sodium stearyl fumarate

sodium (E)-4-octadecoxy-4-oxobut-2-enoate

CAS: 4070-80-8 C22 H39 Na O4 MW: 390.53939928

Identification

Namesodium stearyl fumarate
IUPACsodium (E)-4-octadecoxy-4-oxobut-2-enoate
CAS Number4070-80-8
EINECS223-781-1
FDA UNII7CV7WJK4UI
Molecular FormulaC22 H39 Na O4
Molecular Weight390.53939928
MDL NumberMFCD00236640
Nikkaji NumberJ217.877J

Regulatory

FDA Mainterm (SATF)4070-80-8 ; SODIUM STEARYL FUMARATE
FDA RegulationFDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION

Physical Properties

Food Chemicals Codex Listed No
Boiling Point 483.40 °C. @ 760.00 mm Hg (est)
Vapor Pressure 0.000000 mmHg @ 25.00 °C. (est)
Flash Point 308.00 °F. TCC ( 153.50 °C. ) (est)
logP (o/w) 8.789 (est)
Soluble in water, 0.0001422 mg/L @ 25 °C (est)

Cosmetic Information

CosIngcosmetic data
Cosmetic Usesbulking agents

No sensory data available

Safety Information

Preferred SDSView
Oral/Parenteral ToxicityNot determined
Dermal ToxicityNot determined
Inhalation ToxicityNot determined

GHS Classification

['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']

Safety in Use

Categorydough conditioners, conditioning agents, stabilizing agents
Recommendation for sodium stearyl fumarate usage levels up tonot for fragrance use.
Recommendation for sodium stearyl fumarate flavor usage levels up tonot for flavor use.

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Potential Uses

None Found

Natural Occurrence

not found in nature

Synonyms

sodium (E)-4-octadecoxy-4-oxobut-2-enoate sodium monooctadecyl fumarate sodium monostearyl fumarate sodium octadecyl fumarate PubMed: Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders. PubMed: Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets. PubMed: [Theoretical modeling and experimental research on direct compaction characteristics of multi-component pharmaceutical powders based on the Kawakita equation]. PubMed: Influence of emulsifier structure on lipid bioaccessibility in oil-water nanoemulsions. PubMed: [Preparation and application on compound excipient of sodium stearyl fumarate and plasdone S-630]. PubMed: Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate. PubMed: Development of novel bepotastine salicylate salt bioequivalent to the commercial bepotastine besilate in beagle dogs. PubMed: Measurement of flowability of lubricated powders by the vibrating tube method. PubMed: [Selected adjuvants as carriers of a dry extract of common ivy (Hedera helix L.)]. PubMed: [A new water-soluble lubricant of tablets-L-leucine combined with PEG6000]. PubMed: Preparation and physicochemical evaluation of a new tacrolimus tablet formulation for sublingual administration. PubMed: Energy evaluation of the compaction process of directly compressible isomalt. PubMed: Formulation and In-Vitro Evaluation of Ocular Ciprofloxacin-Containing Minitablets Prepared with Different Combinations of Carbopol 974P and Various Cellulose Derivatives. PubMed: [Tableting technology of a dry extract from Solidago virgaurea L. with the use of silicified microcrystalline cellulose (Prosolv) and other selected auxiliary substances]. PubMed: Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia. PubMed: Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol. PubMed: A study of the properties of tablets from the mixtures of directly compressible starch and directly compressible lactitol. PubMed: A study of the properties of compacts from silicified microcrystalline celluloses. PubMed: Nanoscopic friction behavior of pharmaceutical materials. PubMed: Packed column supercritical fluid chromatography of sodium stearyl fumarate aqueous suspension. PubMed: Intrinsic adhesion force of lubricants to steel surface. PubMed: Potential application of silicified microcrystalline cellulose in direct-fill formulations for automatic capsule-filling machines. PubMed: Comparative evaluation of co-processed lactose and microcrystalline cellulose with their physical mixtures in the formulation of folic acid tablets. PubMed: [The effect of two lubricants (magnesium stearate and pruv) in the formation of tablets of four anti-ulcer agents/ by means of direct compression]. PubMed: Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution. PubMed: The absorption and metabolism of orally administered tritium labeled sodium stearyl fumarate in the rat and dog.