaluations of three dietary levels of lactalbumin throughout the lifespan of two generations of Syrian hamsters.
PubMed:
Changes in lactoferrin, immunoglobulin G, bovine serum albumin, and alpha-lactalbumin during acute experimental and natural coliform mastitis in cows.
PubMed:
Environmental degradation of the insect growth regulator methoprene. VIII. Boving metabolism to natural products in mild and blood.
PubMed:
A fluorimetric study of the interactions of insolubilized human alpha-lactalbumin with galactosyl transferase (A-protein) and with anti-alpha-lactalbumin antibodies.