sodium stearyl fumarate
sodium (E)-4-octadecoxy-4-oxobut-2-enoate
Identification
| Name | sodium stearyl fumarate |
| IUPAC | sodium (E)-4-octadecoxy-4-oxobut-2-enoate |
| CAS Number | 4070-80-8 |
| EINECS | 223-781-1 |
| FDA UNII | 7CV7WJK4UI |
| Molecular Formula | C22 H39 Na O4 |
| Molecular Weight | 390.53939928 |
| MDL Number | MFCD00236640 |
| Nikkaji Number | J217.877J |
Regulatory
| FDA Mainterm (SATF) | 4070-80-8 ; SODIUM STEARYL FUMARATE |
| FDA Regulation | FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION |
Physical Properties
| Food Chemicals Codex Listed | No |
| Boiling Point | 483.40 °C. @ 760.00 mm Hg (est) |
| Vapor Pressure | 0.000000 mmHg @ 25.00 °C. (est) |
| Flash Point | 308.00 °F. TCC ( 153.50 °C. ) (est) |
| logP (o/w) | 8.789 (est) |
| Soluble in | water, 0.0001422 mg/L @ 25 °C (est) |
Cosmetic Information
| CosIng | cosmetic data |
| Cosmetic Uses | bulking agents |
No sensory data available
Safety Information
| Preferred SDS | View |
| Oral/Parenteral Toxicity | Not determined |
| Dermal Toxicity | Not determined |
| Inhalation Toxicity | Not determined |
GHS Classification
['GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)', 'GHS Label elements, including precautionary statements']
Safety in Use
| Category | dough conditioners, conditioning agents, stabilizing agents |
| Recommendation for sodium stearyl fumarate usage levels up to | not for fragrance use. |
| Recommendation for sodium stearyl fumarate flavor usage levels up to | not for flavor use. |
Potential Uses
Natural Occurrence
Synonyms
sodium (E)-4-octadecoxy-4-oxobut-2-enoate
sodium monooctadecyl fumarate
sodium monostearyl fumarate
sodium octadecyl fumarate
PubMed:
Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders.
PubMed:
Investigating critical effects of variegated lubricants, glidants and hydrophilic additives on lag time of press coated ethylcellulose tablets.
PubMed:
[Theoretical modeling and experimental research on direct compaction characteristics of multi-component pharmaceutical powders based on the Kawakita equation].
PubMed:
Influence of emulsifier structure on lipid bioaccessibility in oil-water nanoemulsions.
PubMed:
[Preparation and application on compound excipient of sodium stearyl fumarate and plasdone S-630].
PubMed:
Formulating weakly basic HCl salts: relative ability of common excipients to induce disproportionation and the unique deleterious effects of magnesium stearate.
PubMed:
Development of novel bepotastine salicylate salt bioequivalent to the commercial bepotastine besilate in beagle dogs.
PubMed:
Measurement of flowability of lubricated powders by the vibrating tube method.
PubMed:
[Selected adjuvants as carriers of a dry extract of common ivy (Hedera helix L.)].
PubMed:
[A new water-soluble lubricant of tablets-L-leucine combined with PEG6000].
PubMed:
Preparation and physicochemical evaluation of a new tacrolimus tablet formulation for sublingual administration.
PubMed:
Energy evaluation of the compaction process of directly compressible isomalt.
PubMed:
Formulation and In-Vitro Evaluation of Ocular Ciprofloxacin-Containing Minitablets Prepared with Different Combinations of Carbopol 974P and Various Cellulose Derivatives.
PubMed:
[Tableting technology of a dry extract from Solidago virgaurea L. with the use of silicified microcrystalline cellulose (Prosolv) and other selected auxiliary substances].
PubMed:
Design of pH-independent extended release matrix tablets of minocycline hydrochloride for the treatment of dementia.
PubMed:
Effect of the type of lubricant on the characteristics of orally disintegrating tablets manufactured using the phase transition of sugar alcohol.
PubMed:
A study of the properties of tablets from the mixtures of directly compressible starch and directly compressible lactitol.
PubMed:
A study of the properties of compacts from silicified microcrystalline celluloses.
PubMed:
Nanoscopic friction behavior of pharmaceutical materials.
PubMed:
Packed column supercritical fluid chromatography of sodium stearyl fumarate aqueous suspension.
PubMed:
Intrinsic adhesion force of lubricants to steel surface.
PubMed:
Potential application of silicified microcrystalline cellulose in direct-fill formulations for automatic capsule-filling machines.
PubMed:
Comparative evaluation of co-processed lactose and microcrystalline cellulose with their physical mixtures in the formulation of folic acid tablets.
PubMed:
[The effect of two lubricants (magnesium stearate and pruv) in the formation of tablets of four anti-ulcer agents/ by means of direct compression].
PubMed:
Drug-excipient interactions resulting from powder mixing. IV: Role of lubricants and their effect on in vitro dissolution.
PubMed:
The absorption and metabolism of orally administered tritium labeled sodium stearyl fumarate in the rat and dog.